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Genfine Purifier 32, Руководство пользователя

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Page  4  of 38 

Magnetic 

Bead 

Processing 

Principle 

 

Figure 2- 3 MPP 

Magnetic 

bead 

processing

 

Magnetic bead processing can be divided into four separate steps: 

⚫

 

Bind magnetic beads 

⚫

 

Release magnetic beads 

⚫

 

Rinse magnetic beads 

⚫

 

Concentration 

Bind 

magnetic 

beads

 

In  the  magnetic  bead  binding  process,  the  magnetic  rod  is 
completely  inside  the  magnetic  tip  comb.  The  magnetic  rod  and 
magnetic tip comb move slowly up and down in the microwell plate 
to collect the magnetic beads to  the top of the magnetic tip comb. 
After the magnetic rod and magnetic tip comb are bound with the 
magnetic  beads,  they  are  lifted  from  the  microwell  plate  and 
transferred to the next microwell plate.

 

Release 

magnetic 

beads

 

After  the  magnetic  beads  are  collected,  the  magnetic  rod  and 
magnetic tip comb are lifted from the microwell plate together and 
transferred to the next microwell plate containing the reagent. The 
magnetic  rod  and  magnetic  tip  comb  are  placed  together  and  the 
magnetic rod is lifted. 

The magnetic beads are released by moving the magnetic tip comb 

up  and  down  at  high  speed,  and  all  the  magnetic  beads  are  fully 

mixed with the substrate of the next reaction. 

 

Содержание Purifier 32

Страница 1: ...GENFINE Purifier 32 User Manual V1 3 GENFINE Biotech Changzhou Co Ltd...

Страница 2: ...ter 3 Installation and Packaging 6 Delivery Check 6 Unboxing 6 Integrity and Damage Check 6 Environment Requirement 7 Precautions and Restrictions 7 Installation Settings 8 Power Connection 10 Packagi...

Страница 3: ...terpretation of Graphics Symbols and Abbreviations 31 Manual revision date 32 2021 01 29 32 Target customers 32 More information 32 Safety and User Guide 32 Chapter 8 Manufacturer and Medical Device I...

Страница 4: ...is magnetic beads adsorption method Purifier 32 Figure 1 1 is designed for automatic transfer and processing of magnetic beads in standard microwell plates The patented technology of the Purifier 32...

Страница 5: ...an electrical part This section shows the front and back views of Purifier 32 Front View See Figure 2 1 for the front view of Purifier 32 Figure 2 1 Purifier 32 Front View 96 deep well plate loading p...

Страница 6: ...agents are loaded into microwell plate The magnetic tip comb is placed on the correct microwell plate and can be automatically loaded onto the moving platform According to the program the microwell pl...

Страница 7: ...top of the magnetic tip comb After the magnetic rod and magnetic tip comb are bound with the magnetic beads they are lifted from the microwell plate and transferred to the next microwell plate Releas...

Страница 8: ...c bead processing The solution volume of the former microwell plate can be larger than that of the next microwell plate to achieve the purpose of concentration see Figure 2 5 Figure 2 4 Concentration...

Страница 9: ...porting without package please handle carefully It is recommended that two people move the equipment together and take appropriate precautions to avoid injury When lifting the instrument place the fin...

Страница 10: ...smoke and dust Ambient temperatures range from 10 C to 40 C Humidity is low and condensation does not occur relative humidity is below 80 Care should be taken not to operate the instrument in an envi...

Страница 11: ...is product should not be used by people wearing pacemakers or metal prostheses Prosthetic devices such as pacemakers or prostheses may be affected or damaged by close contact with strong magnetic fiel...

Страница 12: ...vertical row holes of the 96 well plate Figure 3 3 Installation of 96 well plate Installation of magnetic tip comb The magnetic tip comb must be inserted into the bottom of the card slot of the magne...

Страница 13: ...manufacturer 1 Connect the power cord to the power connector and insert into the instrument Figure 2 2 2 Connect the power supply to a properly installed well grounded power outlet Packaging Settings...

Страница 14: ...kaging Put the instrument in a bag fix eight corners with foam and put into a carton Then put the carton into a big packaging box and seal the packaging box for direct transportation 3 5 Inside schema...

Страница 15: ...Warning Never operate the instrument on an ungrounded electrical outlet Control Panel This section describes the control panel and internal software of Purifier 32 Touch Screen The home page of the t...

Страница 16: ...an select any file in the table for example by clicking the DNA button Detailed file is as shown in the figure No step or parameter can be edited and deleted Run File Click Run to start file running C...

Страница 17: ...g Click Cancel to stop and exit file running Custom There is a custom function module on the home page Users can create and manage their own accounts create modify save and delete their own personal f...

Страница 18: ...keyboard to enter a name and password A password is not required When the account is signed up it will be displayed in the file list Log in After the account is signed up the user can directly log in...

Страница 19: ...screen Click Creat new program to resume The user can set the program name icon and brief description and then click Next Program Details This interface shows all details of the program such as step...

Страница 20: ...set and select relevant parameters in this interface The meaning of each button is as follows The current step is set to work in plate position 1 Set the function of the current step Return to previou...

Страница 21: ...is in the deep well plate Duration Duration The magnetic rod is separated from the magnetic tip comb Percentage of position of magnetic tip comb in the well plate For every 10 decrease the correspondi...

Страница 22: ...es temperature settings The user can set the heating temperature and duration Temperature range room temperature 99 C Click to complete program settings and return to the Program Details interface The...

Страница 23: ...nterface to set the parameters of Purifier 32 After enter the Settings interface the user can see the status of the UV light and HEPA filter which can remind the user to replace the UV light and HEPA...

Страница 24: ...the user interface and the motherboard and both versions must be the same Special magnetization option The user may use this function only with the confirmation of the manufacturer Shutting Down Turn...

Страница 25: ...netic tip comb as biohazard waste Emergencies If an abnormal situation occurs during operation such as liquid spilling into the instrument please follow the steps below 1 Turn off the instrument Figur...

Страница 26: ...th water or a mild detergent Although Purifier 32 is made of high quality materials you must remove the spilled salt solution chemical solvent acid or alkaline solution from the surface immediately to...

Страница 27: ...2 near magnetic tapes computer discs or other magnetic storage devices such as credit cards as they may be damaged by the strong magnetic field of the magnetic rod of Purifier 32 Do not put the magnet...

Страница 28: ...authorized trained personnel in a well ventilated room wearing disposable gloves protective glasses and clothing Follow regular laboratory procedures for decontamination The decontamination instructi...

Страница 29: ...f the package see Appendix A Certificate of Decontamination Packaging for repair If you need repair the instrument please package it following the guidelines below Caution Before removing the instrume...

Страница 30: ...problems Fill in the system log System logs including operation summary maintenance procedures error messages and other useful information about system are very useful for proper maintenance of the sy...

Страница 31: ...biological waste The disposal of the instrument is carried out in accordance with the laws and regulations of the local authorities on the recycle of electronic equipment and waste Disposal procedures...

Страница 32: ...C packed by transport package Storage condition 25 C to 50 C packed by transport package Rated voltage AC110 240V 50Hz 60Hz Rated power 350W Internal memory More than 500 programs File input USB stora...

Страница 33: ...o 99 C the device is at room temperature Accuracy of heating module 1 C maximum 75 C the device is at room temperature Display 5 LCD 480 800 pixel color display Safety parameters The safety parameters...

Страница 34: ...name Quantity Unit 1 Automatic nucleic acid extractor 1 pcs 2 Allen wrench 1 pcs 3 Power cable 1 pcs 4 Deep well plate 2 pcs 5 Magnetic tip comb 4 pcs 6 Warranty Card 1 pcs 7 Certificate of quality 1...

Страница 35: ...e will be very grateful Safety and User Guide To reduce the risk of injury or biohazard contamination and to avoid fire or electric shock always follow basic safety precautions when using Purifier 32...

Страница 36: ...o keep the instrument in its best condition and ensure maximum reliability Poorly maintained instruments may cause abnormal test results Warning The product has a strong permanent magnet This product...

Страница 37: ...ech Changzhou Co Ltd Production address Building E4 No 9 Changyang Road West Taihu Technology Industrial Park Changzhou City Jiangsu Province Contact information 0519 83761557 Production record certif...

Страница 38: ...sional Purifier 321002 Purifier 32 standard without NFC or heater Purifier 321003 Purifier 32 demo List of accessories and consumables Table 7 2 List of accessories and consumables used with Purifier...

Страница 39: ...FM103 M103 FineMag Plasma Circulating DNA Maxi Kit FM107 M107 FineMag Universal Genomic DNA Kit FM202 M202 FineMag Plant Genomic DNA Kit FM302 M302 FineMag Swab Genomic DNA Kit FM401 M401 FineMag Sal...

Страница 40: ..._________________________ ___________________________________________________________ Decontamination procedure1 ________________________________________________ ______________________________________...

Страница 41: ...Page 38 of 38 Appendix B System Log Device name and number User Date Note...

Страница 42: ...Page 39 of 42 GENFINE Biotech Changzhou Co Ltd www genfine com marketing genfine com...

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