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Müse Parameter Descriptions
285
PaO
2
Set-point
The PaO
2
Set-point parameter is a set-point for PaO
2
. When PaO
2
is below the set-point value,
progressive stimulation of spontaneous minute ventilation occurs. Both tidal volume and respiratory
rate rise, which under appropriate conditions results in PaO
2
moving closer to the set-point. Factors
that influence this control effort include baseline tidal volume, baseline respiratory rate, respiratory
gain, O
2
consumption, respiratory quotient, lung compliances, chest wall compliance, bronchial
resistances, the presence of artificial airways in the simulator and the inspired gas mixture. Minute
ventilation is not affected for PaO
2
above the set-point.
For example, if PaO
2
Set-point is set to 100 mmHg and PaO
2
drops to 90 mmHg, ventilatory
stimulation occurs. When the PaO
2
reaches the new set-point, the simulator’s respiratory rate and tidal
volume are again controlled to maintain PaCO
2
at the PaCO
2
set-point. Also, see PaCO
2
Set-point .
Default : 100.00 mmHg
Range : 20.0 mmHg - 100.0 mmHg
I to E Ratio (1:X)
The I to E Ratio (1:X) parameter sets the inspiratory-expiratory (I:E) ratio for spontaneous ventilation. At
the default setting, the time for exhalation is twice that of inhalation.
Default : 2
Range : 0.5 - 7.0
PetCO
2
- PaCO
2
Factor
The PetCO
2
- PaCO
2
Factor adjusts the end-tidal CO
2
relative to the PaCO
2
. At the default value of 1,
PetCO
2
very closely approximates PaCO
2
. When PetCO
2
- PaCO
2
Factor is set at a value of 2, PetCO
2
is
approximately one half of PaCO
2
. PetCO
2
depends on CO
2
production and alveolar ventilation. Because
the alveolar dead space is not modeled physically in the hardware, the responses to changes in
mechanical ventilation settings may not be exact. The use of the Onset feature (e.g., onset over a 1-
minute period) is recommended for this parameter.
Default : 1
Range : 0.9 - 10.0