13
EDUCATIONAL MATERIAL FOR RISK MINIMISATION
If You Stop or Lower Your Dose of Duodopa
®
It is important that you do not stop having Duodopa
®
or
lower your dose until told to do so by your doctor� Suddenly
stopping or lowering your Duodopa
®
dose may result in a
serious problem called
Neuroleptic Malignant Syndrome
�
The signs may include:
• Fast heart beat, changing blood pressure and sweating
followed by fever
• Faster breathing, muscle stiffness, lower consciousness
and coma
• Higher levels of a protein in your blood (an enzyme called
creatine phosphokinase)� This is measured by your doctor�
This problem is more likely to happen if you are also taking
a medicine called an
antipsychotic
�
If you have any further questions on the use of this product,
ask your doctor or pharmacist�
The following very common complications have been
reported for the tube delivery system:
•
Leaks at the connections and leakage of gastric fluid
•
Blockade of flow of Duodopa
®
due to occlusion,
kinking and knotting of the tubing
• Dislocation of the tube (e�g�, to the stomach, resulting
in decreased treatment response)
