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Operating Manual

pfm Slide 4004 M

Sliding Microtome

Please read this operating manual 

carefully before using the instrument 

for the first time and make certain 

that you are familiar with the 

method of operation as well as the 

instrument’s controls to ensure that 

it is used correctly.

www.pfmmedical.com

Quality and Experience

Summary of Contents for Slide 4004 M

Page 1: ...d this operating manual carefully before using the instrument for the first time and make certain that you are familiar with the method of operation as well as the instrument s controls to ensure that it is used correctly www pfmmedical com Quality and Experience ...

Page 2: ...meplate Dear Customer Please read this operating manual carefully before using the instrument for the first time and make certain that you are familiar with the method of operation as well as the instrument s controls to ensure that it is used correctly All the information in this operating manual applies to the pfm Slide 4004 M Note ...

Page 3: ...he object 15 3 8 Fine automatic adjustment of the object 15 3 9 Object mounting 16 3 10 Universal cassette clamp 16 3 11 Standard object clamp 16 3 12 Object orientation 17 3 13 Exchanging the object mounting 17 3 14 Knife holder 17 3 15 Microtome blade holder 18 3 16 Adapter orientable 18 3 17 Section waste tray 18 Part 4 Working with the microtome 19 4 1 Preparing embedding and sectioning the ob...

Page 4: ...instrument If the above rule is violated pfm medical ag shall assume no liability Safety instructions 1 1 Key to symbols Caution This symbol indicates a possible danger to life and health Failing to observe these instructions can result in severe health impacts including life threatening injuries Indicates useful information Indicates a dangerous situation NOTE WARNING Manufacturer Date of manufac...

Page 5: ...rmal domestic waste It must be collected separately Permissible temperature range at the place of use 10 C 40 C Permissible temperature range for storage and transportation 10 C 50 C Permissible humidity range for storage and transportation and at the place of use 10 80 non condensing 10 C 40 C 10 C 50 C 10 80 Keep dry Fragile handle with care ...

Page 6: ...e familiar with the instrument s method of operation Before using the instrument for the first time the operating manual must be read so that the user is familiar with the method of operation and the controls This is essential to ensure proper handling NOTE The operating manual should be accessible to everyone The instrument is fitted with the following safety devices 1 4 Microtome safety devices ...

Page 7: ...and Observe all warnings Warnings on the instrument must not be removed or obscured Only use suitable accessories recommended supplied by pfmmedical If unusual noises develop please contact your responsible pfm service technician or contact pfm medical ag directly The instrument may only be opened and repaired by service technicians trained and authorised by pfmmedical No corrosive acidic or alkal...

Page 8: ...versal cassette clamp 1 11 2 12 3 13 4 6 7 5 8 9 10 Protection tray Adjusting screws for X Y object orientation with tangible zero point Clamping lever Section waste tray Section thickness adjustment Handwheel for rough adjustment Setting lever Housing 2 3 4 6 7 8 9 10 11 12 13 5 1 2 1 View of the pfm Slide 4004 M Introduction ...

Page 9: ...mple size Universal cassette clamp standard embedding cassettes Standard object clamp large sample size 45 x 60 mm Universal cassette clamp large super mega embedding cassettes Dimensions W D H 340 x 420 x 300 mm Weight 22 kg 2 2 Technical data for the pfm Slide 4004 M Introduction 2 3 Scope of delivery pfm Slide 4004 M REF 400410 Scope of delivery Base instrument 1 Protective cover Without knife ...

Page 10: ...nd the set up area The instrument should be placed on a stable vibration free table or desk The instrument must be placed on a non combustible flat surface If other instrument in the vicinity of the microtome generates vibrations these can interfere with the sectioning process Room temperature at the installation location of the instrument between 10 C and 40 C Relative humidity at the installatio...

Page 11: ...ver Turn the two adjustment screws for object orientation to the tangible zero point marked in red Insert the object clamp with the adapter paying attention to the position of the hole so that the clamping lever can later be inserted without difficulty Clamp the object clamp using the clamping lever After each change check that the clamping lever is sufficiently clamped NOTE Some object clamps are...

Page 12: ...knife holder from the side Clamp the microtome blade holder using the two clamping screws After each change check that the microtome blade holder is sufficiently clamped Assembling the knife holder 2 Knife holder Knife holder clamping lever 1 2 1 Release and completely remove the clamping lever Insert the adapter on the knife holder into the microtome Take note of the position of the hole so that ...

Page 13: ...icrotome blade is sufficiently clamped Feather microtome blade S35 1 2 Pressure plate Screw 1 2 Section waste tray The section waste tray is only attached to the pfm Slide 4004 M and can be removed at any time Inserting the microtome blade into the pfm Blade Holder Fold up the finger guard Release the clamping eccentric for the pressure plate Remove the microtome blade from the dispenser and caref...

Page 14: ...ont middle and rear end positions however the slide is not solidly blocked only lightly positioned Locking lever 1 1 Handle 1 1 160 mm The sectioning movement of the microtome is created by moving the knife slide horizontally using the handle 3 5 Setting the section thickness Scale wheel 1 1 The required section thickness is adjusted by turning the scale wheel on the left at the back of the microt...

Page 15: ...nt over the specimen after the adjustment has been made The sectioning thickness then corresponds to the set value on the section thickness adjustment 3 8 Fine automatic adjustment of the object Activation bolt 1 1 The automatic adjustment of the sectioning thickness is made after the activation bolt latch In total there are three positions of the activation bolt Position 1 the automatic fine feed...

Page 16: ...3 10 Universal cassette clamp The universal cassette clamp is a quick exchange system used for cassette mounting The lever must be pressed upwards in order to insert or withdraw the cassette WARNING Caution The contact surfaces on the cheeks of the object clamps must be free of any residual paraffin Otherwise proper clamping cannot be guaranteed The standard object clamp is used for paraffin block...

Page 17: ... the clamping lever is sufficiently clamped If it is not properly clamped vibrations etc can occur while sectioning 2 Button clearance angle adjustment Clamping screws Finger guard 1 3 1 2 3 In order to clamp the knife or microtome blade holder into the knife holder both clamping screws are unscrewed until the knife or microtome blade holder can be pushed in from the side Finally both clamping scr...

Page 18: ...e holders is available directly from pfm medical ag WARNING Caution The microtome blade must be exact ly positioned on the lay edge of the microtome blade holder otherwise vibrations will occur when cutting FEATHER Microtome blade holder type 240D The adapter orientable enables easy alignment of the object to the sectioning level over the object orientation WARNING Caution It is imperative that th...

Page 19: ...from pfm medical ag service pfmmedical com T 49 0 22369641 220 F 49 0 22369641 51 The sectioning movement over the knife slide on the pfm Slide 4004 M is made by manual forwards and backwards movement The ergonomically designed handle on the knife slide simplifies this procedure The adjustment of the selected and set section thickness on the section thickness adjustment is carried out manually by ...

Page 20: ...nife holder Check jam adjust clean Inaccurate adjustment Cross roller guide Check mechanical clearances adjust clean Vertical cross roller guide Check mechanical clearances adjust clean Section thickness device Check adjustment set No adjustment Spring pressure Adjust spring pressure No automatic adjustment Spring pressure Adjust spring pressure No manual adjustment Micrometer mechanism Disassembl...

Page 21: ...r or maintenance Repairs and maintenance work are usually carried out on site If this is not possible for any particular reason the instrument can be sent to pfm medical ag Before you send an instrument to pfmmedical for a service it must be suitably cleaned and decontaminated This also applies to instruments undergoing a service on site Contaminated instruments pose a potential health hazard for ...

Page 22: ...tutory or other contractual claims This applies in particular to any claims for compensation for damage consequential damage or costs relating to the defect The transport of the instrument to us and return transport during this period shall be at the customer s risk To assert a claim under this warranty the device concerned must be sent to us at the customer s expense and risk with a detailed desc...

Page 23: ...ys and lengthways clamping possible Object clamp to be used with orientable adapter or fixed adapter Quick release clamp system for large embedding cassettes Crossways and lengthways clamping possible Orientable version with adapter Orientable version with adapter Maximum sample size 40 x 45 mm Orientable version with adapter Quick release clamp system for all available cassettes Crossways and len...

Page 24: ...or larger samples Maximum sample size 45 x 60 mm Distance adapter object orientation 6 mm REF 010046 Suitable for all pfmmedical object clamps Distance 6 mm Accessories Knife holder REF 013000 The knife holder with finger guard is suitable for use with all conventional knives and blade holders pfm Blade Holder REF 013001 Direct fixing on the microtome with eccentric clamping Removable and easy to ...

Page 25: ...25 pfm Slide 4004 M Rev 2022 03 28 For your notes Notes ...

Page 26: ...cts IFU2004004 2022 03 28 Contact pfm medical ag Wankelstrasse 60 50996 Cologne Germany Certified according to DIN EN ISO 13485 Do you have any questions Our Customer Solutions Team will be happy to advise you service pfmmedical com 49 0 22369641 220 49 0 22369641 51 ...

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