Zeiss CIRRUS HD-OCT 500, User Manual

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Appendix
2660021169012 Rev. A 2017-12 CIRRUS HD-OCT User Manual
B-14
Table B-13: Repeatability and Reproducibility of Volume of RPE Elevations
For the area of RPE elevations, the coefficient of variation (CV) was lowest for the
measurements in the 5 mm circle of the 200x200 scan (4.9%) and highest for the
measurements in the 3 mm circle of the 200x200 scan (10.1%).
For the volume of RPE elevations, the CV was lowest for the measurements in the 5 mm
circle of the 200x200 scan (8.3%) and highest for the measurements in the 3 mm circle of
the 200x200 scan type (15.2%).
Repeatability Reproducibility
Repeatability
SD (mm
3
)
Repeatability
Limit
a
(mm
3
)
Reproducibility SD
(mm
3
)
Reproducibility
Limit
b
(mm
3
)
CV
c
%
200x200 Scan
3mm Circle 0.0117 0.0327 0.0122 0.0341 15.2%
5mm Circle 0.0098 0.0275 0.0106 0.0298 8.3%
512x128 Scan
3mm Circle 0.0074 0.0206 0.0084 0.0235 12.0%
5mm Circle 0.0088 0.0245 0.0103 0.0288 11.4%
a. Repeatability Limit is the upper 95% limit for the difference between repeated results. Per ISO 5725–1 and ISO 5725–6, Repeatability Limit = 2.8
x Repeatability SD.
b. Reproducibility Limit is the upper 95% limit calculated for the difference between individual measurements using different operators and instru-
ments. Per ISO 5725–1 and ISO 5725–6, Reproducibility Limit = 2.8 x Reproducibility SD.
c. CV = Coefficient of variation = SD ÷ Mean.