Appendix
2660021169012 Rev. A 2017-12
CIRRUS HD-OCT User Manual
B-6
Table B-4: Difference between CIRRUS HD-OCT and Stratus OCT for the Central
Subfield Mean Thickness for each of the Six Categories.
Repeatability
The repeatability of CIRRUS HD-OCT retinal thickness measurements varies with pathology.
shows the repeatability standard deviation for each disease category for the
central subfield average thickness. This is the expected standard deviation between two
scans acquired and analyzed using CIRRUS 3.0.
Repeatability can be improved by ensuring that two scans are registered to each other, as
when the Macular Change Analysis is used. Repeatability can also be improved using the
Macular Thickness Analysis in CIRRUS 4.0 when the fovea is correctly identified and used
as the reference point for subfield average thickness calculations. These repeatability
improvements are shown in
. It is important to note that the algorithm to find
the fovea may fail in certain disease cases, as is shown in
. The user should
always review the location of the fovea, and adjust it as necessary (see
for instructions on how to do this).
Repeatability when registration and fovea placement are performed is better than 9
μ
m for
all pathologies, which implies a coefficient of variability (repeatability standard deviation
divided by mean thickness) of 3.3% or better. Coefficient of variability is better than 1% for
normals.
Mean (SD) Difference CIRRUS – Stratus (
μ
m)
N
CIRRUS
Stratus
Difference
1 – AMD
63
271.3 (60.6)
217.7 (54.2)
53.6 (35.0)
2 – DR
39
356.6 (118.7)
316.6 (135.8)
40.0 (47.1)
3 – VRI
45
386.3 (128.0)
342.5 (125.0)
43.8 (35.9)
4 – Other
53
310.6 (99.5)
268.9 (101.6)
41.7 (47.1)
5 – ME
35
351.1 (140.3)
305.7 (127.9)
45.5 (45.3)
6 – Normal
48
256.1 (18.6)
196.7 (18.6)
59.4 (11.7)
Summary of Contents for CIRRUS HD-OCT 500
Page 1: ...2660021156446 B2660021156446 B CIRRUS HD OCT User Manual Models 500 5000 ...
Page 32: ...User Documentation 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 2 6 ...
Page 44: ...Software 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 3 12 ...
Page 58: ...User Login Logout 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 4 14 ...
Page 72: ...Patient Preparation 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 5 14 ...
Page 110: ...Tracking and Repeat Scans 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 6 38 ...
Page 122: ...Criteria for Image Acceptance 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 7 12 ...
Page 222: ...Overview 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 9 28 ...
Page 256: ...Log Files 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual 11 18 ...
Page 308: ...Appendix 2660021169012 Rev A 2017 12 CIRRUS HD OCT User Manual A 34 ...
Page 350: ...CIRRUS HD OCT User Manual 2660021169012 Rev A 2017 12 I 8 ...
Page 351: ...CIRRUS HD OCT User Manual 2660021169012 Rev A 2017 12 ...