E–Material Safety Data Sheet
Phaser™ 3450 Laser Printer
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HAZARDOUS DECOMPOSITION PRODUCTS: During a fire, toxic gases may be generated
by thermal decomposition or combustion. Avoid breathing smoke.
SECTION 11 - TOXICOLOGICAL INFORMATION
This material has been evaluated by Xerox Corporation. The toxicity data noted below is based
on test results of similar toners.
Oral LD50: >5 g/kg (rats), practically non-toxic
Dermal LD50: > 5 g/kg (rabbits), practically non-toxic
Inhalation LC50: > 2 mg/l (rats; 4 hour exposure), practically non-toxic
Eye Irritation: Not an irritant
Skin sensitization: Not a sensitizer
Skin irritation: Not an irritant
Human Patch: Non-irritating, non-sensitizing
Mutagenicity: No mutagenicity detected in Ames assay
Carcinogens: None present
Additional Information: The results obtained from a Xerox sponsored Chronic Toner
Inhalation Study demonstrated no lung changes in rats for the lowest (1 mg/m3) exposure level
(ie., the level most relevant to potential human exposure). A very slight degree of fibrosis was
noted in 25% of the animals at the middle (4 mg/m3) exposure level, while a slight degree of
fibrosis was noted in all the animals at the highest (16 mg/m3) exposure level. The findings
are attributed to “lung overloading”, a generic response to excessive amounts of any dust
retained in the lungs for a prolonged period. This study was conducted using a special test
toner to comply with EPA testing protocol. The test toner was ten times more respirable than
commercially available Xerox toner and would not be functionally suitable for Xerox
equipment.
SECTION 12 - ECOLOGICAL INFORMATION
Aquatic LC50: > 1000 mg/l (fathead minnows); non-toxic
SECTION 13 - DISPOSAL CONSIDERATIONS
