Waters Micromass ZQ 2000, Operator'S Manual

Page: 44 / 133

Tuning 44
3
Source and Desolvation Temperatures
The Source and Desolvation temperature settings control desolvation for a specified flow
rate.
Table 3-2 gives temperature ranges for specific flow rates.
3.2.1 Specifying Parameter Settings on the ES+ Source Page
1. Click (API Gas) in the Tune window to toggle the nitrogen flow to On.
2. Make sure the instrument is operating, noting whether peak activity appears in the
Tune window’s Peak Display area (
Figure 3-3 ). If the instrument is not operating
(indicated by no peaks), click Press for Operate .
Source temperature See Table 3-2 .
Desolvation
temperature See Table 3-2 .
Desolvation gas flow Optimizes gas flow depends on mobile phase composition and
flow rate (>100 L/hr).
Cone gas flow Helps reduce adduct ions and keep the sample cone clean (50
to150 L/hr).
Table 3-2 Source and Desolvation Temperature Settings
HPLC Flow
Rate (µL/hr)
Source Temperature
o
C Desolvation Temperature
o
C
<100 80 to 100 100 to 350
100 to 250 100 to 130 350 to 400
250 to 1000 130 to 150 400 to 450
STOP
Attention: You must toggle API gas to Off before reopening the nitrogen
supply once it has been shut off. Otherwise, the sudden inrush of gas can
damage the flow meter.
Table 3-1 ES+ Source Page Parameters (Continued)
Parameter Description