Normal Floor of the Mouth
Sometimes the area around the sub-lingual gland can be well vascularized, and can lead to a variable
degree of loss of fluorescence.
Normal Variation - Oropharynx with Numerous Lymphoid Aggregates
Sometimes the oropharynx can host varying numbers of lymphoid aggregates, which, due to tissue structure,
display a pronounced loss of fluorescence.
Irritation and Inflammation
The buccal mucosa is a common site for irritation and consequent inflammation; inflammation always shows a distinct loss of
fluorescence because of increased blood content.
Figure 2. Representative examples of the appearance of healthy vs. suspicious oral tissue under both incandescent light and
VELscope examination.
