Thermo Scientific
MS/ETD System Getting Started Guide
51
7
Troubleshooting
The MS/ETD System uses the following consumables:
• Filament
• Fluoranthene
• Ion volume
After a period of time, you might need to replenish the ETD fluoranthene reagent, replace the
filament, and clean or replace the ion volume. As the consumables are depleted, the ETD
reagent
m/z
peak intensity diminishes (
m/z
= 202 in negative polarity mode). Periodically
checking this peak intensity is a good way to monitor the ETD module consumables. To view
the ETD reagent
m/z
signal, follow the procedure in
“Turning On the Reagent Ion Source”
lists some ETD module problems, their causes, and their possible solutions.
Tip
Expect the filament and ion volume to last for about 400 to 500 hours of operation,
and a vial of fluoranthene reagent to last for several months or more.
