Terumo BCT Quantum Cell Expansion System, Operator'S Manual

Page: 82 / 204

Outlet
Outlet designates a pathway from the bioreactor to an outlet destination during a task or a step of a task.
The outlet destination is either the bag attached to the outlet line or the harvest bag. The following list
describes all the possible setting options for Outlet:
•
EC Outlet: allows fluid to flow from the EC side of the bioreactor into the bag that is attached to the
outlet line.
• IC Outlet: allows fluid to flow from the IC side of the bioreactor into the bag that is attached to the
outlet line.
• IC and EC Outlet: allows fluid to flow from both the IC side and the EC side of the bioreactor into
the bag that is attached to the outlet line.
• Harvest: allows fluid to flow from the IC side of the bioreactor into the harvest bag.
• Synchronization: The system synchronizes the IC and EC inlet pumps with the IC and EC outlet
valves and alternates between the following two states every five minutes:
1. The IC inlet pump turns on and the IC outlet valve opens while the EC outlet valve closes and
the EC inlet pump turns off. (In order to achieve an average flow rate equal to the entered
value, the actual IC inlet rate is double the value that has been set.)
2. The EC inlet pump turns on and the EC outlet valve opens while the IC outlet valve closes and
the IC inlet pump turns off. (In order to achieve an average flow rate equal to the entered value,
the actual EC inlet rate is double the value that has been set.)
Table 6-4 describes the positions of the valves for each Outlet setting.
Table 6-4: Valve positions for each Outlet setting
Outlet setting
IC outlet valve
position
EC outlet valve
position
Harvest valve position
EC Outlet closed open closed
IC Outlet open closed closed
IC and EC Outlet open open closed
Harvest closed closed open
Synchronization alternates between open
and closed alternates between open
and closed closed
Selecting an Outlet
The following instructions explain how to select an Outlet setting.
From the Setup screen:
1. Touch
Outlet
.
A menu of Outlet settings appears, and
Outlet
changes to black, as shown in Figure 6-4.
Outlet
Quantum
®
Cell Expansion System • Operator's Manual for Software Version 2.1 6-9