Please scroll for additional Important Safety Information, and click for
, and discuss with your healthcare provider.
What is HYQVIA?
• HYQVIA is a liquid medicine containing immune globulin and Recombinant Human
Hyaluronidase. HYQVIA contains IgG antibodies, collected from human plasma donated
by healthy people. The antibodies help your body to fight off bacterial and viral
infections. The hyaluronidase part of HYQVIA helps more of the immune globulin get
absorbed into the body to fight infection.
• HYQVIA is indicated for the treatment of Primary Immunodeficiency (PI) involving the
humoral immune system in adults.
• Safety and efficacy of chronic use of Recombinant Human Hyaluronidase in HYQVIA
have not been established in conditions other than PI.
• HYQVIA is infused under the skin (subcutaneous).
• If you and your healthcare professional decide that home self-infusion of HYQVIA
is right for you, then be sure you get instructions and training from your healthcare
professional before using HYQVIA at home.
Important Safety Information
What is the most important information that I should know about HYQVIA?
•
HYQVIA can cause blood clots.
•
Call your healthcare professional if you have pain, swelling, warmth,
redness, or a lump in your legs or arms, other than at the infusion site(s),
unexplained shortness of breath, chest pain or discomfort that worsens on
deep breathing, unexplained rapid pulse, numbness or weakness on one
side of the body.
• Your healthcare professional may perform blood tests regularly to check your IgG level.
• With your consent, your healthcare professional may provide blood samples to Shire plc,
to test for antibodies that may form against the hyaluronidase part of HYQVIA.
• Do not infuse HYQVIA into or around an infected or red swollen area because it can
cause infection to spread.
• Talk to your healthcare professional if you become pregnant. Women who become
pregnant during HYQVIA treatment are encouraged to enroll in the HYQVIA Pregnancy
Registry by calling Medical Information at 1-866-424-6724.
Who should not take HYQVIA?
Do not take HYQVIA
if you:
• Are allergic to IgG, hyaluronidase, other blood products, or human albumin
(in the hyaluronidase solution).
• Have IgA deficiency with antibodies to IgA.