OvaCue Mobile Fertility Monitor, Owner'S Manual

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As the dominant follicle matures, the amount of estrogen produced in your body increases. At the
same time, luteinizing hormone (LH) is produced and stored in the anterior pituitary gland. Just
prior to ovulation, the anterior pituitary gland secretes a surge of LH, which causes the wall of
the dominant follicle to weaken and rupture, thereby releasing the egg and propelling it into the
opening of the nearby fallopian tube.
Once the egg is released from the follicle, the follicle cells transform into the corpus luteum, a
glandular structure that secretes large amounts of progesterone. If the egg is fertilized (which
must occur within 24 hours after ovulation), increasing amounts of progesterone are released.
Progesterone acts to build the uterine lining for implantation of a fertilized egg and prevents
menstruation. If conception does not occur, the corpus luteum will disintegrate towards the end of
the menstrual cycle, progesterone levels will drop rapidly, and menstruation will occur.
By tracking changes in the concentration of electrolytes in your saliva, OvaCue Mobile detects
the hormonal changes that coincide with the maturation of the dominant follicle, and uses this
information to predict the days you will be most fertile. Using the data collected with the vaginal
sensor, OvaCue Mobile detects the surge in estrogen that occurs just prior to ovulation, and the
shift to progesterone dominance that occurs at ovulation. This information allows OvaCue Mobile
to help confirm the date of ovulation.