Gambro Cobe Spectra, Essentials Manual

Page: 32 / 245

Introduction
2-6 COBE
®
Spectra™ Apheresis System • Essentials Guide
Pressure Sensors
The Spectra system has three pressure sensors:
Access pressure sensor : Diaphragm-type sensor with transducer that
monitors negative pressure from the donor/patient access site. This
sensor checks for low access pressure.
Centrifuge pressure sensor : Strain gauge sensor that measures pressure
beyond the inlet pump. This sensor monitors for high centrifuge
pressure (caused by an air block or occluded tubing).
Return pressure sensor : Diaphragm-type sensor with transducer that
monitors positive pressure above the return air chamber. This sensor
checks for high return pressure. During Single-Needle procedures, this
sensor monitors the pressure in the Single-Needle bag.
Optical Sensors
The Spectra system has two optical sensors:
Collect concentration monitor (CCM) : Monitors the density in the
collect line. During ELP, LRS, and LRST procedures, the CCM helps
the system
•
Estimate the current platelet yield at any time during the procedure.
•
Calculate the platelet concentration in the collection bag at the end
of the procedure (ELP procedures only).
•
Predict the platelet yield for the end of the procedure (ELP
procedures only).
•
Detect RBC spillovers greater than 3% hematocrit, and protect the
platelet product by diverting the RBCs to the donor.
•
Monitor the collect line for events which can cause cellular
contamination (LRS and LRST procedures only).
.
During an AutoPBSC procedure, the CCM monitors Harvest phases
and RBC spillovers. During a TPE procedure, the CCM detects RBC
spillovers.
RBC detector (located in the same housing as the RBC/plasma line
valve): Monitors the line in the RBC/plasma line valve for RBCs at the
beginning of the apheresis procedure. When it sees RBCs in the line, it
closes the waste divert valve and opens the return line valve.
If the detector does not see RBCs when the system reaches the default
inlet volume, the “NO RBCs DETECTED!” alarm occurs (see
page 12-41 for more information). Table 2-1 shows the default inlet
volume for the different procedures.
Air Sensors
The Spectra system has three ultrasonic air sensors:
Inlet air detector : Detects air in the inlet air chamber, stops the pumps
to prevent air from entering the centrifuge, and closes the return line
valve to prevent air from flowing to the donor/patient.
Return air detector : Detects air in the return air chamber, stops the
pumps, and closes the return line valve to prevent air from flowing to the
donor/patient.
Anticoagulant (AC) level detector : Detects air in the AC line.
Note: The CCM is not accurate during platelet depletion
procedures.
Table 2-1: Default inlet volumes
Disposable Tubing Set Default Inlet Volume
ELP, LRS, LRST 120 mL
TPE, AutoPBSC, WBC 150 mL