5
Covaris
Part Number: 010516 Rev B | March 2020
ML230 Setup & Instruction Manual
Table of Contents
1. Introduction ...................................................................................................................................................................................... 6
1.1 Overview of the Instruction Manual ................................................................................................................................. 6
1.2 The ML230 and the Covaris Process ................................................................................................................................ 6
2. Installation and Setup ..................................................................................................................................................................... 7
2.1 Unpacking the System ......................................................................................................................................................... 7
2.2 Assembly ................................................................................................................................................................................ 7
2.3 Levelling the ML230 Instrument ........................................................................................................................................ 12
2.4 ML230 Software ................................................................................................................................................................... 13
2.5 Starting the ML230 Instrument ......................................................................................................................................... 14
3. Operation .......................................................................................................................................................................................... 15
3.1 General Overview ................................................................................................................................................................. 15
3.2 Preparing the ML230 for Use ............................................................................................................................................. 16
3.3 ML230 Water Control .......................................................................................................................................................... 19
3.4 Loading the Sample .............................................................................................................................................................. 19
3.5 Running a Method ................................................................................................................................................................ 21
3.6 Instrument Light .................................................................................................................................................................... 21
3.7 User Maintenance .................................................................................................................................................................
22
3.8 Shutdown Procedure ............................................................................................................................................................
23
4. Using a Pre-installed Method ........................................................................................................................................................ 24
4.1 DNA Shearing Protocols ...................................................................................................................................................... 24
5. Create and Edit Methods ............................................................................................................................................................... 25
5.1 Create New Method ............................................................................................................................................................. 25
5.2 Modify Existing Method ......................................................................................................................................................
30
6. SonoLab™ Application Software ....................................................................................................................................................
32
6.1 Method Tab ............................................................................................................................................................................
32
6.2 Schedule Tab .......................................................................................................................................................................... 34
6.3 History Tab ............................................................................................................................................................................. 36
6.4 About Tab ............................................................................................................................................................................... 37
6.5 Admin Tab ............................................................................................................................................................................... 38
7. System Specifications ...................................................................................................................................................................... 42
8. Troubleshooting ............................................................................................................................................................................... 43
9. Appendix ........................................................................................................................................................................................... 44
Appendix A: M-Series Site or Transport Preparation ............................................................................................................. 44
Appendix B: Updating SonoLab Software ............................................................................................................................... 44
Appendix C: Replacing the ML230 Particle Filter Element (PN 500679) ..........................................................................45