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Normal values and indications for weaning (adults)
Parameter
Normal range
Indications for
weaning
Respiratory rate
10 to 20 breaths/minute
< 30 B/min
△
Esophageal pressure
5 to 10 cmH
2
O
< 15 cmH
2
O
Tidal volume
7 to 10 mL/kg
> 5 mL/kg
△
Minute ventilation
5 to 10 Liters/min
< 10 L/min
WOB
P
3 to 0.6 Joules/Liter
< 0.75 J/L
△
Pressure time index
0.05 to 0.12
< 0.15
△
Airway resistance
2 to 5 cmH
2
O/L/s
< 15 cmH
2
O/L/s
Lung compliance
50 to 100 mL/cmH
2
O
> 25 mL/cmH
2
O
Maximum inspiratory
-30 cmH
2
O low effort
> -20 cmH
2
O
△
Pressure (MIP)
-140 cmH
2
O high effort
Auto PEEP
0
< 3 cmH
2
O
Respiratory drive P0.1
2 to 4 cmH
2
O
< 6 cmH
2
O
△
f/VT
60 to 90
< 105
Pressure time
200 to 300 cmH
2
O sec/min
Product (PTP)
Ti/TTOT
0.3 to 0.4
Parameter
Acceptable range
SaO
2
> 90% on FlO
2
of < 40%
P(A - a) O
2
on
FlO
2
of 100%
< 350 mmHg
PaO
2
/FlO
2
> 200 mmHg
Qs/Qt
< 20%
Vd/Vt
< 0.6
Heart rate
> 70 and < 120 bpm
Mean blood pressure
> 70 and < 110 mmHg