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Biotage

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 P 48 User Manual | © Biotage 2017

System Description

P 48 is a positive pressure manifold designed to 
process SPE columns using a pressurized gas source.

Load the Columns

P 48 units are compatible with all commonly 
used 1 mL, 3 mL and 6 mL tabless columns used for sample 
preparation.

The handgrip on the front of the platform helps you to slide 
the platform with the racks forward and backward under the 
manifold. Stack the column rack onto the waste bin rack and 
populate with the required number of columns. Each column will 
be pressurized equally even if columns are omitted.

Push the platform and populated rack assembly to the back 
of the track until it reaches the stop point (under the upper 
manifold). To lower the manifold, press down on the two rocker 
switches simultaneously and hold for approximately 3 seconds. 
This will activate the upper manifold and it will self-adjust to 
an appropriate height by lowering and compressing. If you let 
go too soon, the upper manifold will rise up and you can simply 
repeat by pressing down on the rocker switches and holding 
them again for approximately 3 seconds.

To release the column rack, press up on both rocker switches, 
then slide the assembly forward.

Note:

 The upper manifold is powered by the gas source and the 

speed is preset and not adjustable.

IMPORTANT:

 An important safety feature of the unit is the 

requirement to hold both rocker switches for approximately 
3 seconds simultaneously to lower the manifold. This is to keep 
hands clear of moving parts during compression.

System Description

Figure 2.

 Lower the manifold by pressing down on the two rocker switches 

simultaneously for approximately 3 seconds.

Summary of Contents for PRESSURE+ 48

Page 1: ...Biotage PRESSURE 48 User Manual ...

Page 2: ...y and Liability 1 Service 1 Equipment Safety Standards 1 Labels 1 Safety Requirements 2 Installation 2 Site Requirements 2 Unpack and Install 4 System Description 4 Load the Columns 5 Flow Control 6 Operation 6 Step by Step Instructions 8 Maintenance 8 Replace the Sealing Gasket 8 Clean 9 General Information 9 Consumables and Accessories 9 Manufacturer 9 Contact Us ...

Page 3: ... 8 It is the responsibility of the customer to inform Biotage 1 Point Support representatives if the equipment has been used with hazardous biological radioactive or toxic samples and or solvents prior to any service being performed When returning equipment to Biotage this should be done in accordance with the material return procedures supplied separately by Biotage Equipment Safety Standards PRE...

Page 4: ...s achieved by a regulator positioned between the gas source and the unit The supplied gas supply installation kit PPM GA provides the parts necessary to make the connection between the gas regulator and the unit Minimum pressure 60 psi 4 1 bar Maximum pressure 100 psi 6 9 bar Optimum pressure 80 psi 5 5 bar Unpack and Install Warning The total weight of the package including the unit is 22 kg 48 l...

Page 5: ...with Inserts 3 1 413247 User Manual 1 Column Racks and Collection Racks Note Column racks and collection racks must be purchased separately see the list of racks below Part Number Description PPM A48 1RCK PRESSURE 48 SPE Column Rack 1 mL PPM A48 3RCK PRESSURE 48 SPE Column Rack 3 mL PPM A48 6RCK PRESSURE 48 SPE Column Rack 6 mL PPM A48 1275 PRESSURE 48 Collection Rack 12 x 75 mm PPM A48 13100 PRES...

Page 6: ... the manifold press down on the two rocker switches simultaneously and hold for approximately 3 seconds This will activate the upper manifold and it will self adjust to an appropriate height by lowering and compressing If you let go too soon the upper manifold will rise up and you can simply repeat by pressing down on the rocker switches and holding them again for approximately 3 seconds To releas...

Page 7: ...icated on the label never turn the rotometer completely off Seating the needle valve into its orifice can damage the unit Figure 3 The rotometer A flow control switch B Adjustable Flow regulator C and Maximum Flow regulator D Maximum Flow Rate 0 to 100 psi Recommended for column washing drying etc By turning the flow control switch B to the right to the Maximum Flow position gas is introduced at t...

Page 8: ...ORTANT As indicated on the label never turn the rotometer completely off Seating the needle valve into its orifice can damage the unit 9 Lower the manifold by pressing down on the two rocker switches simultaneously for approximately 3 seconds see Figure G 10 When all liquids have passed through the columns turn the flow control switch to the OFF position See Figure H 11 Raise the pressure manifold...

Page 9: ...7 Operation B C D E G H J I F ...

Page 10: ... the manifold using ethanol 8 Remove the backing of the replacement sealing gasket 9 Align the holes on the new sealing gasket with the manifold s holes and adhere the seal 10 Fasten the manifold with the sealing gasket facing down to the standoffs using the two hex screws and the hex key Note The adhesive on the sealing gaskets is volatile and cannot be stored for long periods of time at room tem...

Page 11: ...100 mm Test Tube Uncapped 1000 C40708 16 x 100 mm Test Tube Uncapped 1000 PPM A48 WST Waste Bin Inserts 3 PPM A48 WSTRCK Waste Bin Rack with Inserts 3 1 PPM A48 GSKT Sealing Gasket 48 positions also contains a hex key 1 PPM GA PRESSURE Gas Supply Adaptor for all models 6 of 1 8 i d polyethylene tubing and 1 8 and 1 4 NPT connectors 1 For a complete list please visit our website www biotage com Man...

Page 12: ...Toll Free 1 800 446 4752 Fax 1 704 654 4917 Order Tel 1 704 654 4900 Order Fax 1 434 296 8217 ordermailbox biotage com Support Tel 1 800 446 4752 Outside US 1 704 654 4900 us 1 pointsupport biotage com JAPAN Tel 81 3 5627 3123 Fax 81 3 5627 3121 jp_order biotage com jp 1 pointsupport biotage com CHINA Tel 86 21 2898 6655 Fax 86 21 2898 6153 cn_order biotage com cn 1 pointsupport biotage com KOREA ...

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