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Gene Explorer Thermal Cycler Operation Manual                       

Chapter Five Fault Analysis and Troubleshooting 

 

23

 

 

Chapter Five Fault Analysis and Troubleshooting

 

The  chapter  mainly  introduces  possible  faults  of  the  instrument,  cause  analysis  and 

troubleshooting. 

1 Fault analysis and troubleshooting 

No. 

Fault   

Cause analysis 

Troubleshooting   

After the power switch is 
turned  on,  the  display 
screen doesn’t work.     

Disconnecting power supply 

Check  and  connect  the 
power supply   

Burned fuse 

Replace  fuse  (250V  12A 
Ф5x20)   

Damaged switch 

Replace switch 

Others   

Contact 

supplier 

or 

manufacturer 

During  file  running,  it 
shows 

“Err 

code: 

0x**0000***, 

and 

prompts  “Please  Contact 
the Manufacturer” 

Module  sensor  damage  or  loose 
contact 

Contact 

supplier 

or 

manufacturer 

Radiator  sensor  damage  or  loose 
contact 
Hot  lid  sensor  damage  or  loose 
contact 

Evident 

change 

of 

module  temperature  rise 
rate 

or 

imprecise 

temperature control   

Blocked ventilation holes   

Remove 

the 

blocking 

objects 

on 

ventilation 

holes   

Loose connecting line   

Open  the  shell  and  check 
the 

connecting 

line; 

tighten  the  screw  of  the 
terminal  block  if  it  is 
loose. 

Damaged TEC 

Contact 

supplier 

or 

manufacturer 

Evident  slowing  module 
temperature  fall  rate  or 
failure  to  fall  below 
ambient temperature   
 

Ambient  temperature  or  humidity  is 
too 

high, 

and 

exceeds 

using 

condition of the instrument   

Please  properly  adjust 
ambient  temperature  and 
humidity   

Damaged TEC 

Contact 

supplier 

or 

manufacturer 

Damaged or un-working fan   

Temperature 

not 

changing 

Damaged temperature sensor 

Contact 

supplier 

or 

manufacturer 

Damaged TEC 

The module fails to heat   

On 

system 

parameter 

setting 

interface,  hot  lid  status  is  set  as 
“OFF”. 

Set  the  hot  lid  status  as 
specific 

temperature 

value   

Temperature  control  time  on  file 
editing  interface  is  set  as  “--:--”, 
leading  to  automatic  turning  off  of 
hot lid   

Set  temperature  control 
time in digital form     

Loose connector 

Contact 

supplier 

or 

Summary of Contents for GE-48DS

Page 1: ...GeneExplorer Thermal Cycler Instruction for Use GE 96G GE 384G GE 4I GE 48D GE 48DS GE 48DG GE 96S Note Please understand that no further notice will be given for any Hangzhou Bioer Technology Co Ltd...

Page 2: ...ghts reserved Without prior written approval from Hangzhou Bioer Technology Co Ltd any part of the document shall not be copied re produced or translated into other language File No BYQ56170000000ESM...

Page 3: ...nsequences arising from user s failure for abiding by the following requirements Attention The instrument is Type I equipment in line with GB4793 1 standard with protection level of IP20 The instrumen...

Page 4: ...urce such as close to water pool or water pipe and the place should be well ventilated and free from corrosive gas or high magnetic field interruption Don t place the instrument in moisty or dusty are...

Page 5: ...has left the factory in a perfectly safe condition The instrument meets the requirements of the Regulation EU 2017 746 of the European Parliament and of the Council of 5 April 2017 on in vitro diagnos...

Page 6: ...ring instrument operation or within a certain period after the program ends B Other symbols on the packaging Date of manufacture Indicates the date when the medical device was manufactured RoHS Restri...

Page 7: ...cal devices Quality management systems Requirements for regulatory purposes If the instrument is installed in the required working environment there is no need to calibrate or correct the temperature...

Page 8: ...f warranty Attention After opening the packaging box immediately check the objects contained therein based on the packing list In case of any object damage or missing please immediately contact the su...

Page 9: ...AM 8 2 CHECK BEFORE TURNING ON THE INSTRUMENT 9 3 TURN ON THE INSTRUMENT 9 CHAPTER FOUR OPERATION INSTRUCTIONS 10 1 TURN ON THE INSTRUMENT 10 2 PCR PROGRAM EDITING 12 2 1 SETTING OF PROGRAM SECTION 13...

Page 10: ...ler Instruction for Use Chapter One Introduction 2 FURTHER NOTICE WILL BE GIVEN FOR ANY MODIFICATION 25 APPENDIX 2 VALUE AND MEANING OF SET PARAMETERS 26 APPENDIX 3 PRODUCT EMC STATEMENT 28 APPENDIX 4...

Page 11: ...cytology virology oncology genetic epidemiology forensic pathology and flora and fauna immunology it has accomplished outstanding achievements and become a milestone of contemporary molecular biology...

Page 12: ...n continue to complete the program unfinished Hot lid can adjust height and pressure based on actual using condition to adapt to different reaction tubes and effectively prevent reagent evaporation an...

Page 13: ...GeneExplorer Thermal Cycler Instruction for Use Chapter One Introduction 5 6 Service life of Thermal Cycler Service life of Thermal Cycler is 5 years from the date of instrument installation...

Page 14: ...he above requirements Pay special attention to reliable grounding of the power line 2 Transport and storage condition Ambient temperature 20 C 55 C RH 80 3 Basic parameters The parameters of the modul...

Page 15: ...imum number of editable sections is 10 maximum number of steps is 100 maximum number of loop is 99 available for secondary nesting gradient temperature range is 1 30 Ladder Temperature range 0 1 6 2 f...

Page 16: ...miliar with the contents in the chapter before turning on the machine 1 Structural schematic diagram The structural parts of the instrument include heating module hot lid power switch module including...

Page 17: ...nt Turn on the power switch switch to the position of and then the instrument will carry out self test which will take about 20s please wait patiently If the self test has discovered no problems the m...

Page 18: ...upplier Attention If the sample volume of your experiment is less than the number of cone holes of the module please evenly distribute the test tubes to ensure stable press of the hot lid on the test...

Page 19: ...Operation Instructions 11 Picture for GE 96G Picture for GE 48DS Picture of Model GE 384G GE 4I GE 96S would show the module type with 384G plate and 96V respectively Press the icon New Experiment to...

Page 20: ...em Settings During operation instrument operation status is displayed on the main interface and click to enter the interface of operation monitoring When operation is stopped click to enter the interf...

Page 21: ...and Add Click Insert a new section will be added before the section selected and lighting up Click Add a section will be added to the end of the program Click Delete to delete the section selected 2...

Page 22: ...op On the interface of PCR program setting click Loop and it will prompt interface 1 1 select the starting and ending sections of the loop click Determine and it will prompt the setting box 1 2 for lo...

Page 23: ...e increase or decrease for each loop changes the positive and negative of data Extended time time increase for each loop Speed ramp rate Gradient gradients temperature refers to the temperature differ...

Page 24: ...le name to save the file Files saved can be found under Open Experiment 3 Run program Before running experiment set up hot lid temperature reaction volume temperature control mode and control mode on...

Page 25: ...will display the temperature of each module 3 1 Temperature control mode Control Mode represents the default temperature control mode after the system is turn on and it includes two modes of Block and...

Page 26: ...ach the set temperature more quickly If setting time equal to that of Block mode the actual time for reagent reaching set temperature is obviously extended see the figure below for the relation betwee...

Page 27: ...rmal Cycler Operation Manual Chapter Four Operation Instructions 19 New Experiment Click to enter into user management Press Function to delete or rename user Select user to export to USB flash disk C...

Page 28: ...structions 20 Press Function to delete or rename file Select file to export to USB flash disk 5 System settings Click System Settings on the main interface to enter the interface of setting which incl...

Page 29: ...e access 3 Hot lid related 4 Time and date set instrument time and it will display on the lower right corner of the main interface 5 Instrument part use time 6 Dairy 7 About instruments 8 Tm calculati...

Page 30: ...er Thermal Cycler Operation Manual Chapter Four Operation Instructions 22 6 2 Driver upgrade File Copy to USB flash disk GeneExplorer location Enter into System Settings about instruments select drive...

Page 31: ...perature rise rate or imprecise temperature control Blocked ventilation holes Remove the blocking objects on ventilation holes Loose connecting line Open the shell and check the connecting line tighte...

Page 32: ...low 0X Left sensor Right sensor Reserve d Reserve d Reserve d Reserve d Single module hot lid double modu le hot lid A Double modul e hot lid B Radiato r 0 normal 1 open circuit alarm 2 short circuit...

Page 33: ...Gene Explorer Thermal Cycler Operation Manual Appendix 1 25 Appendix 1 Wiring Diagram the diagram is only for reference and please understand that no further notice will be given for any modification...

Page 34: ...ime Time increase for each cycle m ss 0 00 9 59 6 Cycle1 Number of the cycle 1 5 Cycle1 00 From 00 to 00 00 Times of the cycle 1 99 From 00 Starting section of the cycle X any existing section number...

Page 35: ...ut 3 after reaching set temperature reagent temperature can get close to the set temperature more quickly see Fig 2 13 Sample Volume Sample volume ul 10 200 14 Holid Hot lid off Off Hot lid on 30 110...

Page 36: ...formance criterion Shell Electrostatic discharge ESD GB T 17626 2 Air discharge 2kV 4kV 8kV Contact discharge 2kV 4kV B Radiation magnetic field GB T 17626 3 3V m 80MHz 2 0GHz 80 AM A Rated PFMF a GB...

Page 37: ...equipment with DC power input port using AC DC power adapter test should be conducted on AC input port of AC DC power adapter specified by the manufacturer If there is no specific requirement typical...

Page 38: ...Model Specification Unit QTY Remark 1 Power line with shield magnetic ring clamp 250V10A String 1 Accessory 2 Fuse 250V12A 5 20 Piece 2 Accessory 3 WiFi Module Piece 1 Accessory 4 Ethernet Patch Cable...

Page 39: ...g District 310053 Hangzhou PEOPLE S REPUBLIC OF CHINA Website www bioer com cn Tel 86 571 85800535 87774558 Fax 86 571 85800537 87774559 E mail instrument bioer com cn MedNet EC REP GmbH Borkstrasse 1...

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