BIO RAD ZE5, User Manual

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Fluidics System
Microbes in the fluidic lines potentially increase background noise in the data, especially in the scatter
channels, and can clog the lines or flow cell if the buildup becomes significant.
System Cleaner Bottle
The system cleaner bottle, which has a blue cap, contains a system cleaning reagent. During the
shutdown process, cleaner is delivered to the portions of the fluidics system that are in contact with
sample, such as the flow cell and sample line. This process minimizes sample buildup over time and
preserves the integrity of the system.
For more information, see:
n Shutting Down on page 161
n
Cleaning Solutions on page 321
Fluidics Filters
All of the onboard reagents are filtered through 0.2 µm capsule filters that remove particulates from the
fluid before it is circulated through the system. This helps reduce background noise, especially in the
scatter channels, and helps prevent microbes from entering a major portion of the fluidics path. These
filters are mounted behind a panel on the right side of the instrument.
Important: Replace filter cartridges on a regular basis. Filter replacement is part of the annual
Bio-Rad Service preventive maintenance visit. For additional information, see Chapter 12,
Maintenance .
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