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Functional Description
API Source _________________________________________________________________

1-14

___________________ LCQ Deca XP Plus Hardware Manual ________________

API Stack

The API stack consists of the components of the API source that are held 
under vacuum, except for the atmospheric pressure side of the spray shield, 
and the components of the ion sweep. The API stack includes the spray shield, 
ion sweep cone, spray cone, ion transfer capillary, heater assembly, vent 
prevent ball valve, extension mount, tube lens, skimmer, and tube lens and 
skimmer mount.   See Figure 1-7. The same API stack is used for ESI, APCI, 
and NSI ionization techniques.

The spray shield is a stainless steel cylindrical vessel that, in combination 
with the ESI, APCI, or NSI flange, and the spray cone, forms the atmospheric 
pressure region of the API source (also called the spray chamber). The spray 
shield inserts into an opening in the vacuum manifold and serves as a base for 
the API stack. An opening in the bottom of the spray shield serves as a drain 
for waste liquid. Two flange retainer bolts on the ESI, APCI, or NSI flange 
secure the flange to the atmospheric pressure side of the spray chamber.

The ion sweep cone is the outer stainless steel cone that is held by the spray 
cone. The spray cone is a stainless steel cone that fastens to the spray shield. 
The ion sweep cone is usually placed in one of two positions on the spray 
cone. This allows the distance between the opening of the ion sweep cone and 
the opening of the ion transfer capillary (see below) to be set to one of two 
definite values. Nitrogen can be made to flow in the gap between the ion 
sweep cone and the spray cone, and to exit the openings of the ion sweep 
cone.

The ion transfer capillary is an elongated cylindrical stainless steel tube that 
is attached to the spray cone. The ion transfer capillary assists in desolvating 
ions that are produced by the ESI, APCI, or NSI probes. Ions are focused into 
the ion transfer capillary in the atmospheric pressure region and transported to 
the skimmer region of the vacuum manifold by a decreasing pressure gradient 
and electrostatic forces. The ion transfer capillary can be heated to 300 ºC. 
Typical temperatures of the ion transfer capillary are 200 °C for ESI, 150 °C 
for APCI, and 165 °C for NSI.

The heater assembly is a dual cartridge heater that surrounds the ion transfer 
capillary but is not connected to the ion transfer capillary. The ion transfer 
capillary passes through a vent prevent ball valve that automatically seals if 
the ion transfer capillary is removed. Therefore, the ion transfer capillary may 
be removed and replaced without venting the instrument.

The extension mount is a combined tube and flange like part that mounts to 
the spray shield. The extension mount surrounds the ion transfer capillary and 
is a mount for the tube lens and skimmer mount. 

Содержание LCQ Deca XP Plus

Страница 1: ...LCQ Deca XP Plus Hardware Manual Revision A 97344 97003 TM ...

Страница 2: ...ita City Osaka 564 0063 81 06 6387 6681 Netherlands Thermo Finnigan BV Druivenstraat 33 NL 4816 KB Breda 31 076 587 8722 P R China Thermo Finnigan China Room 912 916 Ping an Mansion No 23 Jin Rong Street Xi Cheng District Beijing 100032 86 010 6621 0839 Spain ThermoQuest SA Avenida de Valdelaparra 27 Edificio Alcor Planta 2a ES 28108 Alcobendas Madrid 34 091 657 4930 Spain ThermoQuest SA Acer 30 3...

Страница 3: ...ditional comments please do Attach additional sheets if necessary ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ Please tear this sheet from the manual fold it closed s...

Страница 4: ...fold From EDITOR TECHNICAL PUBLICATIONS THERMO FINNIGAN LC AND LC MS DIVISION 355 RIVER OAKS PARKWAY SAN JOSE CA 95134 1991 UNITED STATES OF AMERICA Place Stamp Here fold ...

Страница 5: ...ement parts should be ordered from Thermo Finnigan or one of its authorized representatives FCC Compliance Statement Note This equipment has been tested and found to comply with the limits for a Class A digital device pursuant to part 15 of the FCC rules These limits are designed to provide reasonable pro tection against harmful interference when the equipment is operated in a commercial environ m...

Страница 6: ...rt for lifting and or moving the instrument This instrument is too heavy and or bulky for one person alone to handle safely Notice on the Proper Use of Thermo Finnigan LC and LC MS Division Instruments In compliance with international regulations If this instrument is used in a manner not speci fied by Thermo Finnigan the protection provided by the instrument could be impaired 97033 97133 97044 97...

Страница 7: ... xii Topic Headings xiii Safety Precautions xiv Solvent and Gas Purity Requirements xvi Service Philosophy xvii Level of Repair xvii Reply Cards xviii Functional Description 1 1 1 1 API Source 1 2 API Probe Related Components 1 2 API Stack 1 14 1 2 Ion Optics 1 17 1 3 Mass Analyzer 1 19 1 4 Ion Detection System 1 20 Changing API Probe Assemblies 2 1 2 1 Removing the APCI Probe Assembly 2 2 2 2 Ins...

Страница 8: ...tector 3 6 Setting Up Conditions for Operation 3 7 3 5 Resetting the MS Detector 3 8 3 6 Resetting the Tune and Calibration Parameters to their Default Values 3 9 3 7 Turning Off Selected MS Detector Components 3 10 User Maintenance 4 1 4 1 Tools and Supplies 4 3 4 2 Frequency of Cleaning 4 5 4 3 API Source Maintenance 4 6 Flushing the Sample Transfer Line Sample Tube and API Probe 4 6 Flushing th...

Страница 9: ...fold 5 15 Reinstalling the Top Cover of the MS Detector 5 16 Starting Up the System 5 16 Tuning the Ring Electrode and Quadrupole Octapole RF Voltages 5 16 5 4 Replacing the Electron Multiplier 5 23 5 5 Diagnostics 5 28 5 6 Replacing a Fuse 5 31 5 7 Replacing PCBs and Assemblies 5 36 5 8 Replacing PCBs and Assemblies in the Tower 5 37 Replacing PCBs in the Embedded Computer 5 42 Replacing the Vent...

Страница 10: ...em Electron Multiplier Conversion Dynode 6 7 Top Cover Plate of Vacuum Manifold 6 8 Divert Inject Valve 6 8 Syringe Pump 6 8 Turbomolecular Pump 6 9 Rotary Vane Pumps 6 9 Vacuum System Assemblies 6 9 Mechanical Assemblies 6 10 Electrical Assemblies 6 10 Printed Circuit Boards PCBs 6 11 RF Control Detection Assemblies 6 11 Cables 6 12 Covers 6 13 6 2 Data System Hardware 6 14 6 3 Chemicals Kit 6 15...

Страница 11: ...tor Chapter 2 Changing ESI or APCI Probe Assemblies contains procedures for changing ESI and APCI probes Chapter 3 System Shutdown Startup and Reset provides procedures for shutting down and starting up the LCQ Deca XP Plus system Chapter 4 User Maintenance outlines the maintenance procedures that you should perform on a regular basis to maintain optimum MS detector performance Chapter 5 Service M...

Страница 12: ...re Manual ________________ Changes to the Manual and Online Help To suggest changes to this manual or the online Help please send your comments to Editor Technical Publications Thermo Finnigan LC and LC MS Division 355 River Oaks Parkway San Jose CA 95134 1991 U S A You are encouraged to report errors or omissions in the text or index Thank you ...

Страница 13: ...eric pressure ionization ASCII American Standard Code for Information Interchange b bit B byte 8 b baud rate data transmission speed in events per second C degrees Celsius CD compact disc CD ROM compact disc read only memory cfm cubic feet per minute CI chemical ionization CIP carriage and insurance paid to cm centimeter cm3 cubic centimeter CPU central processing unit of a computer CRM consecutiv...

Страница 14: ...free on board ft foot FTP file transfer protocol g gram G giga 109 GC gas chromatograph gas chromatography GC MS gas chromatograph mass spectrometer GND electrical ground GPIB general purpose interface bus GUI graphical user interface h hour h height HPLC high performance liquid chromatograph HV high voltage Hz hertz cycles per second ICIS Interactive Chemical Information System ICL Instrument Con...

Страница 15: ...r m milli 10 3 M mega 106 M molecular ion MH protonated molecular ion min minute mL milliliter mm millimeter MS mass spectrometer mass spectrometry MS MSn power where n 1 MS MS MSn power where n 2 MSn MSn power where n 1 through 10 m z mass to charge ratio n nano 10 9 NCBI National Center for Biotechnology Information USA NIST National Institute of Standards and Technology USA Ω ohm OD outside dia...

Страница 16: ...e SRM selected reaction monitoring SSQ single stage quadrupole TCP IP transmission control protocol Internet protocol TIC total ion current Torr torr TSQ triple stage quadrupole u atomic mass unit URL uniform resource locator V volt V ac volts alternating current V dc volts direct current vol volume w width W watt WWW World Wide Web Note Exponents are written as superscripts In the corresponding o...

Страница 17: ...ted in this manual by capitalizing the initial letter of each word and italicizing each word Input that is to be entered by keyboard or buttons that are to be clicked on by the mouse is represented in bold face letters Titles of topics chapters and manuals also appear in bold face letters For brevity expressions such as choose File Directories are used rather than pull down the File menu and choos...

Страница 18: ...ins information that can affect the quality of your data In addition notes often contain information that you may need if you are having trouble A Caution contains information necessary to protect your instrument from damage A CAUTION describes hazards to human beings Each CAUTION is accompanied by a CAUTION symbol Each hardware manual has a blue CAUTION sheet that lists the CAUTION symbols and th...

Страница 19: ...entions __________________ LCQ Deca XP Plus Hardware Manual ___________________ xiii Topic Headings The following headings are used to show the organization of topics within a chapter Chapter 1 Chapter Name 1 2 Second Level Topics Third Level Topics Fourth Level Topics Fifth Level Topics ...

Страница 20: ...zer may be very hot and may cause severe burns if they are touched Allow heated components to cool before you service them Place the MS Detector in Standby or Off Before You Open the Atmospheric Pressure Ionization API Source The presence of atmospheric oxygen in the API source when the MS detector is On could be unsafe LCQ Deca XP Plus automatically turns the MS detector Off when you open the API...

Страница 21: ...te container can be something as simple as an old solvent bottle with a modified cap Use Care When Changing Vacuum Pump Oil Treat drained vacuum pump oil and pump oil reservoirs with care Hazardous compounds introduced into the system might have become dissolved in the pump oil Always use approved containers and procedures for disposing of waste oil Whenever a pump that has been operating on a sys...

Страница 22: ...ls and is not recommended The following is a list of international sources that can supply high quality solvents The LCQ Deca XP Plus MS detector uses helium as a damping gas The helium should be ultra high purity 99 999 with less than 1 0 ppm each of water oxygen and total hydrocarbons The required gas pressure is 40 psi 10 36 to 44 psi Thermo Finnigan has found that particulate filters are often...

Страница 23: ...stem maximize the up time of your system and allow you to achieve optimum system performance Service not described in this manual should be performed only by a Thermo Finnigan Customer Support Engineer or similarly trained and qualified technical personnel Level of Repair Thermo Finnigan s service philosophy for the LCQ Deca XP Plus system calls for troubleshooting to the lowest part assembly PCB ...

Страница 24: ...rn the card you are placed on the Thermo Finnigan mailing list Thus you will receive Thermo Finnigan application reports and technical reports in your area of interest and you will be notified of events of interest such as user meetings Second it allows you to tell the Thermo Finnigan LC and LC MS Division what you like and do not like about the manual A message on the Change of Location card asks...

Страница 25: ...___________ LCQ Deca XP Plus Hardware Manual __________________ 1 1 Chapter 1 Functional Description The following topics are discussed in this chapter API source Ion optics Mass analyzer Ion detection system ...

Страница 26: ...chniques You can do this without venting the LCQ Deca XP Plus The three types of API probe related components are ESI probe assembly APCI probe assembly NSI source assembly ESI Probe Assembly The ESI probe assembly consists of the ESI flange the ESI slide assembly and the ESI probe See Figure 1 1 Figure 1 2 and Figure 1 3 The ESI flange holds the ESI slide assembly The ESI slide assembly holds the...

Страница 27: ...re the ESI probe to the slide of the ESI slide assembly and prevent movement of the probe orthogonal to the axis of the ion transfer capillary Even when the probe retainer bolt is in use for this purpose the probe can be moved parallel to the axis of the ion transfer capillary Figure 1 1 ESI probe assembly showing AUX gas connected Flange Retainer Bolt Probe Retainer Bolt Auxiliary Gas Line Fittin...

Страница 28: ... sheath gas plumbing delivers dry nitrogen gas to nozzle The auxiliary gas plumbing also delivers dry nitrogen to the nozzle The sheath gas is the inner coaxial nitrogen gas that sprays nebulizes the sample solution into a fine mist as it exits the sample tube Typical sheath gas flow rates for ESI are 60 units for sample flow rates of 3 µL min and 80 units for sample flow rates of 1 mL min Typical...

Страница 29: ...________ 1 5 Figure 1 2 Cross sectional view of the ESI probe assembly SAMPLE TUBE AND PEEK SAFETY SLEEVE GROUNDED FITTING ESI FLANGE ESI MANIFOLD SAMPLE INLET SHEATH GAS INLET AXIAL ADJUSTING THUMB SCREW SPRAY CHAMBER WALL ATMOSPHERIC PRESSURE REGION ESI NEEDLE ESI NOZZLE AUXILIARY GAS INLET ESI PROBE ...

Страница 30: ...__________LCQ Deca XP Plus Hardware Manual ________________ Figure 1 3 Geometry of the ESI probe and API stack Ion Transfer Capillary Heater To Ion Skimmer Pressure 1 Torr 10 V Atmospheric Pressure Region Ion Sweep Cone Charged Droplet Solvent Evaporates From Droplet Ejected Positive Ions ESI Needle 5 kV ESI Nozzle ...

Страница 31: ...150 to 225 C Required Typical setting 5 to 25 units Not required but might help depending on conditions LC at flow rates from 200 to 500 µL min 2 to 3 mm ID C 5 Typical setting 220 to 350 C Required Typical setting 35 to 65 units Not required but usually helps to reduce solvent background ions Typical setting 20 units LC at flow rates from 0 5 probe position 3 to 1 mL min probe position 4 4 6 mm I...

Страница 32: ...capillary A probe retainer bolt can be used to secure the APCI probe to the slide of the APCI slide assembly and prevent movement of the probe orthogonal to the axis of the ion transfer capillary Even when the probe retainer bolt is in use for this purpose the probe can be moved parallel to the axis of the ion transfer capillary The APCI probe accommodates liquid flows of 100 µL min to 2 mL min an...

Страница 33: ...s The corona discharge needle assembly is mounted on the APCI flange The assembly positions the tip of the corona discharge needle near the vaporizer A small screw can be used to adjust manually the position of the needle into or out of the assembly A high potential typically 3 to 5 kV is applied to the corona discharge needle to produce a corona discharge current of up to 10 µA A typical value of...

Страница 34: ...rdware Manual ________________ Figure 1 4 APCI probe assembly showing AUX gas connected Flange Retainer Bolt Vaporizer Heater Cable Probe Retainer Bolt Auxiliary Gas Line Fitting Green Sample Transfer Line Fitting Red Probe Guide Corona Needle High Voltage Connector Fastener Underside Probe Position Adjustment Bolt Sheath Gas Line Fitting Blue ...

Страница 35: ...view of the APCI probe assembly Corona Discharge Needle Assembly APCI Probe APCI Flange Corona Discharge Power Connector Vaporizer Power Connector Axial Adjusting Thumbscrew APCI Nozzle Adjustment Handle Vaporizer Vaporizer Tube Vaporizer Heater Retainer Corona Discharge Needle APCI Manifold Auxiliary Gas Inlet Sheath Gas Inlet Sample Inlet ...

Страница 36: ... APCI probe and the API stack ION TRANSFER CAPILLARY PRESSURE 1 TORR 10 V CORONA DISCHARGE NEEDLE 3 TO 5 kV VAPORIZER TUBE 500 C ATMOSPHERIC PRESSURE REGION ION SWEEP CONE SHEATH GAS TUBE OUTER AUXILIARY GAS SAMPLE TUBE INNER S S S S S S S S S M M M H H O 3 e e N 2 N 2 N e 2 N e 2 H O 2 M M M M M CORONA DISCHARGE NEEDLE 3 TO 5 kV CORONA DISCHARGE REGION PLASMA H20 H20 H20 CHEMICAL IONIZATION H20 H...

Страница 37: ...e static probe and the dynamic or flow probe The static NSI probe typically uses a glass or quartz tip pulled to form an orifice with 5 to 30 µm ID The tip is coated with gold palladium in the vicinity of the orifice and voltage is applied to the tip by means of a metal spring clip To use static NSI sample solution is pipetted into the spray tip Gas pressure is used to start and maintain the spray...

Страница 38: ... shield The ion sweep cone is usually placed in one of two positions on the spray cone This allows the distance between the opening of the ion sweep cone and the opening of the ion transfer capillary see below to be set to one of two definite values Nitrogen can be made to flow in the gap between the ion sweep cone and the spray cone and to exit the openings of the ion sweep cone The ion transfer ...

Страница 39: ...re Manual _____________________________________ 1 15 Figure 1 7 Cross sectional view of the API stack ION TRANSFER CAPILLARY EXTENSION MOUNT TUBE LENS SKIMMER TUBE LENS AND SKIMMER MOUNT DRAIN SPRAY SHIELD SPRAY CONE ION SWEEP CONE VENT PREVENT BALL HEATER BLOCK ...

Страница 40: ... analyzer A potential of 200 V is used to deflect positive ions away from the opening in the skimmer and a potential of 200 V is used to deflect negative ions away from the opening in the skimmer Ions from the tube lens pass through the skimmer and move toward the first octapole The skimmer acts as a vacuum baffle between the higher pressure skimmer region at 1 Torr and the lower pressure first oc...

Страница 41: ...0 to 10 V that are applied to the rods give rise to an electric field that guides the ions along the axis of the quadrupole During ion transmission the offset voltage is negative for positive ions and positive for negative ions The octapole is an octagonal array of cylindrical rods that acts as an ion transmission device An RF voltage 2 45 MHz 400 V peak to peak and dc offset voltage typically 10 ...

Страница 42: ...o serves as a baffle between the quadrupole region and the analyzer region of the vacuum manifold The XP Plus tune procedure optimizes the potentials that are applied to the quadrupole octapole and interoctapole lens to maximize the ion current to the mass analyzer During ion transmission a potential of typically between 20 and 20 V is applied to the interoctapole lens The potential is negative fo...

Страница 43: ...ers to permit the passage of ions into and out of the mass analyzer cavity The ring electrode is located between the endcap electrodes Ions produced in the API source enter the mass analyzer cavity through the entrance endcap electrode Ions can be ejected through either endcap electrode during mass analysis Ions that are ejected through the exit endcap electrode are focused by the conversion dynod...

Страница 44: ... electrons When negative ions strike a positively charged conversion dynode the secondary particles of interest are positive ions These secondary particles are focused by the curved surface of the conversion dynode and are accelerated by a voltage gradient into the electron multiplier The conversion dynode shield tube and disk shield the vacuum manifold from the electric field produced by the conv...

Страница 45: ... by the anode is proportional to the number of secondary particles striking the cathode Typically the electron multiplier is set to a gain of about 3 105 i e for each ion or electron that enters 3 105 electrons exit The current that leaves the electron multiplier via the anode is converted to a voltage by the electrometer circuit and is recorded by the data system The ion detection system of the X...

Страница 46: ......

Страница 47: ...rately in the LCQ Series Nanospray Ion Source Operator s Manual The ESI probe assembly consists of the ESI flange and probe The APCI probe assembly consists of the APCI flange probe and corona discharge needle assembly You do not need to shut down or vent the system to change the API probe assembly The topics in this chapter are as follows Removing the APCI probe assembly Installing the ESI probe ...

Страница 48: ...cure the APCI probe assembly to the API spray shield See Figure 2 1 5 Pull the APCI probe assembly still attached to the probe guide back from the spray shield 6 Disconnect the corona needle high voltage cable from the corona needle high voltage connector To disconnect the cable rotate the locking ring on the cable counterclockwise until you can pull the cable free 7 Disconnect the vaporizer heate...

Страница 49: ...he APCI probe by turning the auxiliary gas line fitting green counterclockwise until you can pull the auxiliary gas line and fitting free 11 With one hand holding the APCI flange loosen the knurled fastener under the probe guide that secures the APCI flange to the probe guide adapter 12 Remove the APCI probe assembly from the probe guide adapter by sliding it towards the spray shield and off the p...

Страница 50: ...s Hardware Manual ________________ Figure 2 1 APCI probe assembly showing AUX gas connected Flange Retainer Bolt Vaporizer Heater Cable Probe Retainer Bolt Auxiliary Gas Line Fitting Green Sample Transfer Line Fitting Red Probe Guide Corona Needle High Voltage Connector Fastener Underside Probe Position Adjustment Bolt Sheath Gas Line Fitting Blue ...

Страница 51: ...away from the spray shield and onto the probe guide adapter Secure the ESI flange to the probe guide adapter with the knurled fastener that is located on the underside of the probe guide adapter 4 With one hand hold the ESI probe on the nozzle side of the probe With the other hand connect the high voltage power cable to the connector on the ESI probe Turn the locking ring on the cable clockwise to...

Страница 52: ...ethods directory for a variety of applications including ESI high flow and ESI low flow LC MS experiments In the Tune Plus window choose File Open to display the tune files Refer to LCQ Deca XP Plus Getting Started for instructions on tuning and operating the XP Plus in the ESI mode Flange Retainer Bolt Probe Retainer Bolt Auxiliary Gas Line Fitting Green Probe Slide Adapter Probe Position Adjustm...

Страница 53: ...rounded transfer line fitting on the ESI flange See Figure 2 2 The sample transfer line is the line that comes from the LC divert injector valve or syringe pump It is not the fused silica capillary that enters the ESI probe 5 Disconnect the sheath gas line and fitting from the inlet labeled Sheath Gas on the ESI probe by turning the sheath gas line fitting blue counterclockwise until you can pull ...

Страница 54: ...e topic Maintaining the APCI Probe in the User Maintenance chapter Ensure that the probe retainer bolt is tight and the APCI probe is secured to the slide which is attached to the APCI flange 5 Pull the probe guide adapter away from the spray shield Starting with the APCI flange on the spray shield side of the probe guide adapter slide the APCI flange away from the spray shield and onto the probe ...

Страница 55: ...gned with the white line on the connector 11 Push the APCI probe assembly against the spray shield 12 Secure the APCI flange to the spray shield with the two flange retainer bolts 13 Place the electronics service switch in the Operational position 14 In the Tune Plus window choose Setup Change to APCI to configure the XP Plus for APCI operation Note The XP Plus data system contains customized tune...

Страница 56: ......

Страница 57: ...e XP Plus can be placed in Standby condition if the system is not to be used for 12 h or more The following topics are discussed in this chapter Shutting down the system in an emergency Placing the system in Standby condition Shutting down the system completely Starting up the system after a complete shutdown Reseting the MS detector Reseting the tune and calibration parameters to their default va...

Страница 58: ...ee Figure 3 1 This turns off all power to the MS detector including the vacuum pumps Although removing power abruptly will not harm any component within the system this is not the recommended shutdown procedure to follow Refer to the topic Shutting Down the System Completely for the recommended procedure To turn off the LC autosampler and computer in an emergency use the On Off switches on the LC ...

Страница 59: ...version dynode 8 kV power to the API source ring electrode RF voltage and octapole RF voltage The XP Plus also turns off the auxiliary gas and sets the sheath gas flow to 0 units See Table 3 1 on page 3 10 for the On Off status of MS detector components when the MS detector is in the Standby condition The System LED on the front panel of the MS detector is illuminated yellow when the system is in ...

Страница 60: ...the power panel see Figure 3 1 on page 3 2 in the Service Position Power to the non vacuum system electronics is turned off when you place the electronics service switch in the Service Position 4 Place the main power circuit breaker switch located on the power panel see Figure 3 1 in the Off O position When you place the main power circuit breaker switch in the Off O position the following occurs ...

Страница 61: ...___________ 3 5 Note If you are planning to perform routine or preventive system maintenance on the MS detector only you do not need to turn off the LC autosampler and data system In this case the shutdown procedure is completed However if you do not plan to operate your system for an extended period of time we recommend that you turn off the LC autosampler and data system ...

Страница 62: ... place the main power circuit breaker switch in the On position the rotary vane pump and the turbomolecular pump are started All LEDs on the MS detector front panel are off 4 Place the electronics service switch in the Operating Position When you place the electronics service switch in the Operating Position the following occurs The Power LED on the MS detector front panel is illuminated green to ...

Страница 63: ...e vacuum manifold can cause reduced sensitivity tuning problems and a reduced lifetime of the electron multiplier 2 Ensure that the helium pressure and nitrogen pressure are within the operational limits helium 40 10 psig 275 70 kPa nitrogen 100 20 psig 690 140 kPa 3 Select the Status View button in the Tune Plus window Check to see if the pressure measured by the ion gauge is below about 5 10 5 T...

Страница 64: ...location of the Reset button When you press the Reset button the following occurs An interrupt on the CPU PCB of the embedded computer causes the embedded computer to reboot All LEDs on the front panel of the MS detector are off except the Power LED After several seconds the Communication LED is illuminated yellow to indicate that the data system and the MS detector are starting to establish a com...

Страница 65: ... set some parameters that have resulted in less than optimum performance To reset the XP Plus tune and calibration parameters to their default values proceed as follows In the Tune Plus window choose File Restore Factory Calibration to restore the default calibration parameters or choose File Restore Factory Tune Method to restore the default tune parameters Note Make sure that the problems that y...

Страница 66: ...s similar to Standby condition except all high voltage components of the MS detector are turned off Choose Control Off from the Tune Plus window to place the MS detector in the Off condition Place the electronics service switch in the Service Position The electronics service switch allows you to perform maintenance procedures involving non vacuum system components of the MS detector Place the main...

Страница 67: ... Off Off Off APCI vaporizer Off Off Off Off ESI needle Off Off Off Off Sheath gas Off Off Off Off Auxiliary gas Off Off Off Off Helium damping gas On On On On Vent valve Closed Closed Closed Open after 30 s Turbomolecular pump On On On Off Rotary vane pump On On On Off Vent Delay PCB On On On Off after 30 s Embedded computer On On Off Off Turbomolecular Pump Controller On On On Off Power supply el...

Страница 68: ...n On On Off Power supply 180 V dc On On Off Off Power supply 150 V dc On Off Off Off Power supply 36 V dc On Off Off Off Power supply 20 V dc On On Off Off Power supply 205 V dc On Off Off Off Power supply 48 24 V dc On On On Off Power supply 4 V ac On On Off Off Fan turbomolecular pump On On On Off Fan RF coil On On Off Off Fans tower On On Off Off Fan embedded computer On On Off Off Table 3 1 On...

Страница 69: ...uit breaker is on The syringe pump goes from On to Off only when the system goes from scan mode to Standby condition Convectron gauge On On Off Off Ion gauge On On Off Off Syringe pump On On Off Off Table 3 1 On Off status of MS detector components voltages and gas flows continued MS Detector Component Standby Off Electronics Service Switch in Service Position Main Power Circuit Breaker Switch in ...

Страница 70: ......

Страница 71: ... procedures MS Detector Component Procedure Frequency Procedure Location API source Flush clean sample transfer line sample tube and API probe Daily Page 4 6 API source Flush clean ion transfer capillary Daily or as needed Page 4 8 API source Flush clean spray shield spray cone Daily Page 4 8 Rotary vane pump Purge decontaminate oil Weekly or as needed Chapter 5 API source Clear ion transfer capil...

Страница 72: ...ce Note The keys to success with the procedures in this chapter are Proceed methodically Always wear clean lint free gloves when handling the components of the API source ion optics mass analyzer and ion detection system Always place the components on a clean lint free surface Always cover the opening in the top of the vacuum manifold with a large lint free tissue whenever you remove the top cover...

Страница 73: ...ls equipment and chemicals Description Part Number Wrench 5 16 in hex socket Allen Wrench 9 16 in socket Wrench 7 16 in open end Wrench 9 16 in open end Wrench 5 16 in open end Wrench 1 2 in open end Wrench 3 8 in open end Screwdrivers set ball point Allen also referred to as ball drivers 00025 03025 Screwdriver slot head large Screwdriver slot head small Screwdriver Phillips small Fused silica cu...

Страница 74: ...________________ 4 4 ____________________LCQ Deca XP Plus Hardware Manual ________________ CAUTION As with all chemicals solvents and reagents should be stored and handled according to standard safety procedures and should be disposed of according to local and federal regulations ...

Страница 75: ...s Flushing the Sample Transfer Line Sample Tube and API Probe and Flushing the Spray Shield Ion Sweep Cone Spray Cone and Ion Transfer Capillary on page 4 6 and page 4 8 respectively The tube lens and skimmer of the API source become dirty at a slower rate than the API probe spray shield and ion transfer capillary Refer to the topic Maintaining the API Stack on page 4 27 The ion optics and the mas...

Страница 76: ...APCI sample tube Maintain the ESI probe assembly including replacing the ESI sample tube Maintain the API stack including replacing the ion transfer capillary Flushing the Sample Transfer Line Sample Tube and API Probe You should flush the sample transfer line sample tube and API probe at the end of each working day or more often if you suspect they are contaminated by flowing a 50 50 methanol dis...

Страница 77: ...r click on the APCI Source button The APCI Source dialog box appears c In the APCI Source dialog box use the Vaporizer Temp spin box to set the vaporizer temperature to 500 C d Use the Sheath Gas Flow Rate spin box to set the sheath gas flow rate to 80 units e Use the Aux Flow Rate spin box to set the auxiliary gas flow rate to 10 units f Use the LVFKDUJH XUUHQW VSLQ ER WR VHW WKH GLVFKDUJH FXUUHQ...

Страница 78: ...ialog box appears b Select the LC tab c Click on Stop to stop the LC pump 8 After 5 min turn off the API source by placing the MS detector in Standby as follows From the Tune Plus window choose Control Standby or click on the On Standby button to put the MS detector in Standby Go on to the next topic Flushing the Spray Shield Ion Sweep Cone Spray Cone and Ion Transfer Capillary Flushing the Spray ...

Страница 79: ...sfer capillary heater off 3 Loosen the two flange retainer bolts that secure the API flange APCI or ESI flange to the spray shield 4 Pull back the API flange from the spray shield 5 Pull the ion sweep cone off of the spray cone and place it on a large Kimwipe or other lint free tissue Temporarily place another large Kimwipe on the bottom of the spray shield This Kimwipe is required to absorb the s...

Страница 80: ...replaced without loss of vacuum and you might want to replace the ion transfer capillary instead of cleaning the ion transfer capillary If the pressure in the API region as measured by the Convectron gauge drops considerably below 1 Torr you should suspect a blocked ion transfer capillary You can check the Convectron gauge pressure in the Vacuum dialog box by choosing Setup Vacuum from the Tune Pl...

Страница 81: ...retainer bolts Maintaining the APCI Probe The APCI probe requires a minimum of maintenance The APCI sample tube 150 µm ID fused silica tubing is preloaded at the factory However if the sample tube becomes obstructed with salt precipitates or is broken you need to replace it Also you may need to disassemble the APCI probe for cleaning or to replace a part CAUTION The APCI vaporizer typically operat...

Страница 82: ...ple tube Installing the APCI sample tube Reassembling the APCI probe assembly Reinstalling the APCI probe assembly Note You should flush the APCI probe at the end of each working day by flowing a 50 50 methanol water solution from the LC through the APCI source Refer to the topic Flushing the Sample Transfer Line Sample Tube and API Probe on page 4 6 Note Wear clean gloves when you handle APCI pro...

Страница 83: ...safe place 2 Remove the APCI probe from the APCI flange as follows a Unbolt the APCI slider assembly from the APCI flange You will not be able to remove the probe from the flange at this time because the cable from the APCI vaporizer heater is still connected to the flange CAUTION AVOID BURNS The APCI vaporizer heater can reach temperatures of 600 C Always allow the APCI probe to cool to ambient t...

Страница 84: ...a With an Allen wrench remove the socket head screw that secures the heater retainer to the vaporizer casing b Remove the heater coil and quartz insulator from the vaporizer 3 Complete the disassembly of the APCI probe as follows See Figure 4 1 on page 4 12 for the location of the components a Unscrew and remove the vaporizer casing from the APCI manifold b Remove the probe collar P N 97144 20024 ...

Страница 85: ...Removing the APCI Sample Tube 11 Reinstall the APCI nozzle P N 70005 20196 by gently screwing it by hand into the APCI manifold 12 Reinstall the APCI collar P N 97144 20024 13 Reinstall the vaporizer casing P N 70005 20217 by gently screwing it by hand into the APCI manifold Removing the APCI Sample Tube To remove the APCI sample tube from the APCI manifold do the following 1 With a 3 8 in open en...

Страница 86: ...ce it if necessary 4 Insert the fused silica tubing into the sample tube inlet fitting 5 Slide the exit end nut and ferrule down the fused silica tubing and into the sample tube inlet fitting 6 Tighten the exit end nut to secure the new sample tube fused silica tubing 7 Remove the probe collar from the APCI manifold 8 Unscrew and remove the vaporizer casing from the APCI manifold to expose the noz...

Страница 87: ...e to the APCI manifold The green ground wire has deliberately been made longer than absolutely necessary and you should coil the wire to obtain proper fit Make sure that the flat side of the connector is against the APCI manifold 5 Reinstall the heater retainer and secure it with the socket head screw Figure 4 3 Proper position of the exit end of the APCI sample tube Note Once the APCI sample tube...

Страница 88: ... APCI Probe Assembly To reinstall the APCI probe assembly onto the XP Plus follow the procedure described in the topic Installing the APCI Probe Assembly in the Changing API Probe Assemblies chapter or place the APCI probe assembly in its storage container Maintaining the ESI Probe The ESI probe requires a minimum of maintenance If the fused silica sample tube is plugged or broken you need to repl...

Страница 89: ... the sample tube with PEEK safety sleeve and the Kel F sample inlet fitting adapter from the ESI probe as follows a Unscrew the 10 32 1 4 28 Kel F fitting adapter P N 00101 18080 with the red fingertight fitting attached b Remove the Kel F fitting adapter and the sample tube with PEEK safety sleeve by pulling them out from the ESI probe 3 Loosen the probe retainer bolt that holds the ESI probe in ...

Страница 90: ...____________ Figure 4 4 Cross sectional view of the ESI probe assembly Sample Tube And PEEK Safety Sleeve Grounded Fitting ESI Flange ESI Manifold Sample Inlet Sheath Gas Inlet Axial Adjusting Thumb Screw Spray Chamber Wall Atmospheric Pressure Region ESI Needle ESI Nozzle Auxiliary Gas Inlet ESI Probe ...

Страница 91: ...for the ESI voltage may not be able to reach the level you set it to This problem is a result of the formation of current leakage paths on the ESI probe The two zones where leakage paths can occur are the following Between the high voltage nozzle and the grounded ESI flange In the high voltage connector within the ESI probe In the first case disassembly of the probe is not necessary To remove this...

Страница 92: ...4 22 _____________________________________ LCQ Deca XP Hardware Manual ___________________________________________ Figure 4 5 Exploded view of the ESI probe ...

Страница 93: ...seal extractor tool P N 70005 20304 provided in the Accessories Kit or another appropriate tool to get the spring out Place these parts on a clean surface 6 Rinse the ESI manifold with distilled water and then with HPLC grade methanol Use a Kimwipe to remove excess methanol from the ESI manifold 7 Dry the ESI manifold with nitrogen gas 8 Inspect all of the O rings and replace any that are damaged ...

Страница 94: ...ifold c Install the spiral wave spring into the ESI manifold d Thread the ESI nozzle over the needle and into the ESI manifold Slightly wet the nozzle threads with HPLC grade methanol for lubrication e With a 5 16 in wrench gently tighten the ESI nozzle until it is a little more than finger tight Do not overtighten CAUTION AVOID ELECTRICAL SHOCK When you are operation your instrument in the ESI mo...

Страница 95: ...Sample d Slide the 10 32 1 4 28 Kel F fitting adapter P N 00101 18080 over the sample tube and tighten the fitting onto the ESI probe sample inlet e Slide the precut 25 cm 10 in 0 009 in ID 0 0240 in OD PEEK safety sleeve P N 00301 22806 over the sample tube f Slide the 0 027 in ID PEEK ferrule P N 00101 18119 narrow end first over the PEEK safety sleeve and to the 10 32 1 4 28 Kel F fitting adapt...

Страница 96: ...sleeve otherwise the sample stream might enter between the sample tube and the PEEK safety sleeve Ensure the sample tube is held tightly in the grounded fitting by gently pulling the sample tube from the exit end of the ESI needle n Use a fused silica cutting tool to cut the sample tube at the ESI needle so that only 2 5 cm 1 in remains protruding from the exit end of ESI needle o From the ESI sam...

Страница 97: ...er Maintaining the API Stack The API stack includes the spray shield ion sweep cone spray cone ion transfer capillary capillary lens and skimmer mount and the tube lens and skimmer The ion transfer capillary has a finite lifetime You need to replace the ion transfer capillary if the ion transfer capillary bore becomes corroded or damaged You also need to clean the spray shield ion sweep cone spray...

Страница 98: ...ecure the API flange APCI or ESI to the spray shield 4 Pull back and remove the API probe flange from the spray shield 5 Remove the ion sweep cone from the spray cone 6 Using the ion transfer capillary tool P N 70111 20258 unscrew the ion transfer capillary from the spray cone 7 Using the ion transfer capillary tool hook the ion transfer capillary and remove it Replace the Kalrez O ring P N 00107 ...

Страница 99: ...o on to the next topic Removing the API Stack Removing the API Stack To remove the API stack proceed as follows 1 Loosen the two flange retainer bolts that secure the API probe assembly to the spray shield 2 Pull back the API probe assembly from the spray shield 3 Disconnect the waste line from the spray shield 4 Disconnect the API stack electrical cable from the spray shield by turning the tab on...

Страница 100: ...clean surface with the spray shield down Allow the API stack to cool to ambient temperature before you disassemble the API stack The API stack is shown in Figure 4 8 Go on to the next topic Disassembling the API Stack Note If you are unable to dislodge the spray shield from the vacuum manifold reattach the API flange to the spray shield and then pull the flange away from the vacuum manifold Figure...

Страница 101: ...electrical lead from the lead pin on the tube lens 6 Push the tube lens and skimmer mount into the extension mount and remove the retaining clip Allow the tube lens and skimmer mount to move back slowly 7 Detach the skimmer from the tube lens and skimmer mount by pushing on its lead pin 8 Detach the tube lens from the tube lens and skimmer mount by pushing the tube lens away from the mount 9 Pull ...

Страница 102: ...Hardware Manual ___________________________________________ Figure 4 9 Exploded view of the back of the API stack Graphite Seal Heater Thumb Nuts 2 Retainer Clip Wave Spring Tube Lens Skimmer Lead Pin Spray Shield Tube Lens And Skimmer Mount Extension Mount ...

Страница 103: ...able without venting the XP Plus however if you wish to clean the ion transfer capillary do the following 1 Use methanol and a Kimwipe to clean the entrance end exit end and exterior of the ion transfer capillary 2 Clear the bore of the ion transfer capillary by inserting and withdrawing the 28 gauge 10 in hypodermic tube P N 00106 20000 included in your accessory kit CAUTION The APCI vaporizer ty...

Страница 104: ...s follows Refer to Figure 4 8 and Figure 4 9 for the location of the API stack components 1 It is recommended that you replace the graphite seal P N 7011 20216 2 Seat the heater in the spray shield and secure with the two thumb nuts 3 Reconnect the heater cable to the connector that is held by the spray shield Turn the locking ring on the cable clockwise to lock the cable 4 Insert the extension mo...

Страница 105: ...0107 14100 has no cracks is otherwise in good condition and is properly seated on the spray shield Ensure that all components fit together tightly 11 Reinstall the ion transfer capillary See Figure 4 10 Replace the Kalrez O ring P N 00107 12750 if necessary Refer to the topic Maintaining the API Stack on page 4 27 12 Reinstall the ion sweep cone if being used Go on to the next topic Reinstalling t...

Страница 106: ...s aligned with the guide pin hole in the vacuum manifold 2 Carefully insert the API stack into the opening in the vacuum manifold until it seats in the vacuum manifold 3 Reconnect the API stack cable to the connector on the spray shield Turn the tab on the end of the cable clockwise away from you to secure the cable 4 Reconnect the waste line to the spray shield Go on to the next topic Starting Up...

Страница 107: ...lean quadrupole octapole and interoctapole lens As needed Page 5 5 Trap entrance lens Clean trap entrance lens As needed Page 5 5 Mass analyzer Clean mass analyzer Yearly or as needed Page 5 5 Ion detection system Clean ion detection system electron multiplier and conversion dynode Whenever the top cover plate of the vacuum manifold is removed Page 5 15 Ion detection system Replace electron multip...

Страница 108: ...iplier Diagnostics Replacing a fuse Replacing PCBs and Assemblies Note The keys to success with the procedures in this chapter are Proceed methodically Always wear clean lint free gloves when handling the components of the ion optics mass analyzer and ion detection system Always place the components on a clean lint free surface Always cover the opening in the top of the vacuum manifold with a larg...

Страница 109: ...quipment and chemicals Description Part Number Wrench 5 16 in hex socket Allen Wrench 9 16 in socket Wrench 7 16 in open end Wrench 9 16 in open end Wrench 5 16 in open end Wrench 1 2 in open end Wrench 3 8 in open end Screwdrivers set ball point Allen also referred to as ball drivers 00025 03025 Screwdriver slot head large Screwdriver slot head small Screwdriver Phillips small Fused silica cuttin...

Страница 110: ...lower than the API source Refer to the topic Cleaning the Ion Optics and Mass Analyzer Parts on page 5 10 Clean the electron multiplier and conversion dynode whenever you remove the top plate of the vacuum manifold by blowing them with a clean dry gas Refer to the topic Cleaning the Ion Detection System on page 5 15 When the performance of your system decreases significantly because of contaminati...

Страница 111: ...d quantity of the compounds that you analyze Cleaning the ion optics and mass analyzer involves the following steps Shutting down the system Removing the top cover of the MS detector Removing the top cover plate of the vacuum manifold Removing the ion optics and mass analyzer Disassembling the ion optics and mass analyzer Cleaning the ion optics and mass analyzer parts Reassembling the ion optics ...

Страница 112: ... and by the air pressure differential between the vacuum manifold and atmospheric pressure Six cables and one gas line are connected to the top cover plate To remove the top cover plate proceed as follows See Figure 5 1 1 Disconnect at ANAL AUX 1 IN the octapoles cable that comes from the Analyzer Auxiliary PCB 2 Disconnect at ANALYZER the lenses cable that comes from the System Control PCB 3 Disc...

Страница 113: ...he underside of the top cover plate of the vacuum manifold Use the following procedure to remove the ion optics and mass analyzer from the top cover plate See Figure 5 2 for the location of the ion optics and mass analyzer components Figure 5 1 Electrical connections and damping gas line connection to the top cover plate of the vacuum manifold Damping Gas Line Electron Multiplier High Voltage Cabl...

Страница 114: ...INSERT Figure5_2 ps 11 X 17 Z fold Figure 5 2 Mass analyzer and ion optics ...

Страница 115: ...e line free from the nipple See Figure 5 2 8 Hold the mass analyzer with one hand loosen the two thumb screws that hold the analyzer mount to the baffle 9 With one hand holding the mass analyzer and the other hand holding the analyzer mount lift the mass analyzer octapole and analyzer mount out and away from the baffle on the top cover plate Be careful not to touch the electron multiplier with the...

Страница 116: ...e Ion Optics and Mass Analyzer Parts Use the following procedure to remove contamination from the ion optics and mass analyzer parts Clean each part in turn After cleaning place each part on a clean lint free surface 1 With a soft tooth brush or lint free swab scrub the ion optics or mass analyzer part with a solution of detergent and water 2 Rinse the part with tap water to remove the detergent 3...

Страница 117: ...he damping gas nipple Ensure that the electrode is oriented such that the convex surface faces away from the analyzer mount Also the opening in which the pin on the end of the electrical lead inserts should be close to the top cover plate when the analyzer mount is installed on the top cover plate 3 Place a quartz spacer ring into the groove in the entrance endcap electrode 4 Reinstall the ring el...

Страница 118: ...ntation of the exit lens sleeve 11 Insert the exit lens into the exit lens sleeve such that the lead pin on the exit lens points in the same direction as the 8 pin feedthrough when the analyzer mount is installed on the top cover plate Make sure that the exit lens lead pin does not contact the nut on the end of the mass analyzer post Reinstalling the Ion Optics and Mass Analyzer Use the following ...

Страница 119: ...Inspect the ion optics Ensure that all the parts are aligned properly and that they all fit together snugly 10 Reconnect the electrical lead from pin 8 of the 8 pin feedthrough to the entrance lens See Figure 5 3 11 Reconnect the four electrical leads from pins 1 through 4 of the 4 pin feedthrough to the quadrupole 12 Reconnect the electrical lead from pin 2 of the 8 pin feedthrough to the interoc...

Страница 120: ..._ LCQ Deca XP Hardware Manual ___________________________________________ Figure 5 3 Analyzer electrical connections Quadrupole 4 Pin Feedthrough Interoctapole Lens 4 Pin Feedthrough Entrance Lens Endcap Electrodes Exit Lens 8 Pin Feedthrough ...

Страница 121: ...ifold 2 Check the O ring that surrounds the opening for signs of wear and replace it if necessary P N 97000 40015 Make sure that the O ring is seated properly 3 Carefully lift the top cover plate up by its two handles and turn it over Orient the top cover plate such that the electron multiplier is over the conversion dynode Carefully insert the guide posts on the underside of the top cover plate i...

Страница 122: ...he front of the top cover onto the chassis so that the two guide posts located on the front underside of the top cover enter the guide holes located on the top of the chassis 4 Secure the top cover to the chassis with the two latches located on the front of the chassis 5 Close the left and right front doors of the MS detector 6 Reconnect any tubing between the syringe pump and the API source to ac...

Страница 123: ...e Diagnostics dialog box c Select the Graphs tab See Figure 5 4 d Reposition the Diagnostics dialog box so that it does not obscure the Graph view 3 Tune the quadrupole octapole RF voltage as follows a Select Tune Multipole Frequency in the Test Type list box b Select the Once option button in the How Many Times group box c Start the quadrupole octapole RF voltage tune program A frequency function...

Страница 124: ...aintenance Cleaning the Ion Optics and Mass Analyzer _______________________________________ 5 18 ___________________LCQ Deca XP Plus Hardware Manual ________________ Figure 5 4 Diagnostics dialog box Graph page ...

Страница 125: ...group box c Start the ring electrode RF modulation tune program The Graph view should look like Figure 5 6 The standing wave ratio switch line should be at 10 V over the entire range The detected RF voltage should be a straight line that begins at the origin and intersects the standing wave ratio switch line near the highest mass line The RF voltage modulation should be a curved line that begins a...

Страница 126: ...n lines are all flat then there might be a loose connection Make sure that all cables and leads are properly connected and that the spring loaded pin on the RF voltage feedthrough properly contacts the ring electrode Repeat step 4 5 Tune the ring electrode RF voltage frequency as follows a Select Tune RF Frequency in the Test Type text box The Continuously option button in the How Many Times group...

Страница 127: ...within the frequency window If the frequency cursor lies within the frequency window then the ring electrode RF voltage frequency is tuned properly Click on Stop and exit from the diagnostics program If the frequency cursor lies outside the frequency window then you need to manually adjust the ring electrode RF voltage frequency Leave the Graph view displayed Go on to the next step Figure 5 7 Grap...

Страница 128: ...ning stud in place See Figure 5 8 d With a screw driver turn the tuning stud until the frequency cursor lies slightly to the left of the center of the frequency window The cursor should shift slightly to the right when the air deflector is reinstalled e Tighten the 9 16 in lock nut f Reinstall the air deflector and close the left front door of the MS detector Make sure that the frequency cursor is...

Страница 129: ...cing The following symptoms suggest that the electron multiplier may need replacing Excessive noise in the mass spectrum Inability of the multiplier gain calibration procedure to achieve a gain of 3 105 electrons per ion with an electron multiplier voltage less than or equal to 2 5 kV You can read the current value of the electron multiplier voltage in the Ion Detection System dialog box which can...

Страница 130: ...e of the vacuum manifold 5 With one hand hold the high voltage tube and with the other hand hold the electron multiplier support Then detach the high voltage tube from the high voltage feedthrough in the top cover plate and remove the electron multiplier as a unit The anode remains in the anode feedthrough in the top cover plate See Figure 5 10 6 Remove the anode from the anode feedthrough by unsc...

Страница 131: ..._________ 5 25 Figure 5 10 Electron multiplier exploded view assembled view top cover view Electron Multiplier Shield Cathode Spring Washer High Voltage Ring High Voltage Tube Electron Multiplier Assembled Electron Multiplier Top Cover Electron Multiplier Anode High Voltage Feedthrough Support Plate ...

Страница 132: ...and the support plates should remain attached to the top cover plate c Turn the assembly over With a Phillips screwdriver remove the two screws that secure the electron multiplier shield to the high voltage ring d Remove the electron multiplier shield and cathode from the high voltage ring e Insert the narrow end of a new cathode P N 00022 02400 first through the spring washer and then through the...

Страница 133: ...phs tab c In the Set Device Value option box select Multiplier V d In the text box to the right of the Set Device Value option box enter 800 e Click on Set to set the electron multiplier voltage to 800 V f Click on OK to return to Tune Plus 15 Calibrate the electron multiplier voltage as follows a Allow the system to pump down for at least one hour before you turn on the high voltages b Set up for...

Страница 134: ... following Did the system fail when you were running samples Did problems occur after you performed maintenance on the instrument data system or peripherals Did you change the system s configuration cables or peripherals just before the problem occurred If the answer is yes to the first item above there is the possibility of a hardware failure and running the diagnostics is appropriate If the answ...

Страница 135: ...on Start to start the diagnostics XP Plus starts testing and displays a chronological log of all diagnostic tests in the Testing text box Once testing for a specific subsystem is completed XP Plus displays either Pass or Fail in the Results group box If the Tune Plus diagnostics indicates a problem perform the maintenance procedure indicated by the Tune Plus diagnostics For more information on the...

Страница 136: ...n What to Test Group Box Scanning Device Number in Graph View Scanning Device Name Status n a Refer to Table A 1 in the Appendix for static details RF 1 03 readback number 06 Aux amplitude V 0 to 83 2 RF 2 10 Main RF DAC 16 bit 0 to 65535 RF 3 11 readback number 50 Vernier det RF amp V 0 to 65535 RF 4 11 readback number 51 Vernier RF DAC 16 bit 0 to 65535 RF 5 25 readback number 52 Octapole RF DAC...

Страница 137: ...use Circuit Description P N System Control PCB F1 Multipoles and tube lens power supplies ion gauge grid 0 25 A time lag 5 x 20 mm 250 V 00006 01700 System Control PCB F2 Multipoles and tube lens power supplies 0 25 A time lag 5 x 20 mm 250 V 00006 01700 System Control PCB F3 Ion transfer capillary multipoles and mass analyzer DC offsets 0 16 A time lag 5 x 20 mm 250 V 00006 01700 System Control P...

Страница 138: ...zer Auxiliary PCB go to step 5 RF Voltage Amplifier PCB F1 36 V 1 0 A quick act 5 x 20 mm 250 V 00006 07610 RF Voltage Amplifier PCB F2 28 V 0 5 A quick act 5 x 20 mm 250 V 00006 07608 Analyzer Auxiliary PCB F1 28 V 1 6 A quick act 5 x 20 mm 250 V 00006 08610 Analyzer Auxiliary PCB F2 36 V 1 6 A quick act 5 x 20 mm 250 V 00006 08610 Power Module F1 Voltage select switch 3 5 A time lag 5 x 20 mm 25...

Страница 139: ...back about 1 25 cm 0 5 in and then pull it out and away from the MS detector b Remove the System Control PCB protective cover as follows i With a Phillips screwdriver loosen the five screws that hold the protective cover to the MS detector chassis ii Pull the cover up and out of the guide slots on the MS detector chassis c Locate and replace the defective fuse on the System Control PCB with a fuse...

Страница 140: ...fier PCB a With a Phillips screwdriver loosen the eight screws that hold the metal cover to the RF Voltage Amplifier PCB Remove the cover b Locate and replace the defective fuse on the RF Voltage Amplifier PCB with a fuse of the same type voltage and current rating Refer to Table 5 5 c Place the metal cover over the RF Voltage Amplifier PCB With a Phillips screwdriver tighten the eight screws that...

Страница 141: ...the top of the Analyzer Auxiliary PCB Three coaxial cables come from the Analyzer PCB one coaxial cable comes from the Waveform DDS PCB in the embedded computer one coaxial cable comes from the Waveform Amplifier PCB one 7 lead cable comes from the System Control PCB and one 4 lead cable comes from the 36 V power supply 6 Reinstall the top cover of the MS detector as described in the topic Reinsta...

Страница 142: ...PCB RF Voltage Amplifier PCB Replacing the System Control PCB Replacing the RF Voltage Control PCB Replacing the Low Pass Filter PCB CAUTION With the electronics service switch in the Service Position the system is still under vacuum Power is still supplied to the rotary vane pump Turbomolecular Pump Controller turbomolecular pump turbomolecular pump fan 24 V keep alive power supply vent valve and...

Страница 143: ...r The following PCBs and switching power supply assemblies are installed in the tower See Figure 5 13 5 V 15 V 24 V dc and 36 V 28 V dc switching power supplies Turbomolecular Pump Controller 48V 24V switching power supply 8 kV power supply Power Module Note To service the Power Module you need to remove the tower System Control PCB and embedded computer Do not service the Power Module unless you ...

Страница 144: ...______________ 5 38 ___________________LCQ Deca XP Plus Hardware Manual ________________ Figure 5 13 Tower embedded computer removed 36 V 28 V DC Switching Power Supply 5 V 15V 24 V DC Switching Power Supply Turbomolecular Pump Controller 48 V Power Supply Power Module 8 kV Power Supply ...

Страница 145: ...d computer d Lift the embedded computer and reposition it such that the two hooks in the back of the embedded computer box insert into the two slots in the MS detector chassis See Figure 5 14 on page 5 44 for the location of the slots To replace the switching power supply assembly which includes the 5 V 15 V 24 V dc and 36 V 28 V dc switching power supplies go to step 4 To replace the Turbomolecul...

Страница 146: ...fastener that holds the switching power supply assembly to the tower l Reconnect the cable that is connected to the reset button cable m Reconnect the two cables to the Power Module to the two upper connectors on the Power Module n Reconnect the cable that is connected to the fan cable o Reconnect the cable to the Waveform Amplifier PCB to the connector on the Waveform Amplifier PCB p Reconnect th...

Страница 147: ... that comes from the Power Module l Reconnect to the Turbomolecular Pump Controller the thick cable that goes to the turbomolecular pump m Go to step 7 6 To replace the 8 kV power supply proceed as follows a Disconnect from the 8 kV power supply the cable that comes from the API panel b Disconnect from the rear of the System Control PCB at J5 the thick cable that goes to the System Control PCB c L...

Страница 148: ...fold base plate and chassis f Reconnect the cables that connect to the top of the embedded computer See Figure 5 14 on page 5 44 and Figure 5 15 on page 5 47 8 Reinstall the top cover of the MS detector as described in the topic Reinstalling the Top Cover of the MS Detector on page 5 16 9 Close the front doors of the MS detector 10 Restart the system as described in the topic Starting Up the Syste...

Страница 149: ...ers that hold the front cover to the embedded computer Remove the front cover of the embedded computer 4 Locate the PCB you want to replace See Figure 5 14 5 Disconnect all electrical cables to the PCB that you want to replace 6 With a Phillips screwdriver remove the screw that holds the PCB to the card cage CAUTION Make sure that the XP Plus electronic service switch is in the Service Position or...

Страница 150: ...es in the Tower _____________________________________ 5 44 ___________________LCQ Deca XP Plus Hardware Manual ________________ Figure 5 14 Embedded computer with front cover removed Ethernet PCB Acquisition DSP Control DSP CPU PCB Waveform DDS PCB ...

Страница 151: ...the PCB that you replaced 12 Reinstall the front cover of the embedded computer Tighten by hand the two fasteners that hold the front cover to the embedded computer 13 Close the front doors to the MS detector 14 Place the electronics service switch in the Operating Position 15 Run the Tune Plus diagnostics to verify that the system is operational Replacing the Vent Delay PCB and Backup Battery Ion...

Страница 152: ...river loosen the four screws that secure the Vent Delay PCB to the MS detector chassis Remove the Vent Delay PCB d Unpack the new Vent Delay PCB P N 97000 61370 Retain the packing materials so that you can pack and ship the defective PCB to the Thermo Finnigan Repair Center in San Jose Be sure to note the apparent problem or symptoms on the enclosed forms e Replace the battery P N 00301 05720 if n...

Страница 153: ...loosen the fitting to the vent valve solenoid Remove the vent valve c Replace the old vent valve with a new one P N 97000 60128 d With a 7 16 in open end wrench tighten the fitting to the vent valve solenoid Figure 5 15 PCBs and assemblies that are accessible from the top of the MS detector Conversion Dynode and Electron Multiplier Combo Power Supply Vent Delay PCB And Battery Backup Supply Ion Ga...

Страница 154: ...ystem Shutdown Startup and Reset chapter Replacing the Electron Multiplier and Conversion Dynode Power Supplies Analyzer PCB Analyzer Auxiliary PCB Waveform Amplifier PCB RF Voltage Amplifier PCB The electron multiplier power supply conversion dynode power supply Analyzer PCB Analyzer Auxiliary PCB Waveform Amplifier PCB RF Voltage Amplifier PCB and battery battery backup are accessible from the t...

Страница 155: ...ier power supply c Disconnect from the top of the electron multiplier and conversion dynode power supplies the electrical cable that comes from the System Control PCB d Loosen by hand or with a Phillips screwdriver the two fasteners that hold the electron multiplier and conversion dynode power supply module to the MS detector chassis e Carefully lift the electron multiplier and conversion dynode p...

Страница 156: ...tron multiplier high voltage cable that comes from the electron multiplier power supply f Use a 7 16 in open end wrench to disconnect the helium damping gas line from the fitting g With a Phillips screwdriver remove the metal cover from the Analyzer PCB h With a Phillips screwdriver remove the screws that hold the Analyzer PCB to the top cover plate of the vacuum manifold i Unseat and remove the A...

Страница 157: ...les to the Analyzer Auxiliary PCB b With a Phillips screwdriver remove the metal cover from the Analyzer Auxiliary PCB c With a Phillips screwdriver remove the screws that hold the Analyzer Auxiliary PCB to the top of the vacuum manifold Remove the Analyzer Auxiliary PCB d Unpack the new Analyzer Auxiliary PCB P N 97000 61340 Retain the packing materials so that you can pack and ship the defective...

Страница 158: ...ms on the enclosed forms e Install the new PCB in the place occupied by the old PCB f With a Phillips screwdriver reinstall the screws that secure the Waveform Amplifier PCB to the top of the tower g Reinstall the metal cover to the top of the Waveform Amplifier PCB h Reconnect all cables to the Waveform Amplifier PCB that you disconnected in step 6a i Go to step 8 7 To replace the RF Voltage Ampl...

Страница 159: ...ce the electronics service switch in the Operating Position 10 Run the Tune Plus diagnostics to verify that the system is operational 11 If you replaced the Analyzer PCB Analyzer Auxiliary PCB or RF Voltage Amplifier PCB tune the ring electrode and quadrupole octapole RF voltages as described in the topic Tuning the Ring Electrode and Quadrupole Octapole RF Voltages on page 5 16 Replacing the Syst...

Страница 160: ...es to the System Control PCB The following cables are connected to the System Control PCB Ion gauge Convectron gauge P9 Front panel P2 Analyzer J3 Spray shield J6 RF and waveform amplifiers P12 Analyzer Aux P5 Electron multiplier conversion dynode power supplies P3 RF control P8 LC I O P4 Switching power supplies J2 APCI heater J4 Transformer XMFR P1 High speed serial P6 backside of PCB 8 kV power...

Страница 161: ...S detector chassis 12 Reconnect all cables to the System Control PCB The following cables are connected to the System Control PCB Ion gauge Convectron gauge P9 Front panel P2 Analyzer J3 Spray shield J6 RF and waveform amplifiers P12 Analyzer Aux P5 Electron multiplier conversion dynode power supplies P3 RF control P8 LC I O P4 Switching power supplies J2 APCI heater J4 Transformer XMFR P1 High sp...

Страница 162: ... 5 in until the studs on the cover lock in the guide slots c Tighten by hand the fastener that secures the side cover to the chassis of the MS detector 15 Reinstall the top cover of the MS detector as described in the topic Reinstalling the Top Cover of the MS Detector on page 5 16 16 Place the electronics service switch in the Operating Position 17 Run the Tune Plus diagnostics to verify that the...

Страница 163: ...RF Voltage Control PCB and its housing proceed as follows See Figure 5 16 for the location of the RF Voltage Control PCB 1 Place the electronics service switch in the Service Position or shut down and vent the XP Plus system as described in the topic Shutting Down the System Completely in the System Shutdown Startup and Reset chapter Figure 5 16 Left side of the MS detector showing the RF Voltage ...

Страница 164: ... PCB and its housing as a unit Reinstall the cover plate on the housing 8 Unpack the new RF Voltage Control PCB and housing P N 96000 61100 Retain the packing materials so that you can pack and ship the defective PCB and housing to the Thermo Finnigan Repair Center in San Jose Be sure to note the apparent problem or symptoms on the enclosed forms 9 Position the new RF Voltage Control PCB and its h...

Страница 165: ...g the Top Cover of the MS Detector on page 5 16 16 Place the electronics service switch in the Operating Position 17 Run the Tune Plus diagnostics to verify that the system is operational Replacing the Low Pass Filter PCB To replace the Low Pass Filter PCB proceed as follows See Figure 5 17 for the location of the Low Pass Filter PCB 1 Place the electronics service switch in the Service Position o...

Страница 166: ...k and ship the defective PCB to the Thermo Finnigan Repair Center in San Jose Be sure to note the apparent problem or symptoms on the enclosed forms 8 Position the new Low Pass Filter PCB in the place that was occupied by the old PCB With a Phillips screwdriver reinstall the screws that hold the Low Pass Filter PCB to the fan low pass filter vent control assembly 9 Position the metal cover over th...

Страница 167: ...MS detector such that the screws in the MS detector chassis insert into the guide slots on the rear cover b Slide the rear cover down about 1 2 cm 0 5 in until the screws lock in the guide slots on the cover c With a Phillips screwdriver tighten the ten screws that secure the rear cover to the chassis of the MS detector 12 Reinstall the top cover of the MS detector as described in the topic Reinst...

Страница 168: ...the MS detector by loosening the 1 4 in Allen screw on the right front door with an Allen wrench Disconnect any sample tubes between the syringe pump and the API source before opening the right front door 3 Remove the top cover of the MS detector as described in the topic Removing the Top Cover of the MS Detector on page 5 6 4 Loosen the hose clamp that secures the vacuum hose to the tee P N 97144...

Страница 169: ..._____ Replacing the Turbomolecular Pump __________________ LCQ Deca XP Plus Hardware Manual _________________ 5 63 Figure 5 18 Turbomolecular pump Convectron Gauge Turbomolecular Pump Rails Turbomolecular Pump Power Cable Vacuum Hose Clamp Triple Forelines Union ...

Страница 170: ...en the two Allen screws that hold the rails and turbomolecular pump to the vacuum manifold Do not overtighten the screws 5 Reconnect the vacuum hose to the tee P N 97144 20031 Tighten the hose clamp that secures the vacuum hose to the tee 6 Reconnect the turbomolecular pump power cable to the turbomolecular pump controller 7 Reinstall AT box 8 If necessary reconnect the vacuum hoses to the forelin...

Страница 171: ...he oil in the rotary vane pump proceed as follows 1 Turn off the flow of sample solution from the LC to the MS detector 2 From the Tune Plus window choose Control Standby or click on the On Standby button to put the MS detector in Standby 3 Withdraw the API flange from the spray shield and place a septum over the entrance to the ion transfer capillary 4 Open the gas ballast valve on the rotary van...

Страница 172: ......

Страница 173: ...umbers for replaceable and consumable parts for the MS detector data system and kits To ensure proper results in servicing the LCQ Deca XP Plus system order only the parts listed or their equivalent For information on how to order parts refer to the topic Replaceable Parts in the LCQ Deca XP Plus Preinstallation Requirements Guide ...

Страница 174: ...urbomolecular pump Rotary vane pumps Vacuum system assemblies Mechanical assemblies Electrical assemblies Printed circuit boards PCBs RF control detection assemblies Cables Covers ESI Probe Assembly Assembly ESI Probe 97144 60060 Container shipping ESI and API Probes XP 00707 10012 Cover port view 97144 20019 Ferrule 0 008 in ID KEL F HPLC 00101 18114 Ferrule 0 016 in ID PEEK HPLC 00101 18120 Ferr...

Страница 175: ...ng fused silica 0 1 mm ID 0 190 mm OD 6 ft 1 8 m l 00106 10499 Tubing fused silica 0 1 mm ID 0 363 mm OD deactivated 1 m l 00106 10504 Union ground 97144 20016 Assembly Slide ESI Orthogonal 97144 60070 Frame slide ESI orthogonal 97144 20015 Plate slide ESI orthogonal 97144 20013 Screw flat Phillips 4 40 3 8 in stainless steel 00407 44006 Bal Seal 2 0 in ID light load API2 00107 18010 Seal slide ES...

Страница 176: ...g 1 239 in ID 1 16 in thick Viton 00107 05903 O ring 3 73 in ID 0 103 in thick Viton 00107 10058 O ring 3 239 in ID 0 070 in thick Viton 00107 13448 O ring 2 489 in ID 0 070 in thick Viton 00107 15527 Screw flat pan head 2 56 3 8 in stainless steel 00407 03200 Screw flat socket 6 32 3 8 in stainless steel 00452 90042 Screw socket 6 32 1 in long stainless steel 00419 63216 Thumb screw flange orthog...

Страница 177: ...312 in OD 0 03 in thick stainless steel 00470 00410 Assembly Corona APCI Orthogonal 97144 60090 Connector receptacle HV shielded 00004 89626 Contacting socket Be Cu 70001 30016 Corona tube APCI 97144 20027 Needle housing corona tube APCI 97144 20028 Needle corona APCI 70005 98033 O ring 0 250 in ID 1 16 in thick Viton 00107 04000 Resistor fixed carbon composite 1 4 W 22 MΩ 5 00015 27820 Screw set ...

Страница 178: ...5 in ID 3 16 in thick Viton 00107 14100 O ring 0 30 in ID D 0 064 W Kalrez compound 4079 00107 12750 Plunger ball 6 40 0 310 long 1 lb ft 00201 11719 Screw set socket HD 6 32 5 8 in stainless steel 8311 0610 Screw pan head Phillips 4 40 1 4 in stainless steel 00415 44004 Screw Socket 6 32 3 8 in stainless steel 00419 63206 Seal graphite source heater 70111 20216 Seal insulator spray shield 97144 2...

Страница 179: ... trap 97044 20005 Nipple damping gas 96000 20117 Nut 97000 20339 Post 97000 20338 Sleeve entrance lens 97044 20002 Sleeve exit lens 97044 20001 Spacer ring 97000 20302 Spring washer 0 33 in ID 0 49 in OD stainless steel 00474 11618 Tubing Teflon 14 gauge 0 016 in wall thickness 00007 94320 Ion Detection System Electron Multiplier Conversion Dynode Disk shield dynode 97000 20263 Shield dynode 97000...

Страница 180: ...0 731 in OD 0 588 in ID 00471 50080 Top Cover Plate of Vacuum Manifold Assembly Top Cover 97144 60190 Connector Swagelok modified 96000 30005 Fitting Swagelok ferrule 1 8 in tee set 00101 09250 Fitting Swagelok nut knurled 1 8 in brass 00101 12902 Nipple damping gas 96000 20117 Pin guide large top cover 97000 20267 Pin guide top cover 97000 20222 Pin PCB top cover 97000 20223 Plate top manifold 97...

Страница 181: ... 00108 09001 Clamp hose adjustable 9 16 in to 1 1 16 in stainless steel screw 00108 10016 Elbow turbo exhaust 70111 20104 Hose adapter 25 mm 00108 09005 Hose 1 2 in diameter steel reinforced 00301 24155 Hose 1 in diameter embedded poly spiral 00301 24141 Screw socket cap m4 20 mm black oxide 00419 63222 Tee hose 1 in 1 in 1 2 in aluminum 97144 20031 Union duo forelines 90 degrees 97000 20294 Vacuu...

Страница 182: ...id 97000 98001 Assembly Turbomolecular Pump Controller 97144 60040 Frequency converter Leybold TPS 00108 10012 Power supply switch 24 V 85 A 48V 4 A 400 W 00012 24208 Assembly Power Module 97044 60050 Circuit breaker 15 A double pole high in rush 00019 00522 Circuit breaker 2 pole 10 A 230 V ac unmarked rocker 00019 00508 Connector panel power inlet IEC 320 C20 00004 89660 Filter line 20 A screw t...

Страница 183: ...B Low Pass Filter 97000 61380 PCB RF Voltage Amplifier 96000 61090 Fuse 0 50 A 5 20 mm 250 V quick acting F2 00006 07608 Fuse 1 00 A 5 20 mm 250 V quick acting F1 00006 07610 PCB RF Voltage Control 96000 61100 PCB Syringe Pump Switch 97000 61410 PCB System Control 97144 61015 Fuse 0 16 A 5 20 mm 250 V time lag F1 F4 00006 01700 Fuse 0 25 A 5 20 mm 250 V time lag F7 00006 11204 Fuse 0 40 A 5 20 mm ...

Страница 184: ...onvectron gauge 97000 63001 Cable API front panel APCI heater 97033 63210 Cable I O PanelPCB Divert Valve Select PCB ribbon 97000 63011 Cable System Control PCB I O Panel PCB ribbon 97000 63013 Cable System Control PCB RF Voltage Control PCB ribbon 97000 63015 Cable System Control PCB Conversion Dynode Power Supply PCB 15 kV Electron Multiplier Power Supply PCB 97000 63016 Cable Electron Multiplie...

Страница 185: ... Cable System Control PCB RF Voltage Amplifier PCB Waveform Amplifier PCB ribbon 97000 63048 Cable System Control PCB Analyzer Auxiliary PCB ribbon 97000 63049 Cable System Control PCB spray shield panel interconnect 97000 63050 Cable APCI control safety interlock 97144 63040 Covers Cover Analyzer PCB small 97000 98033 Cover Analyzer Auxiliary PCB 97000 10088 Cover end cap balun shield 96000 98013...

Страница 186: ...__ 6 14 ___________________LCQ Deca XP Plus Hardware Manual ________________ 6 2 Data System Hardware Kit Data System Hardware 97044 62111 Cable thinwire Ethernet coax with ferrite damper 97044 63060 Connector T Connector thinwire Ethernet 00012 50967 Terminator thinwire Ethernet 00950 00918 ...

Страница 187: ...micals Kit __________________LCQ Deca XP Plus Hardware Manual _________________ 6 15 6 3 Chemicals Kit Kit Chemicals 97000 62042 Caffeine 1 mg mL in methanol 00301 12310 Reserpine 1 gram 00301 12901 Sample Met Arg Phe Ala MRFA solids 20 mg each 40061 60002 Ultramark 1621 m s 00301 12200 ...

Страница 188: ...gelok nut 1 8 in brass 2 each 00101 15500 Fitting tee 1 in barbed 1 each 00102 10120 Fuse 0 16 A 5 20 mm 250 V time lag 8 each 00006 01700 Fuse 0 25 A 5 20 mm 250 V time lag 2 each 00006 11204 Fuse 0 40 A 5 20 mm 250 V time lag 4 each 00006 05080 Fuse 0 50 A 5 20 mm 250 V quick acting 2 each 00006 07608 Fuse 1 00 A 5 20 mm 250 V quick acting 2 each 00006 07610 Fuse 1 60 A 5 20 mm 250 V quick actin...

Страница 189: ... 15 ft 4 5 m l 00101 50100 Tubing fused silica 0 150 mm ID 0 390 mm OD 2 ft 0 6 m l 00106 10498 Tubing fused silica 0 050 mm ID 0 190 mm OD 6 ft 1 8 m l 00106 10502 Tubing fused silica 0 1 mm ID 0 4 mm OD deactivated 3 ft 1 m 00106 10504 Tubing fused silica 0 1 mm ID 0 190 mm OD 6 ft 1 8 m l 00106 10499 Tubing PVC unreinforced clear 3 8 in ID 10 ft 3 m l 00301 22895 Tubing PEEK red 0 005 in ID 1 1...

Страница 190: ...Fuse 0 50 A 5 20 mm 250 V quick acting 00006 07608 Fuse 1 00 A 5 20 mm 250 V quick acting 00006 07610 Fuse 1 60 A 5 20 mm 250 V quick acting 00006 08610 Fuse 2 50 A 5 20 mm 250 V Type F 00006 11202 Fuse 2 50 A 5 20 mm 250 V time lag 00006 09510 Fuse 3 15 A 5 20 mm 250 V time lag 00006 10510 Hinge open 180 degree 00250 08003 Nut hex KEP 6 32 cadmium plated 00460 16321 Nut hex KEP 8 32 stainless ste...

Страница 191: ...ot 6 32 1 4 in cadmium plated 00404 63204 Stud ball 6 32 0 375 in 00201 12110 Switchcap manifold cover interconnect 97000 40009 Switchcap right door interconnect 97000 40010 Tubing Teflon 18 gauge 0 016 in wall thickness 00007 94330 Valve assembly sheath aux gas dual manifold 00110 20014 Washer flat 6 stainless steel 00472 00600 Washer interlock 5 16 in ID stainless steel 00479 04400 ...

Страница 192: ...PLC 1 16 in stainless steel Valco 00101 18122 Syringe adapter 1 16 in fill port liner ferrule Valco 00110 16002 Syringe adapter 1 16 in fill port Valco 00110 16000 Valve replacement nut 1 16 in HPLC stainless steel 00110 16008 Valve replacement rotor seal Valco 00110 16006 Valve replacement stator Valco 00110 16004 5 µL sample loop stainless steel Valco 00110 16010 20 µL sample loop stainless stee...

Страница 193: ...lus Hardware Manual _________________ 6 21 6 7 Optional Tools Hexdriver 0 28 in 00025 01810 Hexdriver 0 35 in 00025 08041 Tool pin extractor AMP large 00725 00013 Tool pin extractor AMP small 00725 00020 Wrench Allen hex drive 1 4 in with handle 00725 00015 Tool capillary removal 70111 20258 Tool removal needle seal 70005 20304 ...

Страница 194: ......

Страница 195: ...__________________ LCQ Deca XP Plus Hardware Manual __________________ A 1 Appendix A Troubleshooting Appendix A provides a flowchart and tables that can be used to troubleshoot the LCQ Deca XP Plus ...

Страница 196: ... true Front panel Power LED is green Front panel divert inject valve Load LED is On Front panel Communication LED goes from yellow to green 3 Wait 3 min for the system to download Are the following true Front panel System LED is On Front panel Vacuum LED is On Xcalibur data system is in Standby 3 Run diagnostics See the Diagnostics and PCB Replacement Specified diagnostics all pass Diagnose scan p...

Страница 197: ...nd of both mechanical pumps Check Main Power circuit breaker switch and AC power outlets 2 Pump cooling fan is On Check for sound of fans Check for cooling air through the rear dust filter and I O panel side vent Check fan cables and 24 V power supply 3 Turbomolecular pump is On Open front panel doors and listen for the spin up sound of the turbomolecular pump Check turbomolecular pump pump contro...

Страница 198: ... LED remove right side cover is On Check 5 V dc power supply and associated cables check AC power from electronics service switch to 5V dc power supply Check Divert Inject Valve LED PCB I O Panel PCB and associated cables Check power cables to System Control PCB 0 10 Embedded computer checks DRAM then the CPU PCB BIOS starts Same as above See above 0 21 CPU PCB runs PSOS Boot Loader from Flash dri...

Страница 199: ... PCB If necessary replace Ethernet PCB and update Ethernet address in data system computer 0 30 X86 EXECTask application resets Control DSP PCB Control DSP PCB embedded computer RESET LED is red See Figure 5 14 Waveform DDS PCB embedded computer RESET LED is green System Control PCB remove right side cover RESET LED is Off Check cables in Embedded Computer check Control DSP PCB Check Waveform DDS ...

Страница 200: ...s initialization Vacuum LED front LED panel is green System Control PCB high voltage relay clicks Check ribbon cable from System Control PCB to front LED panel check data system computer for error messages If necessary replace Control DSP PCB 2 22 XP Plus in standby mode and ion gauge is On System LED front LED panel is yellow Data system computer screen displays Instrument in Standby Check ribbon...

Страница 201: ...D panel LEDs are green except Syringe LED which is off and Scan LED which is blue Scan LED front LED panel blinks to Total Microscans spin box value in Define Scan dialog box Control DSP PCB LED blinks Acquisition DSP PCB LED blinks Waveform DDS PCB LED blinks High Voltage Power Supply ON EM LED visible with left front panel open blinks to Total Microscans spin box value One High Voltage Power Sup...

Страница 202: ...stigate each readback failure check associated fuses cables modules See Table 4 Diagnostics details for signal paths and potential repair locations 4 Insert contact closure test plug into Peripheral Control terminal See next column for test plug wiring Choose Diagnostics Diagnostics in Tune Plus Select Graphs tab Select Contact closure test in Test Type list box Select Start Skip this step if Peri...

Страница 203: ...terminal I O Panel is not used Check for normal voltage 0 to 1 0 V Investigate each readback failure check associated fuses cables and modules See Table 4 Diagnostics details for signal paths and potential repair locations 7 Select Status View in Tune Plus Scroll to DIGITAL INPUTS STATUS Press the Divert Inject Valve switch front panel Divert Inject LEDs toggle between Load and Inject Divert Injec...

Страница 204: ... 5DWH PLQ QIXVHG 9ROXPH 6 ULQJH LDPHWHU PP Syringe LED front panel is green Feel syringe pump pulsate Investigate each readback failure check associated fuses cables and modules Investigate the following signal paths and potential repair locations Syringe Pump cables I O PCB Syringe Control PCB System Control PCB Table A 3 Data system diagnostics continued Step User Input or Action Normal Conditio...

Страница 205: ...able Sys Ctrl PCB both 23 SOURCE Capillary Voltage Capillary assy cable Sys Ctrl PCB static 28 SOURCE Capillary Temp Capillary heater assy cable Sys Ctrl PCB static 09 VACUUM Ion Gauge 10E 5 Torr Ion Gauge cable Sys Ctrl PCB static 11 VACUUM Convectron gauge Torr Convectron Gauge cable Sys Ctrl PCB both 30 ION OPTICS Octapole 1 Offset V Octapole 1 Top Cover PCB cable Sys Ctrl PCB both 01 ION OPTIC...

Страница 206: ...ss RF PCB cable Sys Ctrl PCB static 26 SUPPLIES 35V Supply Voltage V From toroidal transformer static 31 SUPPLIES 36V Supply Voltage V PS1 Harness RF PCB cable Sys Ctrl PCB static 38 SUPPLIES 150V Supply Voltage Xfrmr or Linear Supply Harness Sys Ctrl PCB static 24 SUPPLIES 150V Supply Voltage Xfrmr or Linear Supply Harness Sys Ctrl PCB static 42 SUPPLIES 205V Supply Voltage Xfrmr or Linear Supply...

Страница 207: ...9 wrench flats caution 4 13 APCI probe assembly changing 2 1 corona discharge needle 1 9 cross sectional view figure 1 11 1 12 description 1 8 disassembling 4 13 flange 1 8 installing 2 8 reassembling 4 17 removing 2 2 replaceable parts 6 4 APCI sample tube connection figure 4 15 installing 4 16 length 4 17 position figure 4 17 removing 4 15 replacement note 4 17 replacing 4 11 APCI slide assembly...

Страница 208: ... 10 spring in extension mount 4 31 chemicals disposal of CAUTION 4 4 5 4 chemicals kit replaceable parts 6 15 cleaning procedures APCI probe components 4 11 4 14 APCI probe flushing 4 6 API probe 4 6 API stack components 4 33 conversion dynode 5 15 electron multiplier 5 15 ESI probe components 4 18 ESI probe flushing 4 6 frequency 4 5 5 4 ion detection system 5 15 ion optics 5 5 ion transfer capil...

Страница 209: ... 5 42 Low Pass Filter PCB location figure 5 60 Low Pass Filter PCB replacing 5 59 replaceable parts 6 10 RF Voltage Amplifier PCB replacing 5 48 RF Voltage Control PCB location figure 5 57 RF Voltage Control PCB replacing 5 57 System Control PCB replacing 5 53 Turbomolecular Pump Controller replacing 5 37 Vent Delay PCB replacing 5 45 Waveform Amplifier PCB replacing 5 48 Waveform DDS PCB location...

Страница 210: ...0 ESI probe exploded view 4 22 ESI process 1 6 ESI spray nozzle 4 25 Graph view quadrupole octapole RF voltage tuning 5 19 Graph view ring electrode RF voltage modulation tuning 5 20 Graph view ring electrode RF voltage tuning 5 21 ion optics 1 17 left side of MS detector 5 57 Low Pass Filter PCB location 5 60 mass analyzer and ion optics 5 8 power panel 3 2 System Control PCB 5 33 top cover plate...

Страница 211: ... MS detector startup 3 7 left side cover reinstalling 5 59 removing 5 58 left side of MS detector figure 5 57 liquid chromatograph LC solvent flow turning off 3 3 Low Pass Filter PCB location figure 5 60 replacing 5 59 M main power circuit breaker MS detector components On Off status 3 10 main power circuit breaker switch location figure 3 2 maintenance APCI probe 4 11 APCI probe components cleani...

Страница 212: ... 1 NSI source assembly description 1 13 flange 1 13 O octapole leads location figure 5 8 octapoles dc offset voltage 1 17 description 1 17 On Off status table 3 10 RF voltage 1 17 RF voltage tuning 5 16 Off condition MS detector components status 3 10 O rings ESI probe location figure 4 25 P PCBs accessible from top of MS detector figure 5 47 Acquisition DSP PCB location figure 5 44 Acquisition DS...

Страница 213: ...5 37 5 V 15 V 24 V dc switching power supply 5 37 8 kV power supply 5 37 Acquisition DSP PCB 5 42 Analyzer Auxiliary PCB 5 48 Analyzer PCB 5 48 anode electron multiplier 5 23 battery backup 5 48 cathode electron multiplier 5 23 Control DSP PCB 5 42 conversion dynode power supply 5 48 CPU PCB 5 42 electron multiplier 5 23 electron multiplier power supply 5 48 embedded computer PCBs 5 42 Ethernet PC...

Страница 214: ... location figure 1 15 4 30 4 35 spray shield cleaning 4 34 description 1 14 flushing 4 8 location figure 1 15 4 30 4 32 Standby condition MS detector components status 3 10 placing system in 3 3 startup MS detector 3 6 operating conditions setting 3 7 supplies MS detector maintenance 4 3 5 3 switching power supplies replacing 5 37 syringe pump On Off status table 3 10 replaceable parts 6 8 system ...

Страница 215: ...m assemblies replaceable parts 6 9 vacuum hose clamp location figure 5 63 Vacuum LED note 3 7 vacuum manifold cleaning note 5 15 top cover plate reinstalling 5 15 top cover plate removing 5 6 vacuum pumps turbomolecular pump replacing 5 62 vacuum system On Off status table 3 10 replaceable parts 6 9 valve accessories replaceable parts 6 20 vaporizer APCI probe description 1 9 casing location figur...

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