Page 9 of 12
TangenX
TM
SIUS
TM
PD Filter Plate & 2-Bolt Clamp Assembly
User Guide
Identification
IF.PUG.019
Revision
R2
Approved
20-DEC-2018
2.
Remove from clamp the following: Isolation Plate, all gaskets, all cassettes and Filter Plate
Insert.
3.
Wipe down any spillage from clamp components.
4.
Store clamp top plate on clamp base (or other location) along with nuts, washers and spacers.
FOR TRADITIONAL SANITARY HARDWARE SYSTEM:
To clean the TFF system following use,
recirculate 0.5M sodium hydroxide through the system with all valves open. Cassettes are left in
place during the system cleaning procedure to provide a flow path for the cleaning solution.
Alternatively the cassettes may be removed and replaced with a CIP spacer gasket (see Figure 1.1).
Upon completion of the cleaning cycle, flush the system with WFI, or DI water prior draining and
discarding the cassettes. Table 9.1 lists possible recommended cleaning solutions.
Table 9.1 Recommended cleaning solutions
CLEANING AGENT
CLEANING CONDITIONS
0.5N Sodium Hydroxide
Contact Time
Temperature
= 35°C (95°F)
1.5% Alconox® Detergent
Contact Time
= 30 - 60 minutes
Temperature
= 40°C (104°F)
TX047 Process Scale EPDM Clean-in-Place Gasket (5 pk)
TX048 Process Scale Silicone Clean-in-Place Gasket (5 pk)