GE Analytical Instruments ©2006
7-9
DML 14291 Rev. A
Pietropauoli, A.P., Perillo, I.B., Torres, A., Perkins, P.T., Frasier, L.M.,
Utell, M.J.,
Frampton, M.W., and Hyde, R.W. “Simultaneous Measurement of Nitric
Oxide Production by Conducting and Alveolar Airways of Humans.” J Appl
Physiol 1999; 87(4): 1532- 1542.
Silkoff P.E., Sylvester J.T., Zamel N., and Permutt S. “Airway Nitric Oxide
Diffusion in Asthma: Role in Pulmonary Function and Bronchial
Responsiveness.” Am J Respir Crit Care Med 2000; 161(4 Pt 1): 1218-28.
Jörres, R. A. “Modeling the production of nitric oxide within the human
airways.” Eur. Respir. J. 2000, 16: 555-560.
Cleaning the Accurate NO Breath Kit and Flowmeter
The procedures for cleaning the non-rebreathing valve, restrictor and tubing are
outlined below. Consult your institution’s infection control procedure for
recommended frequency For the valve and flowmeter, avoid using denatured
alcohol or alcohol based solutions as they may cause cracking. Also, avoid
temperatures in excess of 45 °C (113 °F). Autoclaving, pasteurization, and
ethylene oxide gas sterilization are not recommended. Do not try to clean or
sterilize the inspiratory gas filter or Tedlar bag.
Disassemble the Valve
Remove the flowmeter and inspiratory gas filter or Tedlar bag from the breath kit.
To clean the breath kit, start by disassembling all of the components:
•
Remove the mouthpiece from the modified mouth port and unscrew the mouth
port from the valve body.
•
Remove the restrictor from the Luer adapter and unscrew the modified
exhalation port.
•
Remove the exhalation diaphragm from the valve and remove the diaphragm
from its ring.
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