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NeuroMuscular Transmission Module, M-NMT
Document No. 800 1018-1
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FUNCTIONAL DESCRIPTION
2.1
Measurement principle
2.1.1
Nerve stimulation
There are three stimulus modes in the NeuroMuscular Transmission Module: Train of Four (TOF),
Double Burst 3,3 (DBS) and Single Twitch (ST).
In the Train of Four stimulus mode, four stimulation pulses are generated at 0.5 second intervals.
The response is measured after each stimulus and the ratio of the fourth and first response of the
TOF sequence is calculated (TOF%).
NOTE: If the first response does not exceed a certain signal level, TOF% is not calculated due to
poor accuracy.
Double burst (3,3) stimulation includes two bursts with a 750 ms interval. Both bursts consist of
three pulses separated by 20 ms intervals. The responses of both bursts are measured, and the
ratio of the second and first response is calculated (DBS%). EMG responses are measured
immediately after the first stimulus pulse of both bursts.
In Single Twitch stimulation, one stimulation pulse is generated. The response is measured after
the stimulus. In order to prevent decurarization of the stimulated area, the measurement is
automatically stopped after 5 minutes stimulation in 1 sec cycle time.
Tetanic/PTC
Tetanic/PTC (Post Tetanic Count) can measure deeper relaxation than TOF. The tetanic stimulation
is produced when Start is chosen under Tetanic/PTC. The length of stimulation is 5 seconds. The
stimulation generates pulses with a frequency of 50 Hz and with a selected pulse width and
current. After tetanic stimulation and a three second delay, Single Twitch stimulation is produced
to detect the post tetanic count (PTC). PTC describes the number of responses detected after
tetanic stimulation. If there is no response, the measurement will be stopped. If responses will not
fade away, a maximum of 20 responses will be calculated. If more can be detected, the PTC value
is displayed only as '> 20' and measurement will be stopped. If the TOF, DBS or ST measurement
cycle was on when tetanic stimulation started, the cycle will continue after the PTC. After
completing the PTC measurement during 1 minute TOF, DBS or another PTC measurement is not
possible. This is to avoid erroneous readings due to post tetanic potentiation.
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