4
Using the Module
General Considerations
Agilent InfinityLab ELSD User Manual
58
Transferring ELSD Temperature Methods
The direct transfer of ELSD operating conditions from other manufacturers’ ELS
detectors, or other designs of ELSD (e.g. Agilent G4218A ELSD) to the ELSD will
not provide equivalent performance.
As stated in
“Basic Principles of Operation”
on page 9, the operating
temperatures of the ELS detector are set according to the type of analyte and not
the mobile phase composition as with other ELS detectors. For example, when
HPLC grade water is used as the mobile phase the Agilent G4218A ELSD requires
an evaporation temperature between 35 – 40 °C, whereas the Agilent G7102A
can be operated as low as 20 – 30 °C for the equivalent solvent.
Therefore the transfer of operating conditions from other models of ELSD to the
G7102A ELSD is not valid. The only way to ensure that the detector will provide
the optimum analyte signal-to-noise is to follow the guidelines outlined
in
