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GE Xcellerex XDM 100, Operating Instructions Manual

The GE Xcellerex XDM 100 is a cutting-edge bioprocess system, revolutionizing laboratory operations. To make the most of its advanced features and functionalities, refer to the comprehensive Operating Instructions Manual. Download this invaluable resource for free at manualshive.com to unlock the full potential of your XDM 100.

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Xcellerex

™

XDM 50-1000, XDUO

100-1000 mixers

Operating Instructions

Original instructions
Translation disc enclosed

Summary of Contents for Xcellerex XDM 100

Page 1: ...Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions Original instructions Translation disc enclosed ...

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Page 3: ...rity levels 47 2 6 Recycling information 49 2 7 Declaration of Hazardous Substances DoHS 51 3 System description 52 3 1 System overview 53 3 2 Xcellerex XDM mixer system description 54 3 2 1 System hardware 55 3 2 2 Illustration of Xcellerex XDM mixer 58 3 3 Xcellerex XDUO mixer system description 59 3 3 1 System hardware 60 3 3 2 Illustration of Xcellerex XDUO mixer 63 3 4 Mixer vessel components...

Page 4: ... bag assembly 147 6 3 2 Install the disposable bag 157 6 4 Prepare and install the probes 158 6 4 1 Calibrate the pH probe 163 6 4 2 Prepare the conductivity probe 165 6 4 3 Autoclave probe sheath assembly 168 6 4 4 Insert probes into the disposable bag 182 6 5 Calibrate the monitors of Xcellerex XDM mixer 183 6 6 Prepare the pumps 187 7 Operation 188 7 1 Safety precautions 190 7 2 Operate Xceller...

Page 5: ...tions 279 10 2 SP CV and PV units and ranges 280 10 3 Xcellerex XDM and XDUO mixers minimum working volumes 281 10 4 Pump characteristics 282 10 5 Disposable bag specifications 283 10 6 Environmental requirements 284 10 7 Temperature control unit 285 10 7 1 TCU requirements 287 10 7 2 Temperature control optimization 288 10 7 3 TCU coolant specifications 289 10 8 Temperature probe calibration 294 ...

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Page 7: ...ulatory information about Xcellerex XDM and XDUO mixers In this chapter See page Section 8 1 1 About this manual 9 1 2 Important user information 11 1 3 Regulatory information 17 1 4 Abbreviations Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 1 Introduction ...

Page 8: ...your system is described in the General Specification and on the system label Examples of jacketed and non jacketed mixer types are shown below A XDM mixer 200 L jacketed B XDUO mixer 200 L non jacketed A B Typographical conventions Software items are identified in the text by bold italic text A colon separates menu levels thus File Open refers to the Open command in the File menu Hardware items a...

Page 9: ...as a stand alone instrument or as a FlexFactory component XDM and XDUO mixers are not medical devices and must not be used in any clinical procedures or for diagnostic purposes XDM and XDUO mixers are not intended for use in a potentially explosive atmosphere Prerequisites In order to operate XDM and XDUO mixers in the way it is intended The user must have a general understanding of the use of gen...

Page 10: ...n which if not avoided could result in minor or moderate injury It is important not to pro ceed until all stated conditions are met and clearly understood NOTICE NOTICE indicates instructions that must be followed to avoid damage to the product or other equipment Notes and tips A note is used to indicate information that is important for trouble free and optimal use of the product Note A tip conta...

Page 11: ...t GE Healthcare Bio Sciences AB Name and address of manufacturer Björkgatan 30 SE 751 84 Uppsala Sweden In this section See page Section 12 1 3 1 EU Directives 13 1 3 2 Eurasian Customs Union 14 1 3 3 Regulations for USA and Canada 15 1 3 4 Korean regulatory information 16 1 3 5 Other regulations and standards Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 11 1 Intro...

Page 12: ...ry Directive MD 2006 42 EC Electromagnetic Compatibility EMC Directive 2014 30 EU CE marking The CE marking and the corresponding EU Declaration of Conformity is valid for the in strument when it is used according to the Operating Instructions or user manuals and used in the same state as it was delivered from GE except for alterations described in the Operating Instructions or user manuals 12 Xce...

Page 13: ...ement See Manufacturing information Name and address of manufacturer Telephone 46 771 400 600 Telephone number of manufacturer GE Healthcare LLC Importer and or company for obtain ing information about importer GE Healthcare Life Sciences Presnenskaya nab 10C 12th floor RU 123 317 Moscow Russian Federation Telephone 1 7 495 411 9714 Fax nr 7 495 739 6932 Email LSrus ge com Xcellerex XDM 50 1000 XD...

Page 14: ...ply with the limits for a Class A digital device pursuant to part 15 of the FCC Rules These limits are designed to provide rea sonable protection against harmful interference when the equipment is operated in a commercial environment This equipmentgenerates uses and can radiateradio frequen cy energy and if not installed and used in accordance with the instruction manual may cause harmful interfer...

Page 15: ... business environment When used in a residential environment there is a concern of radio interference 주의사항 A급 기기 업무용 방송통신 기자재 이 기기는 업무용환경에서 사용할 목적으로 적합성평가를 받은 기기 로서 가정용 환경에서 사용하는 경우 전파간섭의 우려가 있습니 다 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 15 1 Introduction 1 3 Regulatory information 1 3 4 Korean regulatory information ...

Page 16: ...inery General principles for design Risk assessment and risk reduction EN ISO 12100 Safety of Machinery Electrical equipment of machines Part 1 General requirements IEC EN 60204 1 UL 508A Industrial cabinet UL 508A Electrical Equipment for Measurement Control and Laboratory Use EMC requirements Part 1 General re quirements IEC EN 61326 1 Emission according to CISPR 11 Group 1 class A Additional de...

Page 17: ... the control signal that controls the process toward the SP programmable logic controller PLC process variable PV The actual measured value of a process parameter revolutions per minute rpm Secure Digital card SD card setpoint SP The process target value defined by a user or the system that the PID controller tries to reach by adjusting the pro cess control outputs hygienic tubing connection TC te...

Page 18: ... read this chapter before using XDM or XDUO mixers and observe the safety instructions at all times during use In this chapter See page Section 19 2 1 Safety precautions 28 2 2 Labels 34 2 3 Emergency procedures 43 2 4 Xcellerex XDUO mixer interlocks 46 2 5 Security levels 47 2 6 Recycling information 49 2 7 Declaration of Hazardous Substances DoHS 18 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Ope...

Page 19: ... understand the entire contents of this chapter to become aware of the hazards involved WARNING Operate as described Do not operate the instrument in any other way than described in the instrument user documentation WARNING Qualification The customer must make sure that all installation maintenance operation and inspection is carried out by qualified personnel who are adequately trained understand...

Page 20: ...ng parts stored energy pressurization and electrical sources CAUTION Moving parts Do not place objects or fingers into valves rotating pumps fans or other moving parts This can result in damage to the equipment and or cause personal injury CAUTION Dusty and damp atmosphere Do not use the instrument in a dusty atmosphere or close to spraying water Personal protection WARNING Slipping hazard Remove ...

Page 21: ...ing unpack ing transporting or moving the system wear protective footwear preferably with steel toe cap WARNING Personal protective equipment For personal safety during the transportation installation operation and maintenance of the system always use protective glasses and other personal protective equipment appropriate for the current application The following personal protective equipment shoul...

Page 22: ...mplanted heart defib rillators from getting too close to the magnets Installation WARNING Squeezing or crushing injuries Due to the significant weight of the system great care must be taken not to cause squeezing or crushing injuries during movement WARNING Electrical installation All electrical installation must be performed by authorized personnel only WARNING Access to power switch The power sw...

Page 23: ...dents is minimized CAUTION Indoor use only The product is designed for indoor use only CAUTION Slippery surface Use caution when emptying the vessel jacket and when filling the vessel jacket with the coolant Spilling the coolant on the floor makes the floor slippery and may cause acci dents Flammable liquids and explosive environment WARNING Flammable liquids The products are not approved for hand...

Page 24: ...t Tag Out LOTO WARNING High voltage The system must always be connected to a grounded power outlet System operation WARNING Ventilation Do not block the ventilation inlets or outlets on the system WARNING Clamps on pump tubing Make sure the tubing between the pump and the disposable bag is not blocked or clamped CAUTION Pinch hazard Use caution to avoid pinching fingers between the impeller basepl...

Page 25: ...TION Hot surface Do not touch the vessel inner surface jacket inlet or outlet during high temperature runs The temperature of these items may be higher than 60 C CAUTION Pinch hazard Do not operate the pumps without the covers in place CAUTION Secure pump tubing Make sure that the pump tubing is secure and in good condition before using the pump Do not block or kink the tubing downstream of the pu...

Page 26: ... parts that are approved or supplied by GE may be used for maintaining or servicing the system CAUTION Hot surface Make sure that the instrument surface temperature is equal to room temperature before cleaning CAUTION Cleaning Always clean the equipment in a well ventilated area Never immerse any part of the equipment in liquid or spray liquid on the equipment Always make sure that the equipment i...

Page 27: ...fore performing any service work on the system make sure that the system has been properly decon taminated Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 27 2 Safety instructions 2 1 Safety precautions ...

Page 28: ... the product Labels on the system A system label 1 with regulatory information is present on the system Your system may also have an ASME label 2 The following illustration shows the location of the labels 1 2 28 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 2 Labels ...

Page 29: ...o Sciences AB 751 84 Uppsala Made in Sweden MSIP REM 2GE 0XXXX The system label information is explained below Meaning Label text Jacketed or non jacketed Vessel Type Part number of the system Code number Serial number of the system System number The year and month the system was built Manufacturing Year Month Electrical power requirements V Supply Voltage Maximum current consumption A System FLA ...

Page 30: ...gnetic compliance EMC in Australia and New Zealand This symbol indicatesthat the product contains hazardous materials in excess of the limits established by the Chinese standard GB T 26572 Requirements of concentration limits for certain hazardous substances in electrical and electronic products The system complies with applicable European directives Eurasian Conformity mark the single conformity ...

Page 31: ... 10 5 L 1 4307 304L 29241073 N B The ASME label information is explained below Meaning Label text symbol Symbol of the National Board of Boiler and Pressure Vessel Inspectors N B Registration number identifying the ASME BPVI inspection stamp N B American Society of Mechanical Engineers Boiler and Pressure Vessels Code stamp symbol The welded W productis manufactured accordingto ASME BPVC Division ...

Page 32: ...signed for FLUID Definition of fluid 1 dangerous 2 non dangerous accord ing to European legislation FLUID GROUP Vessel classification according to European legislation PED 2014 68 UE The design code used to produce the vessel CODE The pressure vessel volume VOLUME The pressure vessel material ASME specification MATERIAL Pressure vessel article number MODEL 32 Xcellerex XDM 50 1000 XDUO 100 1000 mi...

Page 33: ...voltage can cause se vere injury or death Turn off power and Lock Out Tag Out LOTO before service Warning Hot surface Do not touch the vessel surface and areas around the vessel jacket inlet SUPPLY and outlet RETURN during high temper ature runs The temperature of the vessel surface may be higher than 60 C Do not perform any maintenance work until the vessel walls have cooled down Warning and enta...

Page 34: ...failure and the procedure for restarting the mixers In this section See page Section 35 2 3 1 Emergency procedures Xcellerex XDM mixer 37 2 3 2 Emergency procedures Xcellerex XDUO mixer 42 2 3 3 Power or communication failure 34 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 3 Emergency procedures ...

Page 35: ...r is removed from the I O Cabinet If required disconnect the power cord from the mains power supply Restart XDM mixer Follow the instructions below to restart XDM mixer after an emergency shutdown or a power failure Action Step Make sure that the condition that caused the emergency shutdown is cor rected 1 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 35 2 Safety in...

Page 36: ...mains power supply 2 Turn the system power switch to I ON position 3 36 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 3 Emergency procedures 2 3 1 Emergency procedures Xcellerex XDM mixer ...

Page 37: ...e forced into Manual mode and remain in a safe state Agitator motor is turned off The TCU is turned off E STOP is displayed on every local control software screen Data logging continues if enabled Press the EMERGENCY STOP button Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 37 2 Safety instructions 2 3 Emergency procedures 2 3 2 Emergency procedures Xcellerex XDUO m...

Page 38: ...structions below to restart XDUO mixer after an emergency shutdown or a power failure Action Step Make sure that the condition that caused the emergency shutdown is cor rected 1 Connect the power cord to the mains power supply 2 38 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 3 Emergency procedures 2 3 2 Emergency procedures Xcellerex XDUO m...

Page 39: ...MERGENCY STOP button by turning it clockwise 4 Result The EMERGENCY STOP button pops out Tap Login on the top toolbar of the home screen 5 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 39 2 Safety instructions 2 3 Emergency procedures 2 3 2 Emergency procedures Xcellerex XDUO mixer ...

Page 40: ... the text boxes Tap OK 6 Tap RESET on the local control software screen 7 40 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 3 Emergency procedures 2 3 2 Emergency procedures Xcellerex XDUO mixer ...

Page 41: ...ed system If a batch was running prior to when the EMERGENCY STOP was pushed the system is set in the Held state If a batch was not running XDUO mixer remains in a safe state If a batch was running prior to emergency stop the user must verify the status of all PID control loops and setpoints before restarting the batch after power restoration Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating In...

Page 42: ...as described in Section 7 3 1 Start up the system on page 199 Communication failure with FlexFactory Result Event Communication between XDUO mixer and FlexFactory fails The mixer goes to local control mode Agitation pH control and temperature control stop Communication recovery pH control and temperature control loops stay in a safe state The agitator stays turned off XDUO mixer stays disconnected...

Page 43: ...ow the interlock limit for 30 seconds The vessel weight is more than the Max Weight interlock limit Interlocks stop the pumps pH control The vessel temperature control goes into Manual mode The pumps pH control and the temperature control start again in the previously active mode 30 seconds after the agitator is turned on The agitator is shut off while tem perature or pH control is running 1 1 The...

Page 44: ...00 1000 L delay time If the interlocked PID control loop was in the Auto mode before the interlock the control restarts automatically in the Auto mode when the interlock condition is corrected and the delay time has passed Interlock status The interlocks are shown on the local control software home screen 44 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety ins...

Page 45: ...terlock is active The interlock icon and name are shown in orange The interlock is not active The interlock icon and name are shown in gray Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 45 2 Safety instructions 2 4 Xcellerex XDUO mixer interlocks ...

Page 46: ...rity level System functions Administrator Supervisor Operator Monitor alarms Monitor and control pH Monitor and control the temperature Monitor the vessel weight Operate the agitators Monitor trends Configure alarms Access Service screen Access Setup screen Access User Adminstration screen add and remove users 46 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safet...

Page 47: ...to national and local environmental regulations Recycling of hazardous substances XDM and XDUO mixers contain hazardous substances Detailed information is available from your GE representative Disposal of electrical components Waste electrical and electronic equipment must not be disposed of as unsorted municipal waste and must be collected separately Please contact an authorized representative of...

Page 48: ...supplies trans mitters pumps probes sensors etc from the I O Cabinet and the mixer vessel 2 Decontaminate the probes and sensors that have come into contact with the process fluid Dispose of the fluid by following the disposal of hazard materials according to the facility the unit is located in 3 Dispose of electronic components as specified by local guidelines depending on material used in the co...

Page 49: ...e Period EFUP which indicates the period during which the hazardous substances contained in electrical and elec tronic products will not leak or mutate under normal operating conditions so that the use of such electrical and electronic products will not result in any severe environmen tal pollution any bodily injury or damage to any assets The unit of the period is Year In order to maintain the de...

Page 50: ...材料中的含量超出 GB T 26572规定的限量要 求 此表所列数据为发布时所能获得的最佳信息 0 Indicates that this hazardous substance contained in all of the homogeneous materials for this part is below the limit requirement in GB T 26572 X Indicates that this hazardous substance contained in at least one of the homogeneous materials used for this part is above the limit requirement in GB T 26572 Data listed in the table represents best inf...

Page 51: ... overview 53 3 2 Xcellerex XDM mixer system description 58 3 3 Xcellerex XDUO mixer system description 63 3 4 Mixer vessel components 71 3 5 Safety hardware 72 3 6 Mixer automation and control 74 3 7 Temperature control unit 75 3 8 Disposable components Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 51 3 System description ...

Page 52: ...ingredients are added through a port at the top of the disposable bag using a hopper or a powder bag Mixing of the disposable bag contents is done by an agitator that is magnetically coupled to an impeller installed inside the bag The agitation is provided by a servo drive and a motor The contents of the disposable bag are monitored during the mixing process using probes that are inserted into the...

Page 53: ... general overview of XDM mixer In this section See page Section 54 3 2 1 System hardware 55 3 2 2 Illustration of Xcellerex XDM mixer Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 53 3 System description 3 2 Xcellerex XDM mixer system description ...

Page 54: ...on the purchased options The following monitoring functions are available Conductivity pH Temperature Weight The jacketed mixer vessel allows the temperature control of the mixer contents An ex ternal temperature control unit TCU is used for temperature regulation The TCU is an optional component 54 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 3 System description ...

Page 55: ... vary according to the selected optional features Front view 4 3 2 1 10 9 8 7 6 5 Function Part Weight monitor display 1 Temperature monitor display 2 pH conductivity transmitter display 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 55 3 System description 3 2 Xcellerex XDM mixer system description 3 2 2 Illustration of Xcellerex XDM mixer ...

Page 56: ...tube rack 9 Probe window and probe support bar 10 Rear view 11 12 13 14 15 16 17 18 19 18 Function Part Coolant outlet to TCU 11 Mixer vessel 12 56 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 3 System description 3 2 Xcellerex XDM mixer system description 3 2 2 Illustration of Xcellerex XDM mixer ...

Page 57: ...urst disc 15 Agitator motor 16 Load cell and jacking bolt 4 17 Ventilation hood 2 18 Power switch 19 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 57 3 System description 3 2 Xcellerex XDM mixer system description 3 2 2 Illustration of Xcellerex XDM mixer ...

Page 58: ...general overview of XDUO mixer In this section See page Section 59 3 3 1 System hardware 60 3 3 2 Illustration of Xcellerex XDUO mixer 58 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 3 System description 3 3 Xcellerex XDUO mixer system description ...

Page 59: ... thepurchasedoptions Thefollowingmonitoring functions are available Conductivity pH Temperature Weight The following control functions are available pH Temperature jacketed mixer only An external temperature control unit TCU is used for temperature regulation The TCU is an optional component Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 59 3 System description 3 3 X...

Page 60: ...ation of each mixer may vary according to the selected optional features Front view 2 3 4 5 6 7 8 9 10 11 12 13 1 Function Part I O Cabinet 1 Base pump 2 Acid pump 3 60 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 3 System description 3 3 Xcellerex XDUO mixer system description 3 3 2 Illustration of Xcellerex XDUO mixer ...

Page 61: ...e touchscreen 7 Acrylic lids 8 Opening for liquid addition lines 9 Push bar 10 Side access door 11 Test tube rack 12 Probe window and probe support bar 13 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 61 3 System description 3 3 Xcellerex XDUO mixer system description 3 3 2 Illustration of Xcellerex XDUO mixer ...

Page 62: ... 4 17 Vessel jacket safety outlet from burst disc 18 Agitator motor 19 Load cell and jacking bolt 4 20 Ventilation hood 2 21 Power switch 22 62 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 3 System description 3 3 Xcellerex XDUO mixer system description 3 3 2 Illustration of Xcellerex XDUO mixer ...

Page 63: ... of the components of the mixer vessel In this section See page Section 64 3 4 1 Mixer vessel 66 3 4 2 Agitator 68 3 4 3 Load cells 70 3 4 4 Pumps Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 63 3 System description 3 4 Mixer vessel components ...

Page 64: ... tubing and for connecting a hopper or a powder bag See Illustration of mixer lid on page 65 A probe window is used to insert probes into the disposable bag for monitoring the contents A combined probe support and test tube rack is attached to the probe window The mixer vessel bottom has two openings a drain opening in the corner of the vessel and the agitator drive head in the center of the vesse...

Page 65: ... 1 B Function Part Opening for liquid addition lines 1 Lid part 2 Lid handle 4 3 Powder addition port1 4 1 Powder addition port is designed for connecting hopper or powder bag to the disposable bag Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 65 3 System description 3 4 Mixer vessel components 3 4 1 Mixer vessel ...

Page 66: ... connected Function of the agitator There are no openings in the disposable bag wall for agitation access The impeller baseplate is welded into the bottom of the disposable bag The impeller baseplate is connected to the agitator motor via magnetic coupling The magnetic field holds the impeller baseplate to the agitator drive head and transfers the rotational energy from the agitator motor to the i...

Page 67: ...en 10 to 200 rpm A frequency inverter is used to change the motor speed Agitation direction The agitator can rotate clockwise or counterclockwise Description Agitator direction Fluid rotates downwards Clockwise Fluid rotates upwards Counterclockwise Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 67 3 System description 3 4 Mixer vessel components 3 4 2 Agitator ...

Page 68: ...ixer vessel up lock it and take the load off from the load cells thereby preventing the damage to the load cells The jacking bolts must be disengaged during mixer operation so that the vessel weight can be monitored The accuracy of the mixer weight measurement should be verified when the mixer has been moved a short distance for example during cleaning Load cells are an optional component 68 Xcell...

Page 69: ...Top nut 2 Lifts the vessel off the load cell Bottom nut 3 Takes the load off from the load cell Jacking bolt 4 Locks the bolt inserted into the mixer frame Bolt locking nut 5 Measures the vessel weight Load cell 6 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 69 3 System description 3 4 Mixer vessel components 3 4 3 Load cells ...

Page 70: ...cluded in the configuration of XDUO mixers The pumps operate at variable speed Changing the CV between 0 and 100 increases the speed linearly over the range For the characteristics of the pumps see Section 10 4 Pump characteristics on page281 Illustration of a model 313 pump 1 2 1 Description Part Adjustment wheel for gripping elements 1 Roller 2 70 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Opera...

Page 71: ... 2 2 Labels on page 28 for detailed information Burst disc Jacketed XDM and XDUO mixers are equipped with a burst disc which is designed to rupture when the vessel jacket pressure approaches the accepted test pressure This prevents catastrophic failure of the vessel jacket Any leaking or dripping from the vessel jacket should immediately be reported to your GE representative to get support Interlo...

Page 72: ...peed drive for controlling the agitator motor speed and direction The following functions are available Start and stop the agitator motor Change agitation speed Change agitation direction Xcellerex XDUO mixer control The XDUO mixer is operated using the local control software The local control panel contains a programmable logic controller PLC for process control The communication with PLC is done...

Page 73: ...l displays the cur rent process variables The modification of these variables comes into effect when the mixer is run in local mode The process variables can be modified using the local control panel Full time trending data is available 5 min trending data is available Historization is available from the FlexFactory system Historization is available via local data logging and audit trail Authoriza...

Page 74: ...s the TCU with the mixer I O Cabinet Consult the manufacturer s manuals for more information about the TCU Models of temperature control units Two types of temperature control units can be used with the jacketed mixers Heating only or Heating and cooling Heating and cooling TCU Heating TCU The facility does not provide an in house cooling system The cooling is provided by the facility where the sy...

Page 75: ... disposable components that are needed for a mixing process In this section See page Section 76 3 8 1 Disposable bag assembly 82 3 8 2 Probe sheath assembly Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 75 3 System description 3 8 Disposable components ...

Page 76: ...tent adjustment two probe ports and a thermowell The Plus bag assembly has one liquid addition line for acid and base solutions and the Plus Flex bag has two liquid addition lines Connection to the liquid entry points is done via bulkhead type seals All addition lines and the drain line the probe ports the thermowell and the impeller baseplate on the bag are designed to align with the openings and...

Page 77: ...ws the top of the Plus Flex bag 1 2 7 6 5 4 3 The following illustration shows the underside of the Plus Flex bag 9 8 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 77 3 System description 3 8 Disposable components 3 8 1 Disposable bag assembly ...

Page 78: ... line with clamp plugged 9 1 This addition line can be used for final adjustment of liquid volume in the disposable bag 2 The line is designated for addition of acid or base solutions The following illustration shows a detailed view of the probe ports of the Plus Flex and Plus bag 1 2 3 Function Part Probe ports female Kleenpak connector 1 Temperature probe port 2 Sample line i d with clamp Luer l...

Page 79: ...he top of the Plus bag 1 2 3 4 5 6 7 8 The following illustration shows the underside of the Plus bag 1 3 4 5 6 7 8 9 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 79 3 System description 3 8 Disposable components 3 8 1 Disposable bag assembly ...

Page 80: ...ller baseplate with impeller assembly 9 1 This addition line can be used for final adjustment of liquid volume in the disposable bag 2 The line is designated for addition of acid and base solutions See Illustrations of the Plus Flex bag assembly on page 77 for the detailed view of the probe ports Illustrations of the Basic bag assembly The following illustration shows the top of the Basic bag 1 2 ...

Page 81: ...p plugged 5 Storage of the disposable bag assembly The recommended storage temperature for the disposable bag assembly is between 10 C and 34 C Information about the storage temperature is shown on the bag label Operating temperature The disposable bag assembly is rated for temperatures between 5 C and 65 C Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 81 3 System d...

Page 82: ...he ACD is used to connect the probe sheath assembly to the disposable bag The probe sheath is compatible with the following 12 225 mm probes Conductivity probe pH probe The probes are connected to the probe sheath using a PG 13 5 threaded connector The probe sheath assembly must be autoclaved before connecting it to a probe port Illustration of a probe The following illustration shows a pH probe 1...

Page 83: ...le end 1 Aseptic membrane 2 Anti actuation ring 3 Bellows 4 End plug 5 Illustration of the probe sheath assembly The following illustration shows a probe sheath with the inserted probe Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 83 3 System description 3 8 Disposable components 3 8 2 Probe sheath assembly ...

Page 84: ...ftware The parts used in daily op erations are described in Section 7 3 Operate Xcellerex XDUO mixer on page 198 In this chapter See page Section 85 4 1 General description 90 4 2 Adjustment and control screens 93 4 3 Alarm screens 98 4 4 Detail screens 113 4 5 Trend screens 84 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 4 User interface ...

Page 85: ...e detail screen for the corresponding process variable The home screen also shows the current values of the relevant process variables Home screen The home screen is the default screen at XDUO mixer startup The contents of the home screen depend on the installed options An example of the home screen is shown in the following illustration 1 3 4 7 8 9 10 11 12 13 5 6 2 Xcellerex XDM 50 1000 XDUO 100...

Page 86: ...Restart XDUO mixer on page 38 RESET 6 Nothing is shown during normal operation Shows if data logging is active The status is shown in green Logging Active or gray Logging Inactive See Start and stop data logging on page 205 Logging Inactive 7 Displays the temperature of both temperature sen sors C The currently selected temperature sensor is shown in black The active control mode Manual or Auto is...

Page 87: ...Process variable display The numeric fields on the process variable display show the current values of process variables Tapping the display opens the detail screen for the relevant process variable The detail screen can also be opened by clicking a button on the left hand side of the screens see the illustration of the home screen in Home screen on page 85 for more information The following illus...

Page 88: ...mode In Auto mode the user defines a setpoint SP The local control software specifies the controlled variable CV via a PID control loop In Manual mode the user defines a controlled variable CV Batch Timer Batch Timer is a general purpose timer It is a manually operated function and works as an ordinary stopwatch Batch Timer is shown on the following screens Agitator Detail screen All Trend screens...

Page 89: ...g a text box for numeric entry opens a numeric keypad The following illustration shows the numeric keypad Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 89 4 User interface 4 1 General description ...

Page 90: ...L PANEL 1 Button to open the Transmitter Offsets screen Transmitter Offsets screen on page 111 OFFSETS 2 Button to start or stop data logging The cur rent logging status is shown on the top tool bar Logging Inactive Logging Active See Start and stop data logging on page 205 START LOGGING STOP LOGGING 3 Button to open Time Management screen See Time Management screen on page 92 SET CLOCK 4 Button t...

Page 91: ...the local control software PLC HMI SW version 10 Instrumentcontrol option FlexFactory control or local control FF Control Option 11 PROFIBUS node number applicable if the system is controlled by FlexFactory Profibus Node 12 Instrument number in FlexFactory for FlexFactory connected systems Remote HMI Mixer 13 Instrument number in customer equipment inventory Customer Equip 14 Instrument serial num...

Page 92: ...me Management screen 1 2 Description Part Text boxes for date and time information 1 Button to set the date and time 2 When the date and time are changed it may take a few minutes until the new time is shown on the top toolbar 92 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 4 User interface 4 2 Adjustment and control screens ...

Page 93: ...e alarm overview screen and alarm configuration screens In this section See page Section 94 4 3 1 Alarm overview screen 95 4 3 2 Alarm configuration screens Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 93 4 User interface 4 3 Alarm screens ...

Page 94: ...ht High High Alarm The alarm icon is always gray when the alarm overview screen is open even when active alarms exist on the system Illustrationofthealarm overview screen The following illustration shows an example of the alarm overview screen The following information is shown for each alarm Time Date Tag name of the unit where the alarm occurred Short description of the alarm 94 Xcellerex XDM 50...

Page 95: ...High Alarm High Alarm Low Alarm Low Low Alarm The alarm levels are set by the user according to process specific requirements Only Supervisor and Administrator can set the alarm limits The user opens the alarm configuration screens by tapping ALARM CONFIG on Agitator Detail Conductivity Detail pH Detail Temperature Detail or Weight Detail screens See Section 7 3 7 Set alarm limits on page227 for i...

Page 96: ...nnot be changed by the user See Section 7 3 7 Set alarm limits on page227 for instructions how to set the accessible alarm limits See Section 2 4 Xcellerex XDUO mixer interlocks on page 43 for more infor mation about interlock limits Alarm functionality When an alarm is issued a warning icon is displayed The system continues to run 96 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructio...

Page 97: ...all four alarm setpoints SP for each functionality If duplicate probes are installed on the system pH or temperature probes the PLC uses data from the currently selected probe for the alarm Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 97 4 User interface 4 3 Alarm screens 4 3 2 Alarm configuration screens ...

Page 98: ...nductivity temperature and weight In this section See page Section 99 4 4 1 Overview 100 4 4 2 Agitator screen 102 4 4 3 Conductivity screen 103 4 4 4 pH screens 107 4 4 5 Temperature screens 112 4 4 6 Weight screen 98 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 4 User interface 4 4 Detail screens ...

Page 99: ...s the user back to the previous screen Tapping ALARM CONFIG opens the alarm configurationscreen for the parameter See Section 4 3 2 Alarm configuration screens on page 95 Tapping TREND opens the Trend screen for the parameter See Section 4 5 Trend screens on page 113 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 99 4 User interface 4 4 Detail screens 4 4 1 Overview ...

Page 100: ...ned by tapping AGITATION on the navigation toolbar The following illustration shows an example of the Agitator Detail screen 1 2 3 4 5 6 7 8 100 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 4 User interface 4 4 Detail screens 4 4 2 Agitator screen ...

Page 101: ...tate is shown as Stopped the agitator motor drive is defective 3 Agitator state indicator Running or Stopped 4 Batch Timer display 5 STOP button 6 START button 7 Toggle button to change the agitator direction to CW or CCW See Agitation direction on page 67 for more information 8 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 101 4 User interface 4 4 Detail screens 4 ...

Page 102: ...e navigation toolbar The following illustration shows an example of the Conductivity Detail screen The screen shows the process variable PV value for the conductivity probe 102 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 4 User interface 4 4 Detail screens 4 4 3 Conductivity screen ...

Page 103: ...rrent pH value PV displays for probes 1 and 2 The currently selected probe is shown in black AIT_121 pH PV AIT_122 pH PV 2 Two values are shown if XDUO mixer has dual pH monitoring pH controlled variable CV display Note In Auto mode this value is calculated by the PLC In Manual mode PHC_125 Manual CV is used as PHC_125 pH CV PHC_125 pH CV 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Inst...

Page 104: ...o open the Prime Pumps screen See Prime the pump on page 212 PUMPS SETUP 7 Button to open the pH PID Settings screen See pH PID Settings screen on page 105 PID SETTINGS 8 Pump speed displays controlled variable CV for the acid pump and the base pump Shown in of total pump speed range P 201 SC_201 Acid PID CV P 202 SC_202 Base PID CV 9 1 Only shown in Manual mode 104 Xcellerex XDM 50 1000 XDUO 100 ...

Page 105: ...process variable PV dis play for the selected probe PV 2 pH controlled variable CV display PID con troller output CV 3 Note In Auto mode this value is calculated by the PLC In Manual mode Manual CV is used as CV User defined CV controlled variable value for pH PID controller output Manual CV1 4 Note In Manual mode the Manual CV value is used as CV Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operati...

Page 106: ...portional 7 I Term integral D Term derivative Pump speed displays controlled variable CV for the acid pump and the base pump Shown in of total pump speed range SC_201 Acid PID CV SC_202 Base PID CV 8 1 Only shown in Manual mode Factory default values for the parameters on the pH PID Settings screen are suitable for most applications 106 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instruct...

Page 107: ...s Text box for input TC_163 Temperature SP 1 Current temperature process variable PV displays for temperature probe sensors 1 and 2 The currently selected sensor is shown in black TE_161 Temperature PV TE_162 Temperature PV 2 Temperature PID controller output controlled variable CV display shown in of config uredTCU remotesetpointtemperature range Note In Auto mode this value is calculated by the ...

Page 108: ... open the Transmitter Offsets screen See Transmitter Offsets screen on page 111 OFFSETS 5 Button to open the Temperature PID screen See Temperature PID screen on page 109 PID SETTINGS 6 Toggle button to select the temperature sensor TE_161 TE_162 7 Toggle button to select the control mode Auto Manual 8 1 Only shown in Manual mode 108 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instruction...

Page 109: ...re process variable PV display for currently selected temperature sensor PV 2 Note The sensor is selected on the Temperature Detail screen Temperature PID controller output controlled variable CV display shown in of config ured TCU temperature range CV 3 Current temperature process variable PV displays for temperature probe sensors 1 and 2 The currently selected sensor is shown in black TE_161 PV ...

Page 110: ...ording to the actual operating range of the TCU CV HiLimit CV LoLimit 6 User defined limits for the input range of temperature setpoint SP of disposable bag contents Note The SP limits specify the allowed temperature range for the contents of the disposable bag SP HiLimit SP LoLimit 7 1 For example the remote setpoint range of the TCU is 10 C to 90 C The CV 0 sets the TCU remote setpoint to 10 C T...

Page 111: ...creen The currently selected sensor is shown in black The following illustration shows an example of the Transmitter Offsets screen 1 2 3 Function Description Part Displays of the actual process variable PV value Xmitter 1 Parameter offset values positive or negative text boxes for input Offset 2 Displays of process variable PV values after offset ad justment PV 3 Xcellerex XDM 50 1000 XDUO 100 10...

Page 112: ... the Weight Detail screen The screen shows the process variable PV value for the mixer vessel weight Tapping Tare lets the user to tare the mixer vessel weight See Section 7 3 6 Manage mixer weight on page 225 for more information 112 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 4 User interface 4 4 Detail screens 4 4 6 Weight screen ...

Page 113: ...or the setpoint SP and the current process variable PV The Conductivity Trend and Weight Trend screens show only the graph for the current process variable PV Trending is displayed for the last 5 minutes in the local control software The information is available for viewing only For a FlexFactory connected system trending is available on FlexFactory inter face for the whole elapsed time since conn...

Page 114: ...ot applicable Weight XDUO 1001 250 kg Not applicable Not applicable Weight XDUO 2001 625 kg Not applicable Not applicable Weight XDUO 5001 1250 kg Not applicable Not applicable Weight XDUO10001 1 Negative PV values may be shown in the graphs The lower limit has not been verified Illustration of a Trend screen The following illustration shows an example of a Trend screen If two probes are available...

Page 115: ...ss variable PV axis and measurement unit 1 Graph area 2 Controlled variable CV axis and measurement unit 3 Legend 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 115 4 User interface 4 5 Trend screens ...

Page 116: ... not covered in this manual must not be installed by the customer For unpacking instructions see separate Xcellerex XDM and XDUO mixers Unpacking Instructions manual In this chapter See page Section 117 5 1 Safety precautions 119 5 2 Site requirements 121 5 3 Installation of the mixer 122 5 4 Connect temperature control unit 116 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 292...

Page 117: ...e impeller assembly of the disposable bags OBSERVE and follow instructions for installation operation and maintenance of XDM and XDUO mixer KEEP a safe distance of 25 cm or more from the magnets to avoid exposure to magnetic field greater than 0 5 mT 5 G WARN people who wear pacemakers or implanted heart defib rillators from getting too close to the magnets WARNING Access to power switch The power...

Page 118: ...rocedure for Lock Out Tag Out LOTO WARNING Keep jacking bolts Do not remove jacking bolts from the installed system CAUTION Tripping hazard Make sure that all tubing hoses and cables are placed so that the risk for tripping accidents is minimized CAUTION Indoor use only The product is designed for indoor use only 118 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 5 I...

Page 119: ...ent working conditions during the use sufficient space should be provided on all sides of the instrument when installed at the intended production location Environmental conditions The following general requirements must be fulfilled The room must have exhaust ventilation The instrument should not be exposed to corrosive gases The instrument should not be exposed to sources of heat such as direct ...

Page 120: ...tch must be set in the O OFF position and the power cord must be disconnected Computer An external computer is not required Temperature regulation For temperature control of the jacketed XDM mixer or XDUO mixer a temperature control unit TCU is required See the manufacturer s manual for specified environmental condi tions and electrical power requirements for the TCU NOTICE The temperature control...

Page 121: ...ersonnel only WARNING High voltage The system must always be connected to a grounded power outlet The customer must install an electrical plug on the main power cord of XDM and XDUO mixers The plug must comply with local regulations Configure the local control software It is recommended to configure the Administrator account when the instrument hard ware has been installed See Manage the Administr...

Page 122: ...cribed in the user documentation If you do you may be exposed to hazards that can lead to personal injury and you may cause damage to the equipment Connect TCU Follow the instructions below to connect the TCU to your XDM or XDUO mixer Action Step Connect the TCU to the power supply Use an applicable cable 1 Connect the communication cable to the applicable port on the TCU 2 122 Xcellerex XDM 50 10...

Page 123: ...y surface Use caution when emptying the vessel jacket and when filling the vessel jacket with the coolant Spilling the coolant on the floor makes the floor slippery and may cause acci dents For information on the vessel jacket volume of XDM and XDUO mixers see Section 10 1 System specifications on page 274 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 123 5 Installa...

Page 124: ...et with the coolant Action Step Make sure that the vent valve and the drain valve of the mixer vessel jacket are closed 1 124 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 5 Installation 5 4 Connect temperature control unit ...

Page 125: ...lant inlet SUPPLY of the mixer vessel 2 Connect the TCU inlet tubing to the coolant outlet RETURN of the mixer vessel 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 125 5 Installation 5 4 Connect temperature control unit ...

Page 126: ...sh both parts of the connector together c Release the locking ring Result The locking ring moves back and emits a click The connector is locked Remove the reservoir cap on the TCU and and fill the reservoir with coolant 5 Reinstall the cap and turn on the TCU 6 126 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 5 Installation 5 4 Connect temperature control unit ...

Page 127: ... emptying the vessel jacket and when filling the vessel jacket with the coolant Spilling the coolant on the floor makes the floor slippery and may cause acci dents Follow the instructions below to empty the vessel jacket Action Step Turn off the TCU 1 NOTICE Do not drain the jacket immediately after use due to coolant high temperature Disconnect the coolant inlet and outlet tubing from the TCU 2 X...

Page 128: ...he content of the tubing into the vessel jacket 7 Prepare the tubing for draining the vessel jacket bottom 8 a Attach a Snap tite connector to the tubing b Put the end of the drain tubing into the collection container c Connect the Snap tite connector of the drain tubing to the coolant inlet tubing connected to SUPPLY See Fill the vessel jacket on page 123 for more information about Snap tite conn...

Page 129: ...apter See page Section 130 6 1 Safety precautions 132 6 2 Stabilize the mixer vessel 139 6 3 Prepare the disposable bag 157 6 4 Prepare and install the probes 182 6 5 Calibrate the monitors of Xcellerex XDM mixer 183 6 6 Prepare the pumps Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 129 6 Preparation ...

Page 130: ... DEATH or SERIOUS INJURY Magnets are located on the bottom of XDM and XDUO mixer and in the impeller assembly of the disposable bags OBSERVE and follow instructions for installation operation and maintenance of XDM and XDUO mixer KEEP a safe distance of 25 cm or more from the magnets to avoid exposure to magnetic field greater than 0 5 mT 5 G WARN people who wear pacemakers or implanted heart defi...

Page 131: ...s engage the jacking bolts before moving the instrument This prevents damage to the load cells Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 131 6 Preparation 6 1 Safety precautions ...

Page 132: ...hat XDM and XDUO mixers are in a stable position during preparation and operation In this section See page Section 133 6 2 1 Use jacking bolts 138 6 2 2 Lock and unlock casters 132 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 2 Stabilize the mixer vessel ...

Page 133: ...s The jacking bolt threads are undamaged The jacking bolts are fully engaged in the mixer vessel frame The top and bottom nuts turn freely using fingers alone Turn up the bottom nut 1 with your fingers to the vessel support plate 2 Then turn the nut one half turn with a wrench so that the vessel weight is lifted off from the load cell 2 1 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Inst...

Page 134: ... nut and tighten it slightly with a wrench 4 Repeat steps 2 to 4 for all four jacking bolts installed on the mixer 5 Result The jacking bolts are engaged and the load cells are protected from possible damage caused by movement 134 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 2 Stabilize the mixer vessel 6 2 1 Use jacking bolts ...

Page 135: ...to disengage the jacking bolts Action Step Turn up the securing nut 1 on the bolt by a few turns using a wrench 1 1 2 Turn up the top nut 2 on the bolt by 1 to 2 turns using the wrench 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 135 6 Preparation 6 2 Stabilize the mixer vessel 6 2 1 Use jacking bolts ...

Page 136: ... nut must be at least 2 to 3 mm 3 Repeat steps 1 to 3 for all four jacking bolts installed on the mixer 4 Result The jacking bolts are disengaged The load cells support the mixer vessel 136 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 2 Stabilize the mixer vessel 6 2 1 Use jacking bolts ...

Page 137: ...tions Depending on site require ments a functional check or load cell calibration might be required before operating the mixer Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 137 6 Preparation 6 2 Stabilize the mixer vessel 6 2 1 Use jacking bolts ...

Page 138: ... by pressing down the tab on each brake Unlock the casters Before moving the instrument unlock each caster by pushing hard the top tab towards the instrument frame 138 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 2 Stabilize the mixer vessel 6 2 2 Lock and unlock casters ...

Page 139: ... assembly The in structions are applicable for both XDM and XDUO mixers In this section See page Section 140 6 3 1 Unpack the disposable bag assembly 147 6 3 2 Install the disposable bag Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 139 6 Preparation 6 3 Prepare the disposable bag ...

Page 140: ... bag size 60 60 cm 25 25 in 100 L 70 70 cm 30 30 in 200 L 90 90 cm 40 40 in 500 L 110 110 cm 45 45 in 1000 L To unpack a 200 L or larger bag assembly you need an assistant to help you Start unpacking the bag assembly NOTICE Use only your fingers to remove protective wrappings and zip ties from the disposable bag assembly and from the tubing Scissors and cable tie cutters might puncture the bag ass...

Page 141: ...ssembly and place the bag on the inspection table 2 Carefully open the outer protective bag and take out the bag assembly 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 141 6 Preparation 6 3 Prepare the disposable bag 6 3 1 Unpack the disposable bag assembly ...

Page 142: ...e the wrap from the tubing ports tubing connectors and filters These items need protection during bag installation The wrap can be removed after the bag has been installed 142 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 3 Prepare the disposable bag 6 3 1 Unpack the disposable bag assembly ...

Page 143: ...Made in USA GE Healthcare Bio Sciences Corp 14 Walkup Drive Westborough MA 01581 Patents www pall com patents DESCRIPTION 1 2 Note The label above is an example Actual data printed on the label is specific for each bag Verify that the gamma irradiation dot 2 on the bag label is red indicating successful sterilization 7 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 1...

Page 144: ... remove the protective bags from the probe ports tubing connectors and filters Unprotected connectors may be damaged or contaminated during the installation of the disposable bag Remove the protection after the installation 144 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 3 Prepare the disposable bag 6 3 1 Unpack the disposable bag assembly ...

Page 145: ...ies that hold the lines together Loose lines can be damaged during bag installation Remove the bubble wrap from the drain line 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 145 6 Preparation 6 3 Prepare the disposable bag 6 3 1 Unpack the disposable bag assembly ...

Page 146: ... failed bag integrity 5 Verify that the clamps on all lines are closed 6 Carefully turn over the bag assembly and remove the bubble wrap and foam from the impeller baseplate 7 Remove any additional wrapping at the top of the disposable bag 8 Result The disposable bag assembly is ready to be installed into the vessel Dispose of the box according to local procedures 9 146 Xcellerex XDM 50 1000 XDUO ...

Page 147: ...disposable bag installation wipe clean and dry the vessel wall if necessary Water on the vessel wall might be mistaken for bag leakage Follow the instructions below to start the installation of the bag assembly Action Step Remove the lid parts from the mixer 1 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 147 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Instal...

Page 148: ...low the instruc tions below 2 a Hold the door handle tightly b Turn the door counterclockwise c Remove the door 148 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Install the disposable bag ...

Page 149: ...tom center 1 Drain opening at the bottom corner of the vessel 2 Probe window at the side corner of the vessel 3 Side access opening if applicable 1 2 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 149 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Install the disposable bag ...

Page 150: ... the vessel 3 If you are installing a Plus or Plus Flex bag assembly make sure that the probe connectors 1 face the probe port 2 1 2 150 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Install the disposable bag ...

Page 151: ... pull the line through the opening Tip The drain line is more easily reached from the underside of the vessel 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 151 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Install the disposable bag ...

Page 152: ...owly lower the impeller baseplate onto the agitator drive head 6 Result The impeller baseplate connects magnetically to the drive head A click is heard when the contact is made Note Verify visually that the impeller assembly is in contact with the agitator drive head Re install the side access door 7 152 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 ...

Page 153: ... does not function correctly If the agitator emits a loud clicking noise during operation the impeller baseplate is decoupled from the magnetic drive head To correct the impeller position follow the instructions below Action Step Lift the bag upwards and disengage the impeller baseplate from the agitator motor 1 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 153 6 Pr...

Page 154: ...llation on page 147 3 Complete bag installation If you are installing a Plus or Plus Flex bag assembly insert the pH and conductivity probes into the disposable bag See Section 6 4 Prepare and install the probes on page157 for detailed instructions Follow the instructions below to finish the installation of the disposable bag assembly 154 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instru...

Page 155: ...rect position of tubing helps the adjustment of the disposable bag Install the hopper if applicable A Disconnect the TC clamp from the disposable bag powder addition port 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 155 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Install the disposable bag ...

Page 156: ...e powder addition port C Put the hopper onto the powder addition port and secure it with the TC clamp 156 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 3 Prepare the disposable bag 6 3 2 Install the disposable bag ...

Page 157: ...t for the Plus and Plus Flex bag assembly In this section See page Section 158 6 4 1 Calibrate the pH probe 163 6 4 2 Prepare the conductivity probe 165 6 4 3 Autoclave probe sheath assembly 168 6 4 4 Insert probes into the disposable bag Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 157 6 Preparation 6 4 Prepare and install the probes ...

Page 158: ...e the pH probe as follows Action Step Take a pH probe out of the packaging 1 Rinse the sensor end of the pH probe with de ionized water 2 Connect the pH probe with the probe cable so that no thread is visible on the probe 3 NOTICE Do not cross thread the probe cable Tighten the connection properly Carefully push the connector together when tightening it 4 158 Xcellerex XDM 50 1000 XDUO 100 1000 mi...

Page 159: ...r display on the I O Cabinet Press MENU 1 1 1 2 3 Result A menu is displayed on the transmitter screen Use the navigation keys to make selections in the menu 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 159 6 Preparation 6 4 Prepare and install the probes 6 4 1 Calibrate the pH probe ...

Page 160: ... probe at pH 10 as follows 4 1 Put the probe in the pH 10 buffer Stir approximately ten times and make sure no air bubbles are present on the probe 2 Press ENTER to start the calibration When the calibration reading is finished the system displays a range of pH values 3 Select the closest value to pH 10 from the list with the navigation keys and press ENTER Result The pH probe is autocalibrated to...

Page 161: ...ng has been completed before pH probe standardization The disposable bag has been filled The contents of the disposable bag have been equilibrated to the process tempera ture The temperature probe has been calibrated See Section 10 8 Temperature probe calibration on page 289 for instructions Follow the instructions below to perform the pH probe standardization Action Step Take a sample of the disp...

Page 162: ...ect Sensor 1 and press ENTER 3 Select pH and press ENTER 4 Select Standardize and press ENTER 5 Enter the externally measured pH value of your sample and press ENTER 6 Press EXIT 3 repeatedly until you reach to the main screen 162 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 1 Calibrate the pH probe ...

Page 163: ...h de ionized water 2 Connect the conductivity probe with the probe cable so that no thread is visible on the probe 3 NOTICE Do not cross thread the probe cable Find the cell constant value in the accompanying manual 4 On the pH conductivity transmitter display on the I O Cabinet press MENU 1 5 1 2 3 Result A menu is displayed on the transmitter screen Xcellerex XDM 50 1000 XDUO 100 1000 mixers Ope...

Page 164: ...The main screen is displayed The conductivity probe is ready to be used Rinse the probe with de ionized water 7 Disconnect the probe cable from the probe 8 This procedure is sufficient for most applications If additional procedures are needed changing an offset or resetting the system refer to the manufacturer s documentation 164 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29...

Page 165: ...e ratchet clamps Prepare for autoclaving Before autoclaving the probe sheath assembly prepare the following Disposable pipette Deionized water Follow the instructions below to prepare the probe sheath for autoclaving Action Step Verify that the probe cable is not connected to the probe 1 Draw 1 to 2 mL deionized water into a disposable pipette 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating...

Page 166: ...steam inside the probe sheath assembly during autoclaving 4 Remove the pipette 5 Verify that the O rings are present on the probe 6 Insert the probe into the probe sheath assembly through the threaded hole in the probe sheath assembly end plug 7 166 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 3 Autoclave probe s...

Page 167: ...embly is ready to be placed in the autoclave Place the probe sheath assembly into the autoclave The paper membrane end of the probe sheath assembly 1 should be lower than the plug end of the assembly Tip Use a probe assembly holder optional to position the probe sheath assembly correctly during autoclaving Contact your GE representative for more infor mation 10 Start the autoclave See Conditions o...

Page 168: ... bag NOTICE Ratchet clamps may break if they are overtightened A ratchet clamp can be released from its tightened state by sliding the interlocked clamp fingers sideways with respect to each other If ratchet clamp fingers cannot be released the ratchet clamp has to be cut open Side cutters or pliers similar to the ones used to remove a cable tie can be used for the purpose Follow the instructions ...

Page 169: ...ollowing illustration 1 Using your fingers loosely tighten the ratchet clamps until the teeth on the clamp are engaged enough to hold the clamp in position 2 to 3 teeth en gaged 2 NOTICE Do not tighten the clamps too much otherwise they prevent the insertion of the probe into the disposable bag Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 169 6 Preparation 6 4 Prep...

Page 170: ...tion 2 to 3 teeth en gaged 4 NOTICE Do not tighten the clamps too much otherwise they prevent the insertion of the probe into the disposable bag Install probe sheath assembly Before inserting the probe sheath assembly into the disposable bag make sure you have a clamp tightening tool accessible Follow the instructions below to install the probe sheath assembly 170 Xcellerex XDM 50 1000 XDUO 100 10...

Page 171: ...nectors 3 Hold the male ACD connector on the probe sheath assembly and align it with the female connector on the probe port on the disposable bag so that the white membrane strips are facing each other as they exit the flat sides of the connectors 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 171 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes...

Page 172: ...bodies of both connectors with one hand grip both white membrane strips with the other hand and pull them perpendicular to the connectors simultaneously away from the bodies of the connectors in one smooth continuous motion 6 172 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag...

Page 173: ...assembly on the short section of silicone tubing between the dispos able bag and the female ACD connector Remove the anti actuation ring which prevents unintentional engagement before the ACD connectors have been correctly connected 7 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 173 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the dispo...

Page 174: ...onnector until the thumb rest meets the body 8 Note A ratchet sound is heard from the male ACD connector during this motion 174 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag ...

Page 175: ...ndication that the connection might not be aseptic immediately clamp off this probe sheath assembly on the short section of silicone tubing be tween the disposable bag and the female ACD connec tor Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 175 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag ...

Page 176: ...the disposable bag compressing the bellows section of the probe sheath assembly 10 Result The bellows section is fully compressed as shown below 176 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag ...

Page 177: ...own that even if a ratchet clamp breaks the probe itself would not be damaged even if it is a pH probe with a glass body Result The tip of the probe extends above the surface at the inside of the disposable bag for about 8 mm The probe is now ready to be connected to the appropriate cable Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 177 6 Preparation 6 4 Prepare an...

Page 178: ...e 12 Collect all loose probe cables and place the cables into the cable holders on the short side of the mixer vessel 13 Clamp off any unused probe port connections 14 178 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag ...

Page 179: ... No additional measures are needed to prevent the probe from sliding out of the disposable bag Install the temperature probe Follow the instructions below to install the temperature probe into the disposable bag Action Step Slowly and carefully remove the zip tie from the thermowell 1 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 179 6 Preparation 6 4 Prepare and in...

Page 180: ...e The connectors and labels on your instrument may differ from the configura tion shown below 2 Carefully insert the temperature probe into the thermowell 3 180 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag ...

Page 181: ...entally removing the temper ature probe from the thermowell 4 Put the temperature probe cable into the cable holders on the short side of the mixer vessel 5 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 181 6 Preparation 6 4 Prepare and install the probes 6 4 4 Insert probes into the disposable bag ...

Page 182: ...el allow monitoring of disposable bag temperature and vessel weight To calibrate the monitors see the instructions in the monitor manufacturer s documen tation 182 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 5 Calibrate the monitors of Xcellerex XDM mixer ...

Page 183: ... to the disposable bag See Illustrations of the Plus Flex bag assembly on page 77 for overview of the disposable bag The following table explains the pump labels Specification Label Addition of acid solution P 201 ACID PUMP Addition of base solution P 202 BASE PUMP Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 183 6 Preparation 6 6 Prepare the pumps ...

Page 184: ... of the liquid flow through the pump when the pump is running in a clockwise direction See the following section for tubing installation instructions 184 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 6 Prepare the pumps ...

Page 185: ... tubing in pump model 313 follow the instructions below Action Step Open the pump head cover 1 Insert the tubing through the pump 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 185 6 Preparation 6 6 Prepare the pumps ...

Page 186: ...f a turn clockwise 4 CAUTION Do not overtighten Do not overtightenthe adjustment wheel on the pumps The flow through the tubing may be cut off Calibrate the pump XDUO mixer pumps are not calibrated 186 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 6 Prepare the pumps ...

Page 187: ...er gives instructions for the operation of both mixers In this chapter See page Section 188 7 1 Safety precautions 190 7 2 Operate Xcellerex XDM mixer 198 7 3 Operate Xcellerex XDUO mixer 229 7 4 Add liquid contents 236 7 5 Add solid contents 240 7 6 Finish a batch run Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 187 7 Operation ...

Page 188: ...ust comply with the national code of practice for biosafety WARNING Clamps on pump tubing Make sure the tubing between the pump and the disposable bag is not blocked or clamped WARNING Slipping hazard Remove any spillage on the floor immediately to minimize the risk for slipping accidents WARNING Ventilation Do not block the ventilation inlets or outlets on the system CAUTION Hot surface Do not to...

Page 189: ...ION Secure pump tubing Make sure that the pump tubing is secure and in good condition before using the pump Do not block or kink the tubing downstream of the pump Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 189 7 Operation 7 1 Safety precautions ...

Page 190: ...his section See page Section 191 7 2 1 Start up the system 192 7 2 2 Operate the agitator motor 196 7 2 3 Monitor temperature and weight 197 7 2 4 Monitor pH and conductivity 190 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 2 Operate Xcellerex XDM mixer ...

Page 191: ... the system To start the XDM mixer turn the system power switch to I ON position Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 191 7 Operation 7 2 Operate Xcellerex XDM mixer 7 2 1 Start up the system ...

Page 192: ...st the minimum working volume This prevents bag damage The minimum working volume depends on the mixer vessel size See Section 10 3 Xcellerex XDM and XDUO mixers minimum working volumes on page 280 for more information Press the green I run button to start the agitator To stop the agitator motor press the red O button 192 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 A...

Page 193: ...before starting the agitator motor and during the run Follow the instructions below to adjust the agitator run conditions Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 193 7 Operation 7 2 Operate Xcellerex XDM mixer 7 2 2 Operate the agitator motor ...

Page 194: ...th the up and down arrow buttons 1 Result The digital display shows the motor speed 194 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 2 Operate Xcellerex XDM mixer 7 2 2 Operate the agitator motor ...

Page 195: ... digital display F Forward the agitator rotates in clockwise direction R Reverse the agitator rotates in counterclockwise direction See Agitation direction on page 67 for more information Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 195 7 Operation 7 2 Operate Xcellerex XDM mixer 7 2 2 Operate the agitator motor ...

Page 196: ...onitoring starts automatically Monitor weight of the disposable bag The lower display shows the mixer weight When the power to the XDM mixer is turned on the weight monitoring starts automatically To tare the mixer weight press the red button 196 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 2 Operate Xcellerex XDM mixer 7 2 3 Monitor temperature and w...

Page 197: ... parameters The transmitter display shows the measured pH and conductivity mS cm values Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 197 7 Operation 7 2 Operate Xcellerex XDM mixer 7 2 4 Monitor pH and conductivity ...

Page 198: ... page Section 199 7 3 1 Start up the system 207 7 3 2 Operate the agitator motor 211 7 3 3 Prepare the pump 215 7 3 4 Control the pH 220 7 3 5 Control the temperature 225 7 3 6 Manage mixer weight 227 7 3 7 Set alarm limits 198 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer ...

Page 199: ...t XDUO mixer Action Step Make sure that the EMERGENCY STOP button is disengaged 1 Turn the system power switch to I ON position 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 199 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 200: ...Type your user name and password in the text boxes Tap OK 2 Result The user is logged in The Login text changes and shows the current user name Note The current user name is shown on all local control software screens 200 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 201: ...n on the top toolbar 3 Result The local control of the mixer is enabled Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 201 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 202: ...llow the instructions below to connect the XDUO mixer to FlexFactory Action Step Log in to local control software as described in Log in on page 200 1 Log in to FlexFactory software as described in FlexFactory Automation User Manual 2 202 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 203: ...een 3 Result XDUO Mixer System Info screen is shown Tap Request FlexFactory Control 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 203 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 204: ...ol Disconnect from Xcellerex FlexFactory Follow the instructions below to disconnect from FlexFactory Action Step Tap INFO on the home screen 1 Result XDUO Mixer System Info screen is shown 204 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 205: ...ta logging saves the data to the memory card on the HMI The data can then be transferred manually to a USB memory stick using the USB port or directly to an external computer using the Ethernet port Follow the instructions below to start or stop logging data Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 205 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up...

Page 206: ...ctive message 2 changes to green Logging Active message To stop logging tap STOP LOGGING 2 Result Data logging stops The STOP LOGGING button text changes to START LOGGING The green Logging Active message changes to gray Logging Inactive message 206 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 1 Start up the system ...

Page 207: ...on Follow the instructions below to start and control the agitator motor Action Step On the home screen make sure that the Min Weight and Max Weight inter locks are not active 1 The inactive interlocks are shown in gray 1 1 2 Note If the Agitator interlock is active shown in orange it is deactivated when the agitator starts Tap Agitation 2 on the home screen to open the Agitator Detail screen 2 Xc...

Page 208: ...he agitator in viscous solutions may cause the agitator blade to decouple A clicking or knocking sound is heard if this happens Decreasing agitator speed helps to prevent the agitator blade from decoupling Note 208 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 2 Operate the agitator motor ...

Page 209: ...he home screen tap Agitation to open the Agitator Detail screen 1 On the Agitator Detail screen tap STOP 2 Result The agitator motor stops Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 209 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 2 Operate the agitator motor ...

Page 210: ... direction Follow the instructions below to change the agitation direction Action Step On the home screen tap Agitation to open the Agitator Detail screen 1 On the Agitator Detail screen drag the toggle button to CCW or CW as applicable 2 210 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 2 Operate the agitator motor ...

Page 211: ...instructions below to change the pump direction Action Step On the home screen tap pH to open the pH Detail screen 1 On the pH Detail screen tap PUMPS SETUP 2 Result The Prime Pumps screen opens Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 211 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 3 Prepare the pump ...

Page 212: ...w direction through the pump Tap BACK to return to the pH Detail screen 4 Prime the pump Follow the instructions below to prime the pump Action Step Make sure the pH probes are installed in the disposable bag See Section 6 4 Prepare and install the probes on page 157 for more information 1 212 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xce...

Page 213: ...wn on the home screen is a valid value 2 On the home screen tap pH top open the pH Detail screen 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 213 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 3 Prepare the pump ...

Page 214: ... pump press and hold Base 5 Result The pump rotates at the 35 of maximum speed CV 35 while the button is pressed Release the button when the pump is primed 6 Tap BACK to return to the pH Detail screen 7 214 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 3 Prepare the pump ...

Page 215: ... to work in Auto or in Manual mode In Auto mode the PLC controls the pH of the disposable bag contents to the setpoint SP In Manual mode the PLC keeps the pump speed at the manually defined CV value of total pump speed range See Work in Manual mode on page 217 for more information Work in Auto mode To set the pH control to work in Auto mode follow the instructions below Action Step On the home scr...

Page 216: ...utton to AIT121 or AIT122 to select the applicable pH probe 2 Type an applicable pH setpoint value into the PHC_125 pH SP text box 3 216 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 4 Control the pH ...

Page 217: ...defined CV pHC_125 Manual CV range 0 to 50 controls the CV of the acid pump SC_201 and the CV range 50 to 100 controls the base pump SC_202 See the table below SC_202 Base CV SC_201 Acid CV pHC_125 Manual CV 0 100 0 0 80 10 0 60 20 0 40 30 0 20 40 0 0 50 20 0 60 40 0 70 60 0 80 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 217 7 Operation 7 3 Operate Xcellerex XDUO ...

Page 218: ... follow the instructions below Action Step On the home screen tap pH to open the pH Detail screen 1 Set the mixer in Manual mode drag the toggle button to Manual 2 218 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 4 Control the pH ...

Page 219: ...bove into the PHC_125 Manual CV text box 3 Result The instrument keeps the pump speed as specified using a split range control loop Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 219 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 4 Control the pH ...

Page 220: ...ly defined CV value to the TCU In both modes the TCU calculates a fixed setpoint SP using the configured range that is specific for the TCU model Work in Auto mode To set the temperature control to work in Auto mode follow the instructions below Action Step On the home screen make sure that no interlocks are active The inactive interlocks are shown in gray 1 220 Xcellerex XDM 50 1000 XDUO 100 1000...

Page 221: ...y the active temperature sensor is a valid value 2 Tap TEMP on the home screen to open the Temperature Detail screen 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 221 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 5 Control the temperature ...

Page 222: ...licable temperature setpoint value into the TC_163 Temperature SP text box 2 5 Set the mixer in Auto mode drag the toggle button to Auto 6 Result The control of mixer vessel temperature is enabled 222 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 5 Control the temperature ...

Page 223: ...e home screen make sure that no interlocks are active The inactive interlocks are shown in gray 1 Tap TEMP on the home screen to open the Temperature Detail screen 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 223 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 5 Control the temperature ...

Page 224: ...ble value of total TCU remote setpoint range into the TC_163 Manual CV text box 2 4 Result The control of mixer vessel temperature is enabled 224 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 5 Control the temperature ...

Page 225: ...rlock Follow the instructions below to tare the mixer vessel weight Action Step Make sure that the disposable bag is empty before starting the tare proce dure The mixer vessel jacket can be filled with the coolant 1 On the home screen tap Weight to open the Weight Detail screen 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 225 7 Operation 7 3 Operate Xcellerex XDU...

Page 226: ...ared The Tare Confirmation screen stays open Verify that the WT_176 Weight PV value is reset to approximately 0 kg 5 Tap BACK 2 to close the Tare Confirmation screen 6 On the Weight Detail screen tap HOME to go back to the home screen 7 226 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 6 Manage mixer weight ...

Page 227: ... screen for each functionality Only Supervisor and Administrator can set the alarm limits Follow the instructions below to set or change the alarm limits Action Step On the navigation toolbar tap the button for the functionality you want to get access to 1 Result The Detail screen opens for the selected functionality Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 227...

Page 228: ...setpoint text boxes 1 3 1 2 Result The alarm limits are set Tap BACK 2 to go back to the Detail screen 4 On the Detail screen tap BACK to go back to the home screen 5 228 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 3 Operate Xcellerex XDUO mixer 7 3 7 Set alarm limits ...

Page 229: ...ids are added through the addition lines The illustration below shows the possible liquid entry points 1 2 Function Part Main addition line Use this line for filling the disposable bag 1 Liquid addition line for small liquid amounts Use this line for final volume adjustment 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 229 7 Operation 7 4 Add liquid contents ...

Page 230: ...the drain line is fully engaged 3 Remove the side access door from 500 and 1000 L mixers Follow the instruc tions below 4 a Hold the door handle tightly b Turn the door counterclockwise c Remove the door Connect the liquid source to the addition line of the bag assembly 5 Tare the mixer weight if your mixer has a weight monitoring option See Tare mixer weight on page 225 for instructions 6 230 Xce...

Page 231: ...ag through the liquid addition line i d 1 Stop filling when the liquid level has reached 3 to 5 cm and the bag begins to adjust to the shape of the mixer vessel 2 Verify that the following conditions are met 3 No folds in the bag assembly Minimal wrinkles in the bag assembly Tip Check for wrinkles at the bag bottom Adjust the bag assembly inside the mixer vessel as follows 4 Adjust the bottom corn...

Page 232: ...id level rises above the lowest edge of the side access opening Finish the addition of liquids To finish the addition of liquids follow the instructions below Action Step Continue filling the disposable bag with liquid During filling gently adjust the bag position so that the bag shape fits the mixer vessel shape Make sure that the bag corners fit into the mixer vessel corners 1 232 Xcellerex XDM ...

Page 233: ...mixer has a weight monitoring option monitor the weight of the added liquid on the local control software home screen XDUO mixer or on the weight monitor display XDM mixer Decrease the filling speed when the weight approaches the designated level 4 Stop filling the bag when the designated liquid weight is reached 5 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 233 7...

Page 234: ...d the powder addition port in place 6 For 50 to 500 L mixers push the powder addition port of the bag into the center opening of the lid 7 Push another lid section in place while keeping the powder addition port in the opening Keep the TC clamp above the lids 8 234 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 4 Add liquid contents ...

Page 235: ...inserted into the opening as shown in the following illustration 9 Adjust the lines through the rectangular lid openings 10 If needed clamp the fill lines and disconnect the liquid source 11 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 235 7 Operation 7 4 Add liquid contents ...

Page 236: ...e end of the liquid addition process if possible Add solid material slowly to avoid supersaturated solutions in the mixer Consider using a hoist when lifting large containers with solid material Add solid material into disposable bag Any additionport with 3 connectionor a powder bag with gasket can be used for addition of solid material Follow the instructions below to add solid contents into the ...

Page 237: ...o 500 L mixers push the powder addition port of the bag into the center opening of the lid 2 Push another lid section in place while keeping the powder addition port in the opening Keep the TC clamp above the lids 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 237 7 Operation 7 5 Add solid contents ...

Page 238: ...hown in the following illustration 4 Disconnect the TC clamp from the powder addition port 5 Remove the protective cap from the powder addition port 6 Make sure that the O ring stays in place on the powder addition port 7 238 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 5 Add solid contents ...

Page 239: ...e agitator motor 9 Add the solids to the bag contents through the hopper 10 When the addition is complete remove the hopper Tip Push the vessel lid section outwards for easier access to the powder addition port 11 Install the protective cap on the powder addition port 12 Install the TC clamp 13 Push the lid back into place around the base of the TC clamp 14 Xcellerex XDM 50 1000 XDUO 100 1000 mixe...

Page 240: ...mation is applicable for both XDM and XDUO mixers In this section See page Section 241 7 6 1 Collect the product 242 7 6 2 Remove the disposable bag 247 7 6 3 Shut down the system 240 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 6 Finish a batch run ...

Page 241: ...ve the mixer vessel lid 2 Open the clamp on the drain line 3 Monitor the draining process to make sure that it continues as expected 4 Gently adjust the disposable bag position during the draining procedure so that the bag edges move towards the drain opening at the bottom of the mixer vessel Tip You can loosen a clamp on a liquid addition line to reduce the vacuum in the disposable bag and facili...

Page 242: ...e sure the disposable bag is empty 1 Verify that the agitator motor is not running See Start and stop the agitator motor on page 192 or Stop the agitator motor on page 209 for instructions how to stop the agitator motor 2 Remove the mixer vessel lid 3 242 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 6 Finish a batch run 7 6 2 Remove the disposable bag...

Page 243: ... a clean place according to manufacturer s instruction 5 Remove the pH and conductivity probes from the disposable bag Clean the probes according to facility procedures Autoclave and store the probes in a clean place according to manufacturer s instructions 6 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 243 7 Operation 7 6 Finish a batch run 7 6 2 Remove the dispos...

Page 244: ...dling magnetic components There is a strong magnetic attraction between the impeller and the motor drive coupling Follow the instructions below to remove the disposable bag from the mixer vessel 244 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 6 Finish a batch run 7 6 2 Remove the disposable bag ...

Page 245: ...c Remove the door Disconnect the agitator drive head by pulling off the impeller baseplate of the disposable bag from the magnetic drive head in the agitator opening 2 Lift the disposable bag out of the mixer vessel 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 245 7 Operation 7 6 Finish a batch run 7 6 2 Remove the disposable bag ...

Page 246: ...amination of the bag prior to disposal rinse the walls of the empty bag with a bleach solution then drain 1 Dispose of the bag assembly according to national and local environmental regulations 2 246 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 6 Finish a batch run 7 6 2 Remove the disposable bag ...

Page 247: ...ixer do the following Action Step Turn the system power switch to O OFF position 1 If required disconnect the power cord 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 247 7 Operation 7 6 Finish a batch run 7 6 3 Shut down the system ...

Page 248: ...s In this chapter See page Section 249 8 1 Safety precautions 250 8 2 Maintenance schedules 253 8 3 Lock Out Tag Out LOTO turn off procedure 255 8 4 Lock Out Tag Out LOTO turn on procedure 257 8 5 Cleaning 259 8 6 Hardware maintenance 263 8 7 Storage moving and reinstallation 248 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 8 Maintenance ...

Page 249: ...ctrical equipment before doing maintenance CAUTION Contamination hazard Before performing any service work on the system make sure that the system has been properly decon taminated NOTICE Always engage the jacking bolts before moving the instrument This prevents damage to the load cells Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 249 8 Maintenance 8 1 Safety preca...

Page 250: ...areas must be clean and free of any hazardous contaminants before a Service Engineer starts maintenance work Please complete the checklist in the On Site Service Health and Safety Declaration Form or the Health and Safety Declaration Form for Product Return or Servicing depending on whether the instrument is going to be serviced on site or returned for service respectively Copy the form you need f...

Page 251: ...d person nel Inspect cables and con nectors Annuallyandafter system relocation Inspect hinges and han dles Inspect jacking bolts on page 259 Properly trained person nel Inspect jacking bolts If anything abnormal is found contact your GE representative for ser vice Properly trained person nel Inspect pressure relief assembly Inspect pump heads Inspect the I O Cabinet Inspect vent and drain valves V...

Page 252: ...e calibration Beforeeachbatch Section 10 8 Temperature probe calibration on page 289 Calibration technician Temperature probe cali bration Semi annually or as needed See the manufacturer s manual GE service engineer or personnel trained by GE Calibration of weight monitoring function 1 weight calibration Annually See the manufacturer s manual Calibration technician Conductivity transmitter calibra...

Page 253: ...ltage It is essential for the safety of personnel working in or around electrically powered equipment to follow a company policy and procedure for Lock Out Tag Out LOTO Turn off the instrument Follow the instructions below to turn off XDM or XDUO mixer Action Step Turn the system power switch to O OFF position 1 Attach a tag out device onto the system power switch 2 Xcellerex XDM 50 1000 XDUO 100 ...

Page 254: ...3 For a jacketed mixer empty the mixer vessel jacket as described in Empty the vessel jacket on page 127 4 For a jacketed mixer attach a tag out device onto the mixer vessel coolant inlet 5 254 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 8 Maintenance 8 3 Lock Out Tag Out LOTO turn off procedure ...

Page 255: ... policy and procedure for Lock Out Tag Out LOTO Turn on the instrument Follow the instructions below to turn on XDM mixer or XDUO mixer Action Step For a jacketed mixer if your mixer should be connected to a TCU remove the tag out device from the mixer vessel coolant inlet 1 For a jacketed mixer connect the coolant tubing and fill the mixer vessel jacket as described in Section 5 4 Connect tempera...

Page 256: ...Action Step Turn the system power switch to I ON position 4 256 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 8 Maintenance 8 4 Lock Out Tag Out LOTO turn on procedure ...

Page 257: ...ever immerse any part of the equipment in liquid or spray liquid on the equipment Always make sure that the equipment is com pletely dry before plugging it in Always follow all environmental health and safety guidelines pertaining to the materials used Resistance to cleaning agents XDM and XDUO mixers are resistant to the following cleaning agents Concentration Cleaning agent Undiluted Actril Dilu...

Page 258: ...ior of the mixer vessel and the I O Cabinet 2 Check all stainless steel components for signs of surface rust If rust is found do as follows 3 1 Scrub areas of surface rust with an extra fine mildly abrasive cleaning pad 2 Wipe the treated areas with a surface passivation chemical 3 Wipe the treated areas with a cloth soaked in Water For Injection WFI to remove the chemical 258 Xcellerex XDM 50 100...

Page 259: ...th and safety standards and practices as estab lished within the country where the equipment is installed Local provincial bylaws must be followed The owner of the instrument is responsible that relevant standards and practices are followed and a safe operating environment is maintained Inspect jacking bolts Verify that the jacking bolts are not damaged or worn If damage to the bolts is found repl...

Page 260: ...remove the ruptured burst disc 3 Insert the new burst disc See the manufacturer s documentation for more information 4 Attach the clamp 5 Close the clamp with the screw 6 260 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 8 Maintenance 8 6 Hardware maintenance ...

Page 261: ...the mixer weight See Tare mixer weight on page 225 for instructions 2 Use water or weights to increase the mixer weight 3 Add a known quantity of water into the disposable bag installed inside the mixer or place a known quantity of weights onto the mixer Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 261 8 Maintenance 8 6 Hardware maintenance ...

Page 262: ...s to the added weight 4 Result Mixer weight monitoring functionality is verified Note If the weight reading is not correct contact your GE representative for assis tance 262 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 8 Maintenance 8 6 Hardware maintenance ...

Page 263: ...ion Contact your GE representative for instructions on how to store move and re install the instrument Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 263 8 Maintenance 8 7 Storage moving and reinstallation ...

Page 264: ...sts contact GE for service The motor is overloaded Variable frequency drive VFD is not functioning as expected Connect the power cable Power cable is not connected Contact your GE representative to replace the drive The drive is broken Refer to the VFD manufacturer s manual for error code clarifica tion If the problem cannot be solved on site contact your GE representative for help Software or mec...

Page 265: ...f E STOP Enable the agitator See FlexFactory Automation User Manual for more information The agitator is not enabled The agitator does not start on FlexFactory controlled mixer Tap RESET on the local control software screen and start the agitator when the system has been restarted after emergency shutdown Note The agitator cannot be started while the system is in the state E STOP The system is in ...

Page 266: ... Corrective action Possible causes Problem Connect the power cable Power cable is not connected The local control panel does not function Contact your GE representative for replacement cable The main power cable is dam aged Contact your GE representative for possible replacement The I O Cabinet is broken The home screen does not show up on the local control panel al though the system is plugged in...

Page 267: ... is empty Prime the pumps The pumps are not primed Free the feed line Feed line before or after the pump is kinked Free the feed line Feed line before or after the pump is clamped Conduct a study to verify the control parameters The following factors have been identified as important PID parameters are not appropriate for the system Quantity of media The pump type Concentration of acid and base Ma...

Page 268: ...with isopropyl or methyl alcohol to remove the water from beneath the con tacts Note Do not immerse the plug ends in liquid Use an aerosol spray to introduce the alcohol pH or conductivity connector was wetted and did not dry completely Measurement value is not as expected Make sure all probes are stan dardized prior to installation The probe was not standardized prior to installation into the dis...

Page 269: ...t or right All tubing used in the pumps will wear out with use over time The tubing is worn out Use only tubing rated for use in peri staltic pump head Verify that the cause of the E STOP condition is eliminated and clear the E STOP Try to use the pumps again The system is in E STOP state The pump is not turning Clear the interlock condition An interlock is active See Section 2 4 Xcellerex XDUO mi...

Page 270: ... is yes the connection is working properly 4 If the display message is no the connection is not functioning Check the connection cable be tween the TCU and PLC Check if the connection between the I O Cabinet and TCU is functioning properly Do the following There is no connection between the I O Cabinet and the Mokon TCU 1 Verify that the controller located on the front of the TCU is pow ered 2 Dis...

Page 271: ...epart ment to perform a cornering test and determine which load cell has failed Load cell has failed physically or electrically broken Verify that the mixer vessel legs are free of any obstructions or blocking objects Physical obstruction of load cell motion Disengage the jacking bolt See Disengage jacking bolts on page 135 for instructions Note If the mixer was filled while the jacking bolt was e...

Page 272: ...r weight is within the operationalrange Verify that the mixer vessel legs are free of any obstructions or blocking objects Physical obstruction of load cell motion Disengage the jacking bolt See Disengage jacking bolts on page 135 for instructions Note If the mixer was filled while the jacking bolt was engaged the weight measurements of the batch are not accurate Jacking bolt is engaged Contact yo...

Page 273: ... System specifications 279 10 2 SP CV and PV units and ranges 280 10 3 Xcellerex XDM and XDUO mixers minimum working volumes 281 10 4 Pump characteristics 282 10 5 Disposable bag specifications 283 10 6 Environmental requirements 284 10 7 Temperature control unit 289 10 8 Temperature probe calibration 294 10 9 Ordering information 295 10 10 Health and Safety Declaration Forms Xcellerex XDM 50 1000...

Page 274: ...XDM 50 Dimensions W H D 970 1090 870 mm 38 43 34 in XDM 100 1100 1120 1000 mm 43 44 39 in XDM 200 1300 1480 1200 mm 51 58 47 in XDM 500 1500 1590 1410 mm 59 62 55 in XDM 1000 100 kg 220 lb XDM 50 Weight 140 kg 310 lb XDM 100 185 kg 410 lb XDM 200 300 kg 660 lb XDM 500 425 kg 940 lb XDM 1000 2 5 L XDM 50 Jacket volume 3 8 L XDM 100 4 0 L XDM 200 8 0 L XDM 500 9 0 L XDM 1000 274 Xcellerex XDM 50 100...

Page 275: ...nstruction material Polycarbonate Lid Stainless steel nylon polyurethane Casters 70 dB A XDM 50 to 1000 Sound level Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 275 10 Reference information 10 1 System specifications ...

Page 276: ...770 mm 39 44 30 in XDM 200 1190 1480 970 mm 46 58 38 in XDM 500 1390 1590 1180 mm 54 62 46 in XDM 1000 85 kg 190 lb XDM 50 Weight 100 kg 220 lb XDM 100 125 kg 280 lb XDM 200 185 kg 410 lb XDM 500 295 kg 650 lb XDM 1000 Stainless steel Vessel Construction material Polycarbonate Lid Stainless steel nylon polyurethane Casters 70 dB A XDM 50 to 1000 Sound level 276 Xcellerex XDM 50 1000 XDUO 100 1000 ...

Page 277: ... XDUO 200 1350 1480 1200 mm 53 58 47 in XDUO 500 1550 1590 1410 mm 61 62 55 in XDUO 1000 155 kg 340 lb XDUO 100 Weight 200 kg 440 lb XDUO 200 315 kg 690 lb XDUO 500 440 kg 970 lb XDUO 1000 3 8 L XDUO 100 Jacket volume 4 0 L XDUO 200 8 0 L XDUO 500 9 0 L XDUO 1000 Stainless steel Vessel Construction material Polycarbonate Lid Stainless steel nylon polyurethane Casters 70 dB A XDUO 100 to 1000 Sound...

Page 278: ...44 30 in XDUO 200 1240 1480 970 mm 48 58 38 in XDUO 500 1440 1590 1180 mm 56 62 46 in XDUO 1000 115 kg 250 lb XDUO 100 Weight 140 kg 310 lb XDUO 200 200 kg 440 lb XDUO 500 310 kg 680 lb XDUO 1000 Stainless steel Vessel Construction material Polycarbonate Lid Stainless steel nylon polyurethane Casters 70 dB A XDUO 100 to 1000 Sound level 278 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Inst...

Page 279: ...gitator speed 0 to 150 mS cm Not applicable Not applicable Conductivity 0 to 14 0 to 100 0 to 14 pH Not applicable 0 to 100 Not applicable Pumps 0 C to 100 C 0 to 75 0 C to 60 C Vessel temperature The following table shows the upper limit for vessel weight PV for all XDUO mixer sizes Maximal PV kg Mixer vessel size 125 100 L 250 200 L 625 500 L 1250 1000 L Xcellerex XDM 50 1000 XDUO 100 1000 mixer...

Page 280: ...es Minimum working volume L Mixer vessel size 17 50 L 28 100 L 44 200 L 76 500 L 119 1000 L 280 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 3 Xcellerex XDM and XDUO mixers minimum working volumes ...

Page 281: ...speed Low speed Tubing i d Maximal flow rate Maximal speed Maximal flow rate Maximal speed 0 35 L min 350 rpm 0 1 L min 100 rpm 3 2 mm 1 75 L min 350 rpm 0 5 L min 100 rpm 8 mm Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 281 10 Reference information 10 4 Pump characteristics ...

Page 282: ...embly is between 10 C and 34 C Information about the storage temperature is shown on the bag label Operating temperature The disposable bag assembly is rated for temperatures between 5 C and 65 C 282 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 5 Disposable bag specifications ...

Page 283: ...owed location 5 C to 30 C Ambient temperature operation 20 to 85 RH non condensing Max relative humidity operation 20 C to 60 C Ambient temperature transportation 20 C to 50 C Ambient temperature storage Up to 2000 m Altitude operation Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 283 10 Reference information 10 6 Environmental requirements ...

Page 284: ...d specifications for TCU In this section See page Section 285 10 7 1 TCU requirements 287 10 7 2 Temperature control optimization 288 10 7 3 TCU coolant specifications 284 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 7 Temperature control unit ...

Page 285: ...XDUO mixers only Required On Off emergency stop TCU requirements 500 L 1000 L mixer Value Parameter Property 9 kW Cooling capacity 500 L mixer General requirements 15 kW Cooling capacity 1000 L mixer 9 kW Heating capacity 500 L and 1000 L mixer 2 8 bar 40 psi g Fluid outlet pressure Process requirements 60 L min Fluid outlet flow 10 C Fluid outlet minimum temperature 65 C Fluid outlet maximum temp...

Page 286: ...oint Remote control interface for XDUO mixers only Required On Off emergency stop 286 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 7 Temperature control unit 10 7 1 TCU requirements ...

Page 287: ...ts weight or if a different TCU is used the vessel temperature control can be optimized for these conditions The PID parameter values shown in the table below are given as starting points for further opti mization of the temperature control D Term I Term P Term Mixer 0 default 1200 default 10 default XDUO 100 XDUO 200 0 default 1200 default 40 default XDUO 500 XDUO 1000 The PID parameters are defi...

Page 288: ...s 7 8 pH None CO2 aggressive 0 3 mg L Iron 0 05 mg L Manganese 250 mg L Sulfate 250 mg L Chloride 40 mg L COD 1000 CFU mL Bacteria TCU coolant composition The use of corrosion inhibitor in the coolant is optional If the vessel jacket temperature is expected to be below 6 C antifreeze needs to be added to TCU coolant The table below shows an example coolant composition containing corrosion inhibito...

Page 289: ...our instrument configuration Both sensors have to be calibrated simultane ously Note Preparation Before you start to calibrate the temperature probe prepare the following Temperature calibration instrument The accuracy of the temperature calibration instrument is the responsibil ity of the site metrology department Note Constant temperature circulating bath If additional circulating baths are avai...

Page 290: ...t Make sure that the temperature probe is inserted into the liquid by at least 7 5 cm Note Do not wet the probe connector 3 Wait until the system reaches the equilibrium 4 Record the data for both the temperature probe and the standard probe as follows 5 The data for the temperature probe is displayed on the local control software home screen If the probe contains two temperature sensors record th...

Page 291: ...ment If the temperature probe is out of tolerance follow the steps below to adjust the probe Action Step Using the data obtained during the calibration procedure calculate the offset to adjust the probe temperature to the recorded standard probe temperature 1 Offset standard temperature reading probe reading Note Use the data obtained at operating temperature the middle calibration point for best ...

Page 292: ...emperature Detail screen On the Temperature Detail screen tap OFFSETS Result The Transmitter Offsets screen opens 292 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 8 Temperature probe calibration ...

Page 293: ...t the operating temperature does not bring the system into tolerance replace the temperature probe and repeat the calibration procedure If the calibration of the new temperature probe does not bring the system into tolerance contact your GE representative for service Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 293 10 Reference information 10 8 Temperature probe ca...

Page 294: ...tions Literature Service Training Ordering information Contact information Contact information can be found on the back page of this document For more advanced technical information contact the manufacturer See Manufacturing information on page 11 294 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 9 Ordering information ...

Page 295: ...ablesurvey Adequate space andclearance is providedto allowsafe access forinstrumentservice repairor installation Insome cases this mayrequirecustomerto move equipmentfrom normaloperatinglocation prior to GE arrival Consumables suchas columns orgels have beenremovedor isolatedfromthe instrument andfrom any areathat may impede access tothe instrument All buffer waste vessels are labeled Excess conta...

Page 296: ...ological substances pleasespecify OtherHazardous Chemicals please specify Equipment must be decontaminatedpriortoservice return Pleaseprovide atelephone number whereGE cancontact youfor additionalinformationconcerningthe system equipment Telephone No Liquid and orgas in equipment is Water Ethanol None empty Argon Helium Nitrogen Liquid Nitrogen Other please specify Equipment type ProductNo SerialN...

Page 297: ...Following this information section the following appendices are found in this manual Appendix B Add and remove users on page 298 Appendix C Download audit and data logs on page 304 Appendix D Privacy and security on page 310 The Appendices are provided in English only Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 297 A Information about the appendices ...

Page 298: ...ilable to Administrator Manage the Administrator account The factory settings for Administrator account in XDUO mixer local control software are as follows User ID Administrator Password admin It is recommended to change the Administrator account password before starting to use the instrument Follow the instructions below to change the password Action Step Log in as Administrator using factory set...

Page 299: ...to open the XDUO Mixer System Info screen 2 Tap USER ADMIN on the XDUO Mixer System Info screen to open the User Administration screen 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 299 B Add and remove users ...

Page 300: ...box 4 Type the new password in the text box and tap Return 5 Result The password dialog box re opens Close the dialog box by tapping the close button 6 Result The new administrator password is saved and hidden 300 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD B Add and remove users ...

Page 301: ...ose the dialog box by tapping the close button 5 Result The new password is saved and hidden Tap the new user row in the Group column 3 to open the group list 6 In the group list tap the applicable group name Tap Return 7 Tap the new user row in the Logoff time column 4 Note The logoff time specifies how long time a user can be inactive before being automatically logged out 8 Type the applicable t...

Page 302: ...e the new information in the dialog box and tap Return 3 Result The new entry is recorded in the software The user cannot log in with previous name or password anymore Tap the user row in the Group column 3 for the applicable user 4 In the group list tap the new group name Tap Return 5 Delete a user account Follow the instructions below to delete a user account Predefined users for example Adminis...

Page 303: ...elete the user name and tap Return 2 Result The user account is deleted NOTICE Do not delete the HMIAdmin account This account is used by GE service personnel Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 303 B Add and remove users ...

Page 304: ...efinition Term Abbreviation 0 to 100 Pump 1 speed SC201_Acid_PID_Out put 0 to 100 Pump 2 speed SC202_Base_PID_Out put Not applicable pH AIT121_PH1_PV Not applicable pH1 AIT122_1_PH2_PV millisiemens per centimeter mS cm Conductivity2 AIT122_2_Conductiv ity_PV As applicable Process variable PV revolutions per minute rpm Agitator speed SC244_Agitator_PV C Temperature sensor 1 TE161_Tempera ture1_PV C...

Page 305: ...nderside of the I O Cabinet 1 Open a web browser on the computer 2 Type 172 20 42 152 into the web browser address bar 1 and tap Enter 3 Result The HMI Miniweb start screen opens 1 2 Click the Login link in the upper left corner of the screen 2 and log in using the Windows CE administrator account password 4 User ID Administrator Password admin Result You are logged in The link name changes to Log...

Page 306: ...n Step Click File Browser in the left pane 5 Click Storage Card SD in the File Browser pane 6 306 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD C Download audit and data logs ...

Page 307: ...e data verify that the computer region and language settings in Control Panel are set to English United States This makes sure that your time data format is compatible with Excel Tip Download the logs using a USB memory stick Follow the instructions below to download the audit or data logs with a USB memory stick Action Step Remove the protective cover from the USB connection port on the front of ...

Page 308: ...a tion about administrator account 2 Tap INFO on the home screen to open the XDUO Mixer System Info screen 3 Tap CONTROL PANEL on the XDUO Mixer System Info screen to open the Windows CE Control Panel 4 Browse to My Computer Storage Card SD 5 308 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD C Download audit and data logs ...

Page 309: ...t menu click Paste 9 Remove the USB memory stick from the connection port and install the protective cover 10 If you want to create a graph using your exported time data verify that the computer region and language settings in Control Panel are set to English United States This makes sure that your time data format is compatible with Excel Tip Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating I...

Page 310: ...anagement of cyber security threats GE recommends to implement cyber secure operation as part of an overall defence in depth information assurance strategy that is used throughout an Information Technol ogy environment The strategy should address personnel physical security and technol ogy issues The layered approach of defence in depth strategy limits the risk that the failure of a single securit...

Page 311: ...er should use an effective arrangement for isolating and protecting the network for example implementing firewall protection demilitarized zones DMZs virtual Local Area Networks VLANs and network enclaves Connection of the product to a network that includes other equipment may expose the product to other unidentified cyber security risks The responsible parties in the customer organization should ...

Page 312: ...of this Appendix Cyber security vulnerability GE works closely with the third party software suppliers to monitor and evaluate cyber security vulnerabilities applicable to this product This work includes vulnerabilities in the application software third party components and the underlying operating system Vulnerabilities in the operating system or in other third party components are assessed based...

Page 313: ...9 troubleshooting 265 Agitator blade slipping 208 Agitator Detail screen 100 Agitator speed measuring units 279 Alarm Critical Alarm 96 set limits 227 Alarm configuration screen 95 illustration 97 Alarm overview screen 94 Ambient environment 119 Aseptic connection device ACD 82 connector 167 171 Audit logs download 304 Autoclave probe 165 probe sheath assembly 165 Auto mode 88 B Bag add liquids 22...

Page 314: ...12 Data export 304 Data logging start or stop 205 Data logs download 304 Data storage cyber security 312 Deadband 267 Delete user account 302 Dimensions 274 276 278 Disconnect FlexFactory 204 lines 242 probe 242 Disposable bag 76 add liquids 229 add solids 236 decontaminate 246 insert probe sheath 170 installation 147 loading 147 remove 244 temperature resistance 81 282 uninstall 244 unpacking 140...

Page 315: ...r 232 Installation 116 Interlocks 43 220 223 Agitator 43 high weight 43 local control software 44 Max Weight 43 Min Weight 43 status 44 J Jacket emptying 127 filling 124 volume 123 Jacketed mixer 54 system specifications 274 277 Jacking bolts disengage 135 engage 133 function 68 illustration 69 maintenance 259 L Labels 29 safety 33 Lid illustration 65 Liquid addition 229 Load cells function 68 ill...

Page 316: ... loop 215 troubleshooting 267 268 pH control Auto mode 215 Manual mode 217 split range loop 215 pH Detail screen 103 pH PID Settings screen 105 pH probe calibration 158 illustration 82 insert into probe sheath 166 standardization 161 PID parameters TCU 287 temperature control 287 PolyScience TCU troubleshooting 270 Power failure 42 Prime pumps 212 Privacy and security 310 Probe autoclave 165 disco...

Page 317: ...tion 252 maintenance 251 Screens Agitator Detail 100 alarm configuration 95 alarm overview 94 Conductivity Detail 102 home screen 85 pH Detail 103 pH PID Settings 105 Temperature Detail 107 Temperature PID 109 Time Management 92 Transmitter Offsets 111 Trend 113 Weight Detail 112 XDUOMixerSystemInfo 90 Security cyber security 310 Security levels 46 Setpoints units 279 Set time and date 92 Shut dow...

Page 318: ...unctioning 271 Transmitter Offsets screen 111 Transport unpacked 121 Trending ranges 114 Trend screen 113 Troubleshooting 264 agitation XDM mixer 264 burst disc 266 conductivity 268 load cells 271 local control panel 266 pH 267 268 pumps 269 TCU 270 temperature control 270 temperature monitor ing 271 weight monitoring 271 Tubing install in pumps 185 Turn off mixer 247 Typographical conventions 8 U...

Page 319: ... illustration 55 monitor weight 196 operation 190 pH 197 restart 35 start 191 start agitator 192 stop agitator 192 tare weight 196 temperature 196 XDUO mixer agitator direction 210 control 72 emergency shutdown 37 FlexFactory component 73 FlexFactory control 73 illustration 60 operation 198 restart 38 start 199 start agitator 207 stop agitator 209 XDUO Mixer System Info screen 90 Xcellerex XDM 50 ...

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Page 322: ...roperty of their respective owners 2017 2018 General Electric Company All goods and services are sold subject to the terms and conditions of sale of the company within GE Healthcare which supplies them A copy of these terms and conditions is available on request Contact your local GE Healthcare repre sentative for the most current information GE Healthcare Europe GmbH Munzinger Strasse 5 D 79111 F...

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