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Operation Manual 

V1.0

 

 

 

 

 

MP9604 

 

 

 

 

 

 

 

 

 

 

Summary of Contents for AutoMATE 96

Page 1: ...Operation Manual V1 0 MP9604 ...

Page 2: ......

Page 3: ...nt If service is required the box will be needed to ship the instrument to our Service Department Initial Inspection Please inspect the instrument as well as all included accessories when you first open the packaging If you find anything damaged or missing please contact Benchmark Scientific or your local distributor immediately BENCHMARK SCIENTIFIC ACCURIS INSTRUMENTS PO Box 709 Edison NJ 08818 U...

Page 4: ... voiding the warranty the operator should not attempt to repair the instrument without explicit guidance from Accuris Instruments If service is required please contact Accuris Instruments or your local distributor for repair Before powering on confirm that the voltage used meets the electrical requirements of the instrument as stated on the rating plate If the electric cord is damaged replace it w...

Page 5: ...bnormal sound or smell The instrument is dropped or there is any damage to the housing Any malfunction 3 Maintenance The instrument should be cleaned regularly using a soft cloth dampened with a small amount of alcohol 4 Transportation and storage requirements Ambient temperature 20 55 Relative humidity 80 Place in a well ventilated room away from corrosive gas ...

Page 6: ...ule structure 13 3 96 to 384 operation 14 Chapter 4 Use of Instrument 15 1 Check before experiment runs Error Bookmark not defined 2 Software Usage Guide 18 2 1 Start software Error Bookmark not defined 2 2 Main interface of software 19 2 2 1 Basic Mode 19 2 2 1 1 Position Error Bookmark not defined 2 2 1 2 Position settings Error Bookmark not defined 2 2 1 3 Information 22 2 2 1 4 Function Error ...

Page 7: ...3 Default Tips 36 2 2 3 2 System 36 2 2 3 3 Maintenance 39 2 2 4 Labware 40 2 2 5 User Settings 43 2 2 5 1 User settings 43 2 2 5 2 Change user 45 2 2 6 SWITCH button function 46 Chapter 5 Product Maintenance 47 1 Maintenance tool 47 2 Daily maintenance 47 3 Regular maintenance 48 4 Annual maintenance 48 Chapter 6 Troubleshooting 48 1 Common failure and solutions 48 2 Software Error Alarm List 49 ...

Page 8: ...cisely aligns the tips with the appropriate microplate reservoir Once programmed the instrument can run protocols to completion without any manual positioning or adjustment Three interchangeable heads allow for a pipetting range from 1 0µL to 1000µL The AutoMATE 96 is compact enough to fit onto a standard lab bench or into a biosafety cabinet 1 Key Features Precise pipetting The pipetting range ca...

Page 9: ... Model AutoMATE 96 MP9604 Pipetting Heads 20ul 200ul 1000ul interchangeable Platform positions Four Plate positioning Automatic motorized Operation interface Tablet basic mannual operation and progremmed operation Channels 8 96 Compatible Tips Accuris AutoMATE tips Operating Android Display 8 inch tablet color display Instrument port USB B Power supply 100 to 240VAC 50 60Hz 100W Tablet connection ...

Page 10: ...000 µL Number of pipetting channels 96 96 96 Pipetting range µL 1 20 5 200 100 1000 Pipetting accuracy 1µL 12 5µL 5 100µL 2 5 2µL 5 20µL 2 500µL 1 10µL 1 100µL 1 1000µL 1 20µL 1 200µL 1 Pipetting precision 1µL 10 5µL 3 5 100µL 1 25 2µL 5 20µL 1 5 500µL 0 4 10µL 1 100µL 0 8 1000µL 0 4 20µL 0 8 200µL 0 4 ...

Page 11: ...11 4 Dimensions Fig 1 Dimensions ...

Page 12: ...1 Structure Fig 1 AutoMATE 96 Structure 1 Shell 2 Front casing 3 Tablet 4 Pipette Head 5 Front Plate 6 4 position motorized platform 7 Operational LED Indicator 8 SWITCH key 9 Instrument Base 10 USB Inlet 11 Power switch 12 Power Inlet ...

Page 13: ...Pipette Head Installation Replacement Push front casing up Remove the front edge Loosen the locking levers Replace pipetting head Tighten levers Replace front casing front edge Fig 3 Pipette Head Replacement ...

Page 14: ...Place the 384 well microplate onto the bottom left side of the adapter During a program run the AutoMATE 96 will dispense into two horizontal positions and then instruct the user to move the 384 well microplate to the top left side of the adapter to dispense into the final 2 horizontal positions 384 well Microplate Positioning ...

Page 15: ...uct is designed for indoor use only Operating temperature range 10 40 Relative humidity below than 80 no condensation Atmosphere pressure 86 0 k Pa 106 0k Pa Power input 100 240VAC 50Hz 60Hz Power sockets must be properly grounded The minimum distance between the back of the instrument and the wall is 10 cm The instrument should be installed on a stable surface with dimensions of at least 730X360m...

Page 16: ...ery is charged appropriately for use with the included adapter and cord Open the Auto Mate 96 series app on the tablet 1 4 Check the Software Version After opening the Auto Mate 96 app check the instrument software version on the start up screen The software version displayed on this interface should be the same that is recorded in the product performance test table See Fig 1 Fig 2 Software versio...

Page 17: ...ruments or the relevant distributor should be contacted Before beginning any pipetting process the following checklist should be completed Confirm that the tablet controller is connected to the instrument Ensure that there are no obstructions to the moving platform and that it moves freely to both the right and left Verify that the power supply connected to the instrument is steady and meets the p...

Page 18: ...lect the AutoMATE 96 app icon to enter the application interface Fig 4 AutoMATE 96 App Icon Select the user Admin or other enter the corresponding user password and click Login to enter the main interface as shown in the figure below Fig 5 Login interface ...

Page 19: ...g in the main interface will display Figure 8 On the main interface choose one of the two pipetting modes Manual Mode or Automated Program Mode as shown in the figure below Fig 6 AutoMATE 96 Application Main Interface 2 1 1 Manual Mode ...

Page 20: ...2 and so on To change to another platform in the Manual Mode Interface select a different platform position to highlight it blue Figure 10 the instrument will automatically position itself to the platform position specified Fig 8 Platform Position Selection Tip Loading Ejection To load eject pipette tips in the Manual Mode Interface select the Load Tips or Eject Tips icons to highlight it blue Fig...

Page 21: ...tion Pipetting Functions In the Manual Mode Interface users can toggle amongst settings for Aspirate Dispense and Mix Figure 12 Fig 10 Manual Mode Pipetting Functions Table 1 Legend Manual Mode Pipetting Functions Aspiration volume Click the Aspirate volume text box enter the volume of liquid to be ...

Page 22: ...ition or click the drop down menu to choose an available dispensation position Mix position mm Click to create a new mix position or click the drop down menu to choose an available mix position Liquid type Click the drop down to select the liquid type of the sample Water Alcohol Lysis Buffer Magnetic Beads etc Positions for aspirate dispense and mix refer to position location of the bottom of the ...

Page 23: ...osition data will not be displayed Fig 11 Manual Mode Function Keys Real Time Information In the Manual Mode Interface real time information of the pipette tips such as the volume of liquid in the tips and position of the tips can be seen Below the position of the tip can be manually adjusted according to the current position Highlight the Aspirate Dispense Position box to enable automatic aspirat...

Page 24: ... right New Save as Manage and Records 2 2 2 1 New Press the New button to create a new program The default program name is the numerical combination of the current date and time see Fig 15 Select step click on this number to change the name if desired then press OK to start the programming Press New Step at the lower left and the Select step window till open Press to highlight the type of step to ...

Page 25: ... far left position of the platform Select the platform position P1 Next press the Labware list button to choose the appropriate tips to load Fig Or if pipetting with only a column of 8 tips for a process such as serial dilution choose Load by column Choose the column of tips 1 to 12 which is to be loaded on the left most column of the pipetting head See figure x Unloading tips carry the same param...

Page 26: ...e step parameters click on New Step to add another step The program can be saved by pressing the disk icon in the upper right of the screen Steps can be modified by pressing any of the created steps in the upper left Automated Program Mode Aspirate Dispense Settings ...

Page 27: ...27 Automated Program Mode Pause Rinse Settings ...

Page 28: ... Save as To save an existing program under a new name highlight the desired program click the Save as option and enter a new name This will create a copy of the program with the new name which can then be modified according to the user s requirements ...

Page 29: ... as protocol 2 2 2 3 Manage The Manage function enables users to manage the stored programs in the system With it they can select a program to modify delete or even export and import it to and from a USB flash drive ...

Page 30: ...a of the instrument To view detailed usage data users can double click on any record If a user wants to delete a record or export import it to from a USB flash drive they can click the check box on the left of the record Additionally the user may also select multiple records for importing or exporting using this function ...

Page 31: ...protocol and click the Preview button as shown in Figure 37 From the preview screen the user can click the Run button to start the protocol or press the icon at the top left of the screen to return to the protocol list screen Additionally users may also be able to control the settings of the protocol from this screen including the name and accessibility ...

Page 32: ...rm prompt box before running 2 2 2 6 Running a protocol From the protocol list screen Figure 20 click to highlight a single protocol then click the Run button A window will appear to confirm all consumables are placed properly before starting the run ...

Page 33: ...g of the run as shown in Figure 40 and clicking OK will stop the current protocol The pipetting head and motorized platform will return to the home position To Pause a run the user can press the Pause button The run can then be resumed by pressing Continue or stopped by pressing Stop Additionally users may also be able to view the progress of the run from this screen ...

Page 34: ...gs mode can be selected from the upper left menu The settings interface includes three sections parameter system and maintenance Fig 24 Settings 2 2 3 1 Parameters settings Parameters setting allows adjustments to Liquid parameter Speed parameter and Default Tips per figure 43 ...

Page 35: ...rate aspiration and dispensing The liquid parameter management interface allows adding or removing different liquids from the selection list and adjusting parameters for the different liquids Liquid parameters can also be imported from or exported to a USB drive Fig 26 Liquid Parameter Management Interface 2 2 3 1 2 Speed parameter ...

Page 36: ...meter interface allows adjusting the speed and acceleration values of the X axis motorized platform and Z axis pipetting head 2 2 3 1 3 Default Tips Fig 28 Default tips interface Default tips interface can set default for tips 2 2 3 2 System ...

Page 37: ...electing Language Time Screen brightness Firmware Upgrades and Bluetooth options For firmware upgrades insert a USB drive with updated firmware files to perform updates Fig 320 Fig 29 System settings interface Fig 30 Time settings ...

Page 38: ...38 Fig 32 Bluetooth Settings Fig 31 Screen brightness settings ...

Page 39: ... settings Fig 34 Bluetooth settings Fig 35 Restore the factory setting 2 2 3 3 Maintenance In the Settings mode select Maintenance to enter the maintenance interface Base calibration and Pipettor calibration adjustments should be performed by ...

Page 40: ...t for pipettor head replacement in Section 2 Click the icon to scan the QR code label on the pipetting module using the rear camera of the tablet This automatically loads the specific calibration data for the pipetting module Fig 36 Pipettor calibration Fig 37 Prompt box for pipette head replacement 2 2 3 Labware management From the main settings menu click Labware to enter labware management inte...

Page 41: ...erface To add a new consumable that can be selected during programming choose the type of consumable listed under Labware then click the new box which is the box with the in the center see Fig 39 A brand can be selected or a new brand can be added After entering a new brand and saving the newly created ...

Page 42: ...see Fig 39 Basic parameters such as well shape well volume dimensions and liquid levels can be adjusted see Fig 41 Fig 420 Fig 43 The bottom and top of the liquid interface respectively represent the distance between the tips and the bottom when aspirate the distance between the tips and top when dispensing Fig 41 Basic parameter interface Fig 42 Dimension interface Fig 43 Liquid interface ...

Page 43: ...ions including Account Administration and Switch User as shown in the image above 2 2 5 1 User settings Per Fig 44 the Account Admin icon to enter user settings interface Click Password to change the Admin password and click Manage to add or remove user accounts Fig 45 Change password interface Account Admin Switch User ...

Page 44: ...44 Fig 46 User manage interface Fig 47 Change username interface Fig 48 Reset password interface Fig 49 Delete interface ...

Page 45: ...to change the password for the user maximum of 10 characters including digits and case sensitive letters See Fig 48 Click to delete a user After deleting a user all data of the user will be deleted See Fig 49 Add Add a new user name See Fig 50 2 2 5 2 Change user Per Fig 44 click the Switch user icon to switch to a different user account ...

Page 46: ...46 Fig 51 Change interface 2 2 5 SWITCH button function Fig 52 SWITCH button ...

Page 47: ...rewdriver large medium small small tweezers clean gauze clean cotton swabs clean brush rubber gloves 75 alcohol and cleaning fluid etc 2 Daily maintenance Daily maintenance is recommended after daily use The specific operation steps are as follows 1 After daily use is completed power off the instrument and remove the samples reagents and consumables from the platform 2 Properly dispose of any used...

Page 48: ...ck that all the moving parts are not making any abnormal noises and that all screws are tight If any screws have become loose please tighten them 4 Annual maintenance Contact the Accuris Instruments your authorized distributor or authorized service provider for any necessary maintenance including but not limited to the following items 1 Check that the moving platform is level and operating smoothl...

Page 49: ...pt Motor failure 4 Abnormal sound during operation Guide rail problem Contact distributor or Accuris Service Dept Motor failure Gears or screw drive is worn or damaged 5 SWITCH button not working Button failure Contact distributor or Accuris Service Dept 6 Pipetting is not accurate Calibration required Contact distributor or Accuris Service Dept 7 The pipetting head not positioning correctly durin...

Page 50: ... Steps lost E134 Z axis Failed to leave zero E413 Failed to return zero E403 Memory is damaged E713 Motor data is lost E723 Motor data error E733 Calibration data is lost E743 Calibration data error E753 Movement module Over temperature pre warning E109 Over temperature E119 Short circuit in motor E107 Memory is damaged E713 Motor data is lost E723 Motor data error E733 Calibration data is lost E7...

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