3
Changing the mode of operation
3.1 Changing the Mode of Operation
This chapter describes how to prepare the mass spectrometer for the following modes of
operation:
• ESI (electrospray ionization)
• ESCi (combined electrospray and atmospheric pressure chemical ionization)
• APCI (atmospheric pressure chemical ionization)
• Combined atmospheric pressure photoionization (APPI/APCI)
• Low flow ESI
• UniSpray
• NanoFlow ESI
• ionKey source
For details about other Waters and third-party source options, refer to the documentation supplied
with the source.
3.2 ESI, ESCi, and APCI modes
ESI, ESCi, and APCI modes are all configured using a standard source enclosure.
3.2.1 ESI mode
To operate in ESI mode, you must fit the ESI probe adaptor to the source enclosure, and install a
probe assembly.
The ESI probe adaptor fitted with a standard ESI probe assembly accommodates eluent flow
rates as fast as 2 mL/min.
.
June 9, 2016, 715004990 Rev. A
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