Waters Xevo G2 QTof, Operator'S, Overview And Maintenance Manual, Page: 65 / 248

Overview of the NanoLockSpray source 4-3
Schematic of the NanoLockSpray source:
Spray indexing permits acquiring sample and lock-spray data in separate
data channels, and the baffle design ensures negligible cross talk between the
two sprays. Data from the lock-spray are used to calculate a correction factor
for the mass scale calibration, which is then applied to the sample data to
provide exact mass information.
Sample sprayer
The NanoLockSpray source can be used with different NanoFlow sprayers.
For sprayer-specific instructions on how to set up these sprayers, see page 4-4 .
Lock-spray sprayer
The lock-spray sprayer runs from the instrument's IntelliStart Fluidics
system. Fitted with a 500-µL pump, the lock spray operates at 0.5 µL/min.
You must choose a concentration for the lock-spray solution that produces a
suitable ion intensity.
For maintenance information, see
page 5-85 .
Sample inlet
Sample cone
Lock-spray inlet
Baffle