Waters Xevo G2 QTof, Operator'S, Overview And Maintenance Manual, Page: 25 / 248

LockSpray source and ionization modes 1-7
Xevo G2 QTof fitted with LockSpray source:
Electrospray ionization (ESI)
In electrospray ionization (ESI), a strong electrical charge is applied to the
eluent as it emerges from a nebulizer. The droplets that compose the resultant
aerosol undergo a reduction in size (solvent evaporation). As solvent continues
to evaporate, the charge density increases until the droplet surfaces eject ions
(ion evaporation). The ions can be singly or multiply charged.
To operate the LockSpray source in ESI mode, you fit the source enclosure
with an ESI probe.