Waters SYNAPT G2, Operator'S, Overview And Maintenance Manual

Page: 27 / 236

IntelliStart Fluidics system 1-9
Dual-mode ionization source
Atmospheric pressure photoionization (APPI) uses photons generated by a
discharge UV lamp (~10.2 eV) to produce sample ions from vaporized LC
eluent. Direct photoionization of the sample molecule occurs when the photon
energy exceeds the ionization potential of the sample molecule.
The optional dual-mode (APPI/APCI) ionization source incorporates an APPI
source enclosure used in conjunction with a standard APCI probe. You can
operate the source in APPI, APCI, or dual-mode, which switches rapidly
between ionization modes, facilitating high-throughput analyses.
See also:
The Waters SYNAPT G2 Dual-mode Ionization Source Operator’s
Guide .
Matrix-assisted laser desorption ionization
The matrix-assisted laser desorption ionization (MALDI) interface enables
rapid, tool-free switching between API and MALDI modes. A motorized stage
moves the MALDI source into position.
See also:
The Waters MALDI SYNAPT G2 MS System Operator’s Guide .
IntelliStart Fluidics system
Overview
The IntelliStart Fluidics system is built into the instrument; it controls how
sample is delivered to the source.
For standard flow applications, the system delivers sample directly to the
mass spectrometer source in one of three ways:
• From the LC column.
• From three integral vials.
Tip:
The vials can also deliver sample through direct or combined
infusion to enable optimization at analytical flow rates.
• From a wash reservoir that contains solvent for flushing the
instrument’s solvent delivery system.