Waters Micromass ZQ 2000, Operator'S Manual, Page: 108 / 133

Using the ESCi Multi-Mode Ionization Source 108
A
Appendix A
Using the ESCi Multi-Mode
Ionization Source
When fitted with the ESCi™ Multi-Mode Ionization Source, the Waters
®
Micromass
®
ZQ™
Mass Detector alternates between acquiring data in ESI and APCI ionization modes within
the same run. This software-mediated capability depends on a high voltage power supply,
which in ESCi mode switches continuously between supplying voltage to the ESI capillary
and current to the APCI corona needle. Scanning occurs with the ESI probe installed and
interscan delay times as short as 100 msec. The operating software, MassLynx™ version
4.0, lets you select ionization modes and polarities in varying combinations and durations.
A.1 Preparing for Operation
Preparing the ZQ Detector for ESCi operation entails these activities:
• Installing the corona discharge needle
• Setting up the MassLynx software
• Performing the Daidzein test
A.1.1 Installing the Corona Discharge Needle
If you have been operating the instrument in ESI mode, you must install the corona
discharge needle in the instrument’s source. (If you have been operating it in APCI mode,
the corona needle should be installed already.)
1. Remove the center panel from the front of the instrument, grasping its sides and
pulling it toward you (
Figure A-1 ).