B
Solvent considerations
Warning:
Observe Good Laboratory Practice (GLP) at all times, particularly when
working with hazardous materials. Consult the Material Safety Data Sheets regarding
the solvents you use. Additionally, consult the safety representative for your
organization regarding its protocols for handling such materials.
The information in this appendix applies only to the following instruments:
• ACQUITY UPLC H-Class system modules
• ACQUITY UPLC PDA detector
• ACQUITY UPLC PDA eλ detector
• ACQUITY UPLC PDA-TS detector
• ACQUITY UPLC TUV detector
• ACQUITY UPLC ELS detector
• ACQUITY UPLC FLR detector
• 2432 Conductivity detector
B.1 Solvent recommendations
The system is designed for reversed-phase chromatography and ACQUITY UPLC BEH column
chemistries. Waters evaluated the system’s reliability using traditional reversed-phase solvents.
Notes:
• When implementing passive check valves on ACQUITY systems, Waters recommends that
you use MS Grade solvents.
• You can use some normal-phase solvents on the system if you make the appropriate
modifications. See
and
This section lists solvents recommended for the system. Contact Waters Customer Service to
determine whether you can use solvents that do not appear in the list without adversely affecting
instrument or system performance.
August 8, 2016, 715005049 Rev. C
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