WATERS CORPORATION TQ, Operator'S Manual, Page: 52 / 192

3 ESI Operation
52 December 6, 2012, 71500126802IVD Rev. C
Removing the ESI probe
Required material:
Chemical-resistant, powder-free gloves
To remove the ESI probe
1. Prepare the instrument for working on the source (see page 59 ).
2. Open the instrument’s access door.
3. Disconnect the diverter valve tubing from the ESI probe.
4. Disconnect the ESI probe’s electrical lead from the high voltage
connection.
5. Ensure that the API gas is turned off.
6. Disconnect the ESI probe’s PTFE tube from the nebulizer gas
connection.
7. Undo the 2 thumbscrews securing the ESI probe to the probe adjuster
assembly.
8. Carefully remove the ESI probe from the probe adjuster assembly.
9. If available, fit the protective sleeve to the ESI probe tip.
10. Close the instrument’s access door.
Warning:
The ACQUITY UPLC system connections, ESI probe,
and source can be contaminated with biohazardous and/or toxic
materials. Always wear chemical-resistant, powder-free gloves
while performing this procedure.
Warning:
To avoid electric shock, ensure that the instrument is
suitably prepared before commencing this procedure.
Warning:
The ESI probe and source can be hot. To avoid burn
injuries, take great care while working with the instrument’s
access door open.
Warning:
The ESI probe tip is sharp. To avoid puncture wounds,
handle the probe with care.