ThermoFisher Scientific Vanquish VC-D50, Operating Manual

Page: 64 / 188

5 • Installation
Page 64 Fluorescence Detectors (VC-D50, VC-D51, VF-D50, VF-D51)
Operating Manual
5.6 Setting Up the Flow Connections
5.6.1 General Information and Guidelines
When setting up flow connections, follow these rules and
recommendations:
Flow connections can be filled with hazardous substances. Observe the
warning messages and precautionary statements presented in
Safety
Precautions ( } page 21) .
NOTICE
Particulate matter from other system modules and components can
deposit in the flow cell and clog it.
• Before you connect the flow cell to the flow path, make sure that
you thoroughly flush the modules in the system flow path upstream
of the device to waste.
• When you install devices or components to the system, always flush
them to waste before connecting them in the system flow path. To
flush the Vanquish modules, follow the instructions in the
Vanquish
System Operating Manual .
NOTICE
Flow cells are highly sensitive to contamination, clogging and high
backpressures. Even if the pressure exceeds the upper limit for a very
short time only, the flow cell may be permanently damaged. Observe
the following notes when connecting the flow cell to the system flow
path:
• When connecting a component in the flow path after the flow cell,
observe the specified backpressure for the flow cell.
• Use only clean Viper capillaries which were provided for the flow cell
and which have been properly protected by their cap before.
• Use only the waste line which was provided for the flow cell.
• Avoid clogging of the flow cell or waste line.
• Improperly set up flow connections can lead to leaks on the flow cell
or even destroy the flow cell. Do not invert the flow cell inlet and
outlet.