Thermo Scientific thermoscientific Vanquish Pumps C, Operating Manual

Page: 108 / 296

6 • Operation
Page 108 Pumps C, Pumps F ( VC-Pxx, VF-Pxx)
Operating Manual
6.8.2.2 Purging for Removing Air Bubbles or Changing to Different Solvent Type
• To remove air bubbles that might be trapped in the system (pump
head, solvent lines) because air bubbles in the system may lead to
the following problems:
¨
Pressure pulsation
¨
High noise level or pulsation during pump operation
¨
Non-reproducible analysis
• When changing to a different type of solvent, for example, when
changing to a different analytical method
TIP When the pump is operated for the first time or when solvent lines
are empty, follow the steps in Purging with First Time Operation or
Empty Solvent Lines ( } page 105) .
Items required
• Solvents suitable for purging
• Silicone tubing
• Tissue
Preparations
1. To be able to generate negative pressure, connect an autosampler
or another type of flow restriction to the pump outlet. If necessary,
close the pump outlet with a fitting plug.
2. On the purge/sensor unit, attach silicone tubing to the purge outlet
(if it is not yet connected).
3. Route the free end of the tubing to the drain port outlet (see
Guiding Liquids to Waste ( } page 64) ).
4. Open the purge valve by turning the valve knob counterclockwise.
Follow these steps
1. In the Chromeleon software, set the channel that you want to purge
to 100%.
2. Optional: In the Chromeleon software, adapt the settings for the
purge flow or purge time if required.
3. Binary pump and dual pump: For purging from the keypad, verify
that you have selected the pump head (pump) for which you want to
perform the procedure.