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Functional Description
Reference Inlet System
Thermo Scientific
Surveyor MSQ Plus Hardware Manual
17
The software applies these adjustments to all subsequent acquisitions until you perform a new
Full System Autotune or Mass Scale Calibration.
After installing the Surveyor MSQ Plus MS detector, a Thermo Fisher Scientific service
engineer performs a Full System Autotune. You must repeat the procedure if you move the
MS detector to a new location, install or update the Xcalibur data system, or the environment
of your laboratory changes. If you notice a drift in the mass accuracy of your analyses, you
should perform a Mass Scale Calibration.
The reference inlet system consists of a reference inlet reservoir, a waste reservoirs nitrogen
pressurization line, a PEEK delivery tube, and a Rheodyne microinjection (switching) valve.
One end of the PEEK tubing is inserted into the reference reservoir and the other end of the
tubing is attached to port 5 of the Rheodyne microinjection valve.
Pressuring the reference reservoir with nitrogen gas and switching the valve to the load
position forces the calibrant solution through the tubing into a 500
μ
L sample loop as shown
in
. After the sample loop is filled, the valve switches to the inject position, allowing
mobile phase to push the calibrant out of the sample loop and through the API probe as
shown in
.
Note
Perform a mass calibration by selecting either the Full System Autotune or the
Mass Scale Calibration option from the Instrument Tuning and Calibration wizard.
CAUTION
The union that connects the Rheodyne microinjection (switching) valve to the
API probe is a grounding union. Do
not
connect port 3 of the Rheodyne microinjection
directly to the inlet of the API probe. Bypassing the grounding union could lead to
instrument damage and personal injury.
