Thermo Scientific 074114, Operator'S Manual

Page: 35 / 148

2 • Description
Doc. 065378-01 1/12
27
To clean the pump and system between applications:
1. Remove the column and the suppressor (if installed).
2. Connect the line exiting the injection valve directly to the flow cell
inlet tubing.
3. Flush the system with deionized water at 1.0 mL/min for 20 minutes.
4. Flush the system with methanol at 1.0 mL/min for 20 minutes. For
very sensitive applications, continue flushing for several hours.
5. Flush the system with deionized water at 1.0 mL/min for 15 to
20 minutes.
6. Reinstall the column (and the suppressor, if removed) and equilibrate
the system before resuming operation.
2.7 Chromatography Software
2.7.1 Overview
The Dionex PDA is controlled by a PC configured with either the
Chromeleon 7 Chromatography Data System or the Chromeleon 6.8
Chromatography Data System. Both software products provide extensive
instrument control, data management, reporting, and compliance features.
In Chromeleon 7, an ePanel Set provides centralized system control. You
can use the ePanel Set to view system status information and issue
commands for controlling each module. In Chromeleon 6.8, these
functions are available on a
panel tabset .
In both the ePanel Set and the panel tabset, a convenient Home panel
shows the overall system status and provides basic module control
If there is a heavy salt build-up on the pump pistons, remove the
pistons and clean them with deionized water. Refer to the pump user’s
manual for instructions. (Cleaning the pistons removes salt crystals
that can abrade the piston, thereby causing the main seal to wear out
prematurely and allow leaks.)
Replace the piston seals if there is a heavy salt build-up on the
pistons, if the seals leak, or if the pistons are replaced. Refer to the
pump user’s manual for instructions.