TA Instruments Nano ITC Series, Getting Started Manual

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Page 14 Nano ITC Getting Started Guide
Syringe/Stirrer
Nano ITC Standard Volume systems include two syringes of 100 and 250 µL capacities. Two buret
syringes are provided with 100 µL and 250 µL capacities. The only difference in dimension between the
two is the inner diameter of the syringe barrel; the needles are identical in order to maintain the thermal
and mechanical properties.
The Nano ITC Low Volume system includes one 50-µL syringe. This syringe uses a shorter needle. To
avoid possible damage, do not use the larger syringes with the Low Volume ITC. If you feel a stiff resis-
tance or if the buret handle does not readily slip fully into place in the ITC, do not force it. Remove the
buret and check to see if the correct size syringe is installed. You can verify the feel of the normal
resistance by installing a buret with no syringe in place.
The titrant syringe needle also functions as the stirrer and extends down into the reaction vessel from the
top when the buret is mounted. The needle is balanced for optimum stirring efficiency. It has two Teflon
bushings to help dampen stirring noise and ensure that the needle spins true within the cell access tube (see
the figure below).
Figure 6 Orientation of buret, syringe, needles, and cells during experiments.
CAUTION: To avoid possible damage, do not use the 100 or 250 µL syringes with the Nano ITC
Low Volume instrument. Syringes are shipped with warning labels which may, if desired, be
affixed to the ITC by the customer to serve as a reminder.
Plunger position
indicator
Buret handle
Syringe plunger
Rotating buret
shaft
Graduated
syringe barrel
Knurled syringe
mounting knob
Reference cell
with reference
needle
Sample cell
with syringe
needle/stirrer