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Siemens ADVIA 1800 Operator'S Manual Download Page 109

Quality Control 

109 

4 Quality Control 

Quality control overview 

When to run control samples 

Refer to the ADVIA Chemistry system methods documentation for the quality control 
recommendations. 

Setting up quality control 

•

 

Use the QC Sample Definition window to define each of the 26 controls that can 
reside on the calibrator/control tray (CTT). 

•

 

Use the Control Data Setup window to enter the control average and standard 
deviation (SD) data for each control. 

Running the control samples 

•

 

Use the Start Conditions window to request control samples. You can run control 
samples alone, after calibration, or before patient samples. You can request to run 
only specific control samples or selected methods. 

•

 

The Ordinary control samp. meas. list on the Test Select window determines which 
tests are available to run. The Sample Select window determines which controls are 
available. 

•

 

Use the QC Sample Definition window to automatically run controls after a specified 
number of assays. 

•

 

The Auto control samp. meas. list on the Test Select window determines which tests 
are available to run. The Sample Select window determines which controls are 
available. 

Summary of Contents for ADVIA 1800

Page 1: ...11221680 Rev A 2015 12 Operator s Guide ADVIA 1800 Chemistry System ADVIA 1800 Chemistr y System ...

Page 2: ...d Observe all warning and hazard statements The ADVIA Chemistry system is manufactured in Japan for Siemens The Universal Rack Handling System is manufactured in Germany for Siemens Manufactured in Japan for Copyright and trademarks ADVIA Centaur and ADVIA are trademarks of Siemens Healthcare Diagnostics Acrobat is a trademark of Adobe Systems Incorporated Clorox is a trademark of The Clorox Compa...

Page 3: ... front view 18 PC back view 19 Opening the Top Cover 19 Reagents 19 Reagent mechanisms 19 Reagent trays 20 Reagent tray operation 20 RGT Pause button 21 Reagent pumps 21 Reagent container types 22 Sampling and analysis of photometric tests 22 Sample aspiration 22 Sample tray 22 SMP Pause 23 Sample aspiration and dilution mechanisms 24 Dilution pumps DIP and DOP 24 Sample pumps 25 Sample dilution 2...

Page 4: ...us and message boxes 39 Other tasks accessed from System s on the Operation Panel 39 Menu Panel 40 Other tasks accessed from System s on the Menu Panel 40 Description of software windows 41 Request windows 41 Order Entry window 41 Sample Log window 42 Test Result Monitor window 42 Sample test status color codes 43 Review Edit window 44 Reaction Monitor window 45 RealTime Monitor window 45 Test Sel...

Page 5: ... of messages listed 52 Updating the message list 52 Printing the messages 52 Deleting the messages 52 JEOL Maintenance window 52 Liquid Level Sensor Monitor window 53 LAS Monitor window 53 Test Utilization Statistics window 53 Reagent windows 53 Reagent Inventory window 53 Monitoring Reagent Positions number of Tests Volumes and Days Remaining 54 NOTES 54 Executing a Barcode Scan 55 Deselecting a ...

Page 6: ...al Sample Setup window 63 Setting System Parameters window 64 New Test Definition window 64 Analytical Parameters Chemistry window 64 Process Sequence window 66 Ratio Parameters window 66 Blank Reagent Settings window 66 Contamination Settings window 66 Online Settings window 67 Alarm Buzzer Settings window 67 User Code Settings window 67 Other Tasks 67 Version Information window 68 ADVIA o p 68 C...

Page 7: ...T 87 Starting the run 87 Running calibrators and reagent baselines RBL 87 Running control samples 88 Monitoring samples loaded on the optional universal rack handler 89 Running an interrupt STAT sample 89 Monitoring an analysis while it is running 90 Processing status 90 Sample information and system status 90 Result data information 91 Using the Sample Log 91 Viewing the sample log entries 91 Sea...

Page 8: ...ibration 100 Using multiple reagent containers for the same test 100 Auto calibration and auto QC Situations that need corrective steps 101 Auto calibration with system related errors 101 Auto calibration with lot change 101 Reagent pack switch in mid calibration 101 3 Calibration 103 Calibration overview 103 When to calibrate 103 Setting up the calibration 103 Entering absolute or single point ST...

Page 9: ...h 131 Checking and replenishing the lamp coolant 132 Checking lamp energy 133 Reading lamp energy data 135 Measuring cuvette blanks 135 Cell blank measurement results are summarized as follows 136 Cleaning the analyzer and rack handler exterior panels 137 Monthly maintenance 138 Cleaning the turntable interiors STT CTT and RTT 138 Cleaning the inside of the STT CTT housing 138 Cleaning the inside ...

Page 10: ...th oil bottle 166 Preventive cleaning of the wash station lines 168 Washing all the ISE lines 172 Washing the lines 173 Rinsing the lines 173 Priming and initializing the ISE module 174 Replacing ISE electrodes 174 Removing electrodes 174 Installing electrodes 175 Priming the ISEs 175 Calibrating the ISEs 176 Storing the reference electrode 176 Conditioning the Na and K electrodes 177 Cleaning the...

Page 11: ...e rerun automatically 193 Manually requesting rerun using Review Edit 193 Appendix A Safety Information 195 Warning and hazard statements 195 Biohazard warning 195 Electrical warning 195 Laser warning 195 Household bleach warning 196 Ancillary and method reagents warnings 196 Regulatory compliance 197 Laser information 197 Appendix B Warranty and Support Information 199 Limited Instrument Warranty...

Page 12: ...pecifications all 207 Appendix E Symbols 213 Explanations of symbols associated with the ADVIA 1800 system 213 Warning and caution symbols 213 System operation symbols 214 System rating label symbols 215 Hardware component symbols 216 Ancillary reagent symbols 216 Connector symbols 217 System packaging label symbols 218 Appendix F Flags 219 Alarm result flags 219 ...

Page 13: ...n the sample tray or rack handler are aspirated and diluted by the dilution probe then dispensed into cuvettes in the dilution tray 4 The dilution mixer stirs the diluted sample 5 The sample probe dispenses the required amount of diluted sample into the RRV cuvettes the reagent is already in the cuvettes The system can use the remaining diluted sample in the DTT cuvettes for additional tests on a ...

Page 14: ...he lamp energy is checked at each wavelength Hardware Overview 1 ISE Buffer Solution 2 Incubation Bath Oil 3 Isotonic Saline Diluent 4 Cuvette Wash Solution 5 Cuvette Conditioner 6 Pure water Bottle 7 Reaction Bath Oil Pump 8 LWP Pressure Meter 9 Power and Display Panel 10 LWP Inline Filter 11 Level Sensor Connectors 12 Pumps behind reagent bottles Figure 1 2 Analyzer front view ...

Page 15: ...NG If the system was stopped using the Emergency Stop button you must perform a Weekly wash WASH2 prior to processing samples 6 OPERATE STANDBY switch turns the analyzer power ON OPERATE or OFF STANDBY 7 POWER lamp lights when the analyzer power is ON Analyzer back view 1 Printer Power Cord to separate power source 2 PC Power Cord 3 Monitor Power Cord 4 Main Power Switch powers the entire instrume...

Page 16: ...e Dilution Probe DPP 3 Dilution Mixer DMIX 4 Dilution Tray DTT 5 Dilution Washer DWUD 6 Sample Probe SPP 7 Reaction Tray washer WUD 8 Reaction Tray RRV 9 Reaction Mixer 2 MIXR2 10 Reagent Probe 2 RPP2 11 Reagent Tray 2 RTT2 12 Reagent Probe 1 RPP1 13 Reagent Tray 1 RTT1 14 Reaction Mixer 1 MIXR1 15 Spectrophotometer Compartment lid off 16 Sample Rotate and Sample Pause Buttons Figure 1 5 Analyzer ...

Page 17: ...use buttons 1 STT Rotation Button 2 LED 3 SMP Pause Button Pumps 1 Sampling Pump SP 2 Dilution Aspiration Pump DIP 3 Dilution Discharge Pump DOP 4 Dilution Wash Pump DCP 5 Sampling and reagent wash pump SRWP 6 Reagent Dispensing Pump 1 RP1 7 Reagent Dispensing Pump 2 RP2 Figure 1 7 Vertical pumps ...

Page 18: ...sed to turn the power for the personal computer ON or OFF Normally it is left ON 3 DVD RW Drive 4 DVD RW drive access lamp Lights when reading the CD 5 Eject CD 6 DVD ROM drive eject button Press to remove the CD 7 PC power lamp Lights when the power for the personal computer is ON 8 Hard drive access lamp Lights when reading or writing to the hard disk 9 Reset Switch 10 Access Door Figure 1 9 PC ...

Page 19: ...pen Failure to do so could cause unexpected closure of the cover resulting in injury To open the top cover perform the following steps 1 Open the top cover 2 Confirm that the cover is in the full open position The top cover is in the full open position when it comes to a hard stop and cannot be raised any further Reagents Reagent mechanisms The reagent probes RPP1 and RPP2 aspirate reagent from th...

Page 20: ...agent R1 RTT2 contains the second reagent R2 You can use any reagent container for more than one test item a test item may require more than one reagent container Each reagent tray has a barcode reader RBC 1 and RBC 2 Reagent tray operation At initialization the trays rotate clockwise until reagent bottle 1 is in the aspiration position After you start a run the reagent trays move clockwise to pos...

Page 21: ...quality check or any deviation from approved procedures may override a pause Failure to monitor operating mode messages and avoid moving parts may result in injury NOTES The text on the RGT Pause button is gray when inactive and black when active After the button is selected the RGT Pause process can take some time The system will safely complete any tests on samples that have been aspirated For m...

Page 22: ...ttings window in the reagent trays The trays can hold 20 mL 40 mL or 70 mL wedge shaped containers At this window you also specify the reagent type R1 or R2 for each reagent container Barcode labels on reagent containers have the test name expiration date lot number and container ID number You can initiate a barcode scan at the Reagent Inventory window Sampling and analysis of photometric tests Sa...

Page 23: ...e button does not elicit an immediate response An automated quality check or any deviation from approved procedures may override a pause Failure to monitor operating mode messages and avoid moving parts may result in injury NOTES The text on the SMP Pause button located on the Operation Panel is gray when inactive and black when active When the button is gray on the Operation Panel the button on t...

Page 24: ...charge Pump DOP 3 Dilution Probe Wash Pump DCP Figure 1 16 Dilution pumps The aspiration pump DIP withdraws sample from the sample tray or from an automatic laboratory system such as a rack handler or lab cell the discharge DOP pump dispenses sample into the DTT cuvettes The DPP executes both actions During both actions the dilution pump valves DPEV1 and DPEV2 are closed After the sample is aspira...

Page 25: ...ilution Dilution tray operation At the time of system initialization the tray rotates clockwise until DTT cuvette 1 is in the aspiration position During sampling the DTT rotates clockwise or counterclockwise depending on which rotation is smaller For each sample it performs these actions in a 3 second cycle Moves cuvette to mixer position after sample is dispensed into DTT cuvette Moves cuvette to...

Page 26: ...ed with deionized water During this period the dilution mixer wash valve DMEV is open and briefly the mixer rod is on The mixer is raised and moved to the mixer position where it is lowered into the DTT cuvette The rod is turned on to mix the sample The mixer is raised from the cuvette and moved back to the wash port The next cycle begins If an assay is not running you can operate the unit manuall...

Page 27: ... to prescreen samples for clots Partial DPP obstructions are not detected The system monitors the pressure at the transducer at four points during the sampling cycle and displays an error if a predefined limit is exceeded at any of the checkpoints A fifth check occurs at the start of sampling You can toggle clot detection on and off You can deactivate clot detection for calibrator and control mate...

Page 28: ...ction tray At initialization the SPP moves in the up position to the RRV cuvette then stops above the wash port The pumps stop when the SPP is over the RRV cuvettes Each sampling cycle consists of these steps 1 The SPP moves to the aspiration position of the DTT and aspirates the sample 2 The SPP moves back to the wash port where deionized water washes the SPP s outside surface 3 The SPP moves to ...

Page 29: ...d the reagent probes RPP1 and RPP2 the SPP does not have liquid level sensing This is because the software is able to calculate the volume of liquid in a DTT cuvette Analysis Reaction tray 1 Reaction Tray RRV 2 RRV Cuvettes immersed in oil heat bath Figure 1 21 Reaction tray For each sample assay the reagent probes RPP1 and RPP2 dispense reagent into cuvettes in the reaction tray RRV Then the samp...

Page 30: ...tte 5 After three seconds the cuvette moves another half turn to the mixer 1 MIXR1 position The second cuvette moves to the sample dispense position and an empty cuvette moves to the R1 dispense position three positions from MIXR1 During each half turn the spectrophotometer measures the absorbance of the liquid in each of the cuvettes that pass it across all 14 wavelengths 6 MIXR1 mixes the reagen...

Page 31: ...ions then go to the down position If a mixer is already at the mixer position it is raised then lowered During each half turn on the RRV the following steps occur this sequence applies to each mixer the mixers used depend on the analysis conditions 1 The mixer moves up and over to the wash port where it is washed with deionized water During this period the reaction tray mixer wash valve MWEV1 or M...

Page 32: ...one nozzle it moves to the next until washing is complete While the RRV rotates the WUD is in the up position The wash liquids pass through a preheater before they reach the WUD Figure 1 23 Reaction tray wash mechanisms Reaction washer operation At initialization the WUD moves to the up position If it is already up it is lowered then raised To advance the cuvettes to the next wash nozzle the RRV r...

Page 33: ...nditions 3 E Aspirates detergent B2 Dispenses wash water H3 Absorbs overflow liquid in abnormal conditions 4 C2 Aspirates wash water F Dispenses cell conditioner H4 Absorbs overflow liquid in abnormal conditions 5 G Aspirates cell conditioner B3 Dispenses wash water H5 Absorbs overflow liquid in abnormal conditions 6 C3 Aspirates wash water 7 I Vacuums remaining liquid from cuvette Figure 1 24 Noz...

Page 34: ...res the amount of light absorbed at 14 specific wavelengths by liquids contained in reaction cuvettes Every six seconds the reaction tray RRV moves cuvettes containing reaction liquid sample and reagent in front of a halogen lamp which sends light through the cuvettes Each time a different wavelength is measured The photometer then measures the absorbance based on the lamp energy and the optical d...

Page 35: ...ophotometer ISE electrolyte analyzer The ISE measures the amount of sodium Na potassium K and chloride Cl in serum or urine samples through voltage measurement by ion selective electrodes The sample dilution probe DPP aspirates the sample for electrolyte analysis The electrolyte analysis uses buffer as reagents In a two stage process the buffer voltage is measured then the sample voltage is measur...

Page 36: ...nal The universal rack handler is a separate sample delivery mechanism designed to allow operators to continuously load samples The operator can load five sample containers into each rack and up to fifteen racks 75 samples on each rack carrier to improve workflow efficiency The sample dilution probe DPP aspirates the sample on the rack handler just as it does from the sample tray from an aspiratio...

Page 37: ... Main PCB Chassis 5 Cross Drive 6 Conveyor 3 7 Sampling Station LS2 8 Outfeed Buffer 9 Outfeed Pusher 10 READY STANDBY Switch 11 Infeed Pusher Arm 12 Infeed Tray 13 Display Panel 14 Rack load Status Indicator 15 Outfeed Tray Figure 1 28 Universal rack handler components ...

Page 38: ...ong as the software is running these windows remain in the same position unlike most Windows XP windows Use the top display option Systems s to allow other windows to display on top of the Menu Panel and Operation Panel Startup window The Startup window is the first window you see when you turn on the PC and the last window when you stop the system Perform any of the following tasks at this window...

Page 39: ...Start RGT Pause Wash Initialize Stop SMP Pause Prime Host On Off Error log Audible Alarm Operator s Guide Status and message boxes The boxes on the right of the Operation Panel provide information on current system conditions 1 Operating modes 3 Alarm message box 2 Load status indicator 4 Time remaining indicator 5 Siemens Remote Services SRS indicator Other tasks accessed from System s on the Ope...

Page 40: ...ervisor or tech_manager when you start the system you are automatically logged in as a user If you are already logged in as supervisor or tech_manager you can log back in as a user 1 At the System S menu select Password 2 Enter the new user name access level and the corresponding password Or do not type a password at the Password window to log in as a user 3 Select OK You are now logged in as the ...

Page 41: ...m S menu select Change User 2 In the Please enter password box enter the user password User passwords assigned in the User Code Settings window are not case sensitive 3 Select OK You are now logged in as the new user Exiting the system Use this procedure to close the system software 1 At the System S menu select Exit x 2 When prompted select Yes then select Yes when prompted again In a few seconds...

Page 42: ...ach sample log entry Asp Date and Time External Type STT Sample Id Rerun CTT Description Results search the sample log delete a specific sample log entry delete all sample log entries print a list of the sample log entries export the sample log entries Test Result Monitor window Use this window to monitor an analysis while it is running At the Test Result Monitor window you can monitor the followi...

Page 43: ...number does not contain a sample for this run Untested gray The run began and a workorder was created for this sample but the sample was not yet aspirated from the sample tray In process pink At the Test Result Monitor window the sample was aspirated from the sample tray and was added to the dilution tray At the Review Edit window the sample is being analyzed or is being rerun Complete blue At the...

Page 44: ...ult Monitor window displays three panels The System Status panel shows the current operating mode of the system The Sample information panel shows the sample number and sample position of the currently selected position on the STT CTT graphic If this is a barcode analysis the barcode number displays and the position number is 0 00 The code panel shows the color codes used in the STT CTT graphic to...

Page 45: ...Select window You select tests in this window for patient and control sample analysis and calibrations Use this window for the following tasks Disable down a test For example a test may be downloaded from a host system to analyzers in your lab but that test is not run on the ADVIA Chemistry System To down a test select one of the Test Select radio buttons and deselect it from the corresponding tes...

Page 46: ... PDF from the LRC 1 At the Menu Panel select Request then select RealTime Monitor NOTE You can view and print data only after all results for a sample are completed At the RealTime Monitor window the latest tests display in the window on the left 2 Select the Date to display a test with a different date to monitor 3 Select a Sample from the list to display the specific data for a selected test Eac...

Page 47: ...s in the Data Transmit window The default settings are restored when you exit and re enter the window Calibration windows Select Calibration to display the following Calibration menu View Calibration Curve window Use the View Calibration Curve window to review the detailed calibration curve data for a method to restore a calibration to monitor calibration trends to obtain a summary of all calibrat...

Page 48: ...required to calibrate each photometric test You can request automatic recalibration for each test whenever a new reagent container is loaded or after a user specified time interval When a time interval expires the system recalibrates at the start of the next run NOTE You can run tests with 2 different lots of the same reagent but you cannot calibrate the 2 lots on the system at the same time You h...

Page 49: ...easurement cell blank measurement batch printing filing of measurement data save of text file System Monitor window Perform any of the following tasks at this window verify operating conditions daily procedures set the system monitor system settings System Maintenance Monitor window Perform any of the following tasks at this window enter schedules for maintenance tasks monitor the maintenance stat...

Page 50: ...y graphs monitor serum or urine calibrations monitor calibration trace data display data from past calibrations monitor selectivity check data print the results delete calibration trace data change y axis scale The selectivity check must be performed under the supervision of authorized Siemens service personnel Please call your local technical support provider or distributor Manual Operation windo...

Page 51: ...e buzzer On Line Monitor window Use this window to monitor the exchange of data between the system and the host computer The monitor displays the data being exchanged and the control signal codes that ensure accurate transmission of information You can view up to 300 data items in the window Error Report window Use the Error Report window to review system status and error messages If the column ha...

Page 52: ...ific message the additional information may contain possible causes and recommended corrective action 2 Close the window Controlling the number of messages listed 1 In the Disp switch area select Standard or Extend 2 In the Scope area select Today or All Updating the message list Select Latest info to place the most current message on the first line of the list Printing the messages 1 Select Print...

Page 53: ...trument to the external interface WS displays communication from the workstation to the external interface NOTE You can resize the column displays in the LAS Monitor window When you exit out of the window and return again the default settings are restored Test Utilization Statistics window Use this window to monitor the test utilization against Patient Calibrations and Controls NOTE All tests defi...

Page 54: ...ate is entered The Cal Interval Days is the number of days remaining to the end of the calibration interval When you place a reagent with a new lot number on the system the Cal Interval Days column defaults to the letter C This indicates that you must run calibration on the new reagent After calibrating the new reagent the number in the Cal Interval Days column resets to the maximum calibration in...

Page 55: ...e Days Remaining is the number of days remaining until the end of on system stability for a method Executing a Barcode Scan 1 Check that the analyzer is in READY mode and that the barcode reader is turned on 2 Select Barcode Scan 3 The Read the Reagent Barcode message displays 4 To execute a barcode scan select Yes The barcode readers on RTT1 and RTT2 scan all positions for each reagent tray and s...

Page 56: ...e R1a 20 tests R1b 5 tests R1c 10 tests 35 remaining R2a 5 tests R2b 10 tests R2c 10 tests 25 remaining Total Tests 20 tests remaining 2 To print the Total Test Summary select Print 3 To close the Total Test Summary select Exit Viewing Cal Interval Review Use the Cal Interval Review list to review daily which methods you should calibrate NOTE For barcoded reagents this information is preset to Sie...

Page 57: ... window displays all tests loaded on the system but the deactivated or unchecked tests are grayed out NOTE At the Active Test List window you must select all the tests you expect to run If a test is not selected the system skips that test An error message does not display in the Alarm message box on the Operation Panel but is recorded in the error message log Active is checked if the test is activ...

Page 58: ...nd Date Opened on System information for one or more reagents displays when a Reagent Code is selected Perform any of the following tasks at this window clear all clear reagent code s clear reagent barcode s clear specific date clear range of dates QC windows Select the QC button to display the following QC menu ADVIA QC window ADVIA QC provides both real time and long term evaluation of analyzer ...

Page 59: ...the results starting from the first entry and adds new results after the latest entry The system does not display a message that the maximum number of results was reached Perform any of the following tasks at this window view the Levey Jennings charts x charts view the detailed control data information and omit invalid control results view the QC summary list view the daily QC list use daily stati...

Page 60: ...information copy control data registration information Sample Select window Use this window to select the samples for control sample analysis and calibrations and to temporarily disable a sample so that the rest of a run can proceed For example if you only want to run ISE calibration on serum samples disable the ISE calibration urine samples The run proceeds normally but it does not include urine ...

Page 61: ...ch are involved in creating workorders If the serum indices for each sample are not selected in the Order Entry window select one of these settings Request item range Compulsory item analysis Not handled Set the system monitor Set system parameters Basic system composition These settings allow you to customize general components of the system ISE Sample delivery Sample bar code On line Concentrate...

Page 62: ...est List window after initial setup If you reposition any tests on the System Test List window after initial setup results for samples already run could be associated with the wrong test name Perform any of the following tasks at this window add tests to list remove tests from list set the test processing order Analysis Order Set window Use this window to set the order in which tests on the list r...

Page 63: ...or edit a print form for sample results When you print reports from the Print Report or the Review Edit window you will select a print form created here There are two sample report formats provided A Patient Chart report Chart frm is formatted for a single sample A Consolidated report Consolid frm is formatted for multiple samples You create or edit each print form by placing design elements such ...

Page 64: ...can define new methods The system can store up to 200 chemistry methods in this window including predefined methods Methods 1 150 are predefined methods The analytical conditions are predefined Some of the fields of the analytical conditions are grayed out and cannot be edited Some of the parameters are disabled and are not editable by the User Supervisor Tech manager or FSE The Analytical Paramet...

Page 65: ...ettings in the analytical parameter fields the version number in the upper right corner of the window moves up one numerical increment and the date is updated to the current date for example from Ver 2 0 0 yyyymmdd to Ver 2 0 1 yyyymmdd in this example the 2 is the software version and the first 0 is the method parameter revision minor number In the Analy Cond No box choose a method or enter a new...

Page 66: ... items in each The ratio can contain 2 tests Blank Reagent Settings window You must log on as service to access this window Perform any of the following tasks at this window assign a blank channel use the calibration sample from one test for another test Contamination Settings window Use this window to set the conditions for preventing contamination of reagent probes and reaction tray cuvettes Eac...

Page 67: ... alarm buzzer for a status change print alarm buzzer settings delete alarm buzzer settings NOTE Please contact your local technical support provider or distributor before changing the default settings on this window User Code Settings window Use this window to enter a user code user name and user password for up to 50 operators who are authorized to use the chemistry system Perform any of the foll...

Page 68: ...of program Programs related to the overall system are in the System group Other programs are part of groups corresponding to their Menu Panel buttons for example Request Calib Process Brief description of the program s function often the name of the window it opens Version The version of the program being used in this version of the software does not have to match File name The name of the program...

Page 69: ...n of the file being used in this version of the software does not have to match Memo Use this window to write or display memos about the system At the Memo window you can do the following read a memo write or edit a memo print a memo clear a memo Using online help The online Operator s Guide viewer has three functional areas top navigation toolbar left navigation frame and right content frame Use ...

Page 70: ...e topics including reference documents and images appear in a second window Navigation from these windows including minimizing maximizing and closing use standard Windows conventions Some popups display partially outside the viewer content frame In this case to view the entire popup select and drag the lower right corner of the viewer window to enlarge it and view the complete popup Topics have hy...

Page 71: ...ens service personnel You are automatically logged on at the user level during startup No operator is required If you log on at the supervisor or tech_manager levels when done you should log on to the user level no password required Starting the system BIOHAZARD Before you turn on the system verify that waste drain is not clogged Clogging of the drain could result in a potential biohazard WARNINGS...

Page 72: ...ommunication to the PC is established 4 At the Startup window do the following a In the Please enter password box enter the user password User passwords assigned in the User Code Settings window are not case sensitive b Select New Start or Re start then select OK After a few minutes the Menu Panel and the Operation Panel open 5 When the Start and the Ready indicators are off and the Initialize but...

Page 73: ...lect Startup 6 In the Proc set list select the startup setting Set1 Set2 or Set3 you want to run 7 Select Start 8 To confirm select Yes The current operating mode displays in the System mode box and the time remaining to complete the startup displays in the Time until end box If a cell blank is run the system prompts you to save the results When done the system enters the Ready mode 9 To halt the ...

Page 74: ...e Flow rate of the heating bath fluid in mL minute A flow rate 2000 mL minute or 6000 mL minute is considered abnormal 3000 5000 mL min 3000 or 5000 mL min Fill the incubation bath oil bottle with more oil Adjust the flow regulator valve Make sure the bath oil is circulating properly in the constant temperature bath RRV Oil Level Status of the quantity of heating bath fluid Insufficient liquid is ...

Page 75: ...rs whether the tank is filled with waste OK NG Verify that the waste tubes are free of obstructions If the problem persists contact your local support provider or distributor 3 Check the availability of the reagents and wash solutions WARNINGS Read and follow the cautions on the box and label before handling any reagents Some method and system reagents are classified as hazardous material Avoid co...

Page 76: ...ts need replenishing 3 Replace any expired reagents IMPORTANT Do not move reagent containers on RTT1 or RTT2 after a barcode scan has been performed This can cause erroneous results If the operator accidentally switches barcoded reagents R1 reagent is loaded on RTT 2 and R2 reagent is loaded on RTT 1 and performs a reagent barcode scan and error message displays to alert the operator Replace barco...

Page 77: ... new lot numbers you must re calibrate the new set of reagents before you continue to run samples 1 At the Menu Panel select Reagent then select Reagent Inventory 2 Execute a Barcode Scan at the Reagent Inventory window 3 Evaluate calibration status 4 Perform a start up wash Set up of daily washes WASH 3 or Startup wash 26 minutes CTT position 51 DI water tube RTT1 position 56 DI water 70 mL conta...

Page 78: ...puter workorders 1 Create the workorders at your host computer Each patient sample must have a workorder that contains a sample number and at least one test request NOTE Stop here if you do not want to download workorders manually from the host computer before operation Instead use the Automatic item select feature in the Automatic transfer area on the Online Settings window 2 Download workorders ...

Page 79: ...e 7 Order tests by any of the following methods In the Test table select each test or ratio you want to run In the Test tbl no box enter the number of each test you want then press the period key In the Profiles area select each profile you want to run 8 To de select all tests select Delete Tests 9 To confirm select Yes 10 To erase all entries select Batch Func 11 To confirm select Yes 12 Select E...

Page 80: ...osi no and Samp no fields increment by the number of workorders requested from Batch Entry Deleting or changing test selectivity for multiple workorders 1 At the Menu Panel select Request then select Order Entry 2 Select Batch Func 3 Perform any of the following tasks at the window To erase workorders select Delete workorder To change the test selectivity select Test correct 4 In the Entry format ...

Page 81: ...load list contains only workorders that have position numbers To include workorders currently without position numbers use Creating List 1 At the Menu Panel select Request then select Order Entry 2 Select Create List 3 Select All or if you want to specify a range of position numbers select Posi no 4 If you selected Posi no define the tray and cup position a In the Last no entry format area select ...

Page 82: ...r remove the tray To remove the sample tray release the safety latches at position numbers 49 and 70 then grasp the sample tray by its handles and lift it out of the sampler well 4 Loading the samples a When using barcode labels Clean and properly position barcode labels on the sample tube Make labels face outward and visible through the slot in the sample tube holder Labels on tubes loaded in the...

Page 83: ... should be handled cautiously as a biohazardous material according to good laboratory practices The blood sample should be collected in a commercially available collection tube using routine venipuncture techniques A full discussion of sample collection and preparation is beyond the scope of this document however this subject is covered in detail in recent texts by Kaplan and Pesce and Tietz In ad...

Page 84: ...ick Do not allow the wooden stick to stand remain in the tube Perform this procedure carefully so the cells are not hemolyzed 3 If plasma is an acceptable sample type for the particular method draw the patient specimen into a tube containing acceptable anticoagulant lithium heparin or as indicated in the specific clinical method 4 Centrifuge the collection tube according to the tube manufacturer s...

Page 85: ... at different heights each container type must be defined separately in each sampling mode LAS or STT That is if the same container is to be used on the rack handler and the sample tray it has to be defined as two different container types one for LAS and one for STT The system defaults to container set 1 when a container is not specified with the host workorder NOTE If you are running patient sam...

Page 86: ... the Start Pause switch to start the rack handler CAUTION Do not push the carriers back into the outfeed buffer if for any reason you must remove the carriers manually from the system When the top cover is raised and the infeed pusher arm is in the up position avoid injury by bending over and coming into contact with the pusher arm 7 For continuous loading of new rack carriers push the Start Pause...

Page 87: ...ing the run WARNING If the system was stopped using the Emergency Stop button you must perform a Weekly wash WASH2 prior to processing samples 1 In the Operation Panel select Start The Start Conditions window displays 2 Perform any of the following tasks on this window run calibrators and reagent baselines RBL run control samples You cannot run multipoint calibrations while you are running patient...

Page 88: ... or for a range of positions as follows a In the boxes to the right of Analyze enter the range of positions you want to scan For example If you enter 50 and 60 The system scans for barcodes within this range and will aspirate only from positions at which it found barcodes b If you want the system to aspirate sample from a specific position or specific range of positions select Cup posi c Enter the...

Page 89: ...he rack handler on a day by day basis at the Review Data window 2 Use the Review Edit window on the ADVIA software to determine when results are available Running an interrupt STAT sample Running an interrupt sample when sampling is in progress START SMP LOAD NG 1 Download or create the sample workorder and select Interr interrupt option on the workorder NOTE You can also select the priority using...

Page 90: ...umber and sample position or by rack LAS position rack number and sample position The search returns a Sample Information window showing the sample number position number sample status and the time remaining to complete the analysis of the sample If a rack handler or laboratory automation system LAS is in use select the Rack or LAS Sample Info button to display the following sample information in ...

Page 91: ...found For example if sufficient sample was not available the s flag displays in the results Using the Sample Log 1 At the Menu Panel select Request then select Sample Log 2 Perform any of the following tasks at this window view the sample log entries search the sample log delete a specific sample log entry delete all sample log entries print a list of the sample log entries export the sample log e...

Page 92: ...r 3 To confirm select Yes Deleting all sample log entries 1 Select All Clear 2 When the All Clear dialog box opens do one of the following If you want to delete all entries for a specific day select Day In the list box select the file containing the sample log entries you want to delete The file for the current day is selected automatically If you want to delete the entire sample log select All 3 ...

Page 93: ...sed to accept or reject the ISE calibration Reviewing the sample results Sample results can be reviewed on and report from the RealTime Monitor and Review Edit windows Reporting results The system prints calibration control and patient sample results Only patient and control sample results are transmitted to a host computer Results are reported automatically as the sample analysis is complete and ...

Page 94: ... select the Print Report button 3 At the Print Report window select a Sample Type T and File Data F a If you select Archive in the File Data F field the Filing File Name I field is activated b Select the Open button c Select a file name at the Open window 4 In the Specification range R field select the arrow in the field and select Input Range or All from the list 5 In the Number entry format N fi...

Page 95: ... Maintenance Backing Up System Files NOTE When an automatic shutdown is performed a 1903 system error Shut down the system and reboot it message is generated to the system log Ignore this message 1 At the System S drop down list of the Menu Panel select Exit 2 When the confirmation message box displays select Yes 3 When the second confirmation message box displays select Yes After a brief delay th...

Page 96: ...cator 2 is off To place system in the SLEEP state use the following System p s Power OFF check box is selected check mark present System Select System end PRIME Select None WASH1 Do check box is cleared no check mark WASH2 Do check box is selected check mark present WASH3 Do check box is cleared no check mark Automatic startup with analyzer power kept ON To keep analyzer power on until the automat...

Page 97: ... prime you want to run or select NONE A Prime is required only if a system reagent is replenished or a related component is replaced 4 Select the check box next to each wash you want to perform Select WASH2 for the shutdown wash b Select Save c To confirm select Yes 5 In the Select wash routine area select Shutdown 6 In the Proc set list select the shutdown setting Set1 Set2 or Set3 you want to ru...

Page 98: ...When the power returns perform the normal startup operation Responding during a power failure while electric power is still off While the electrical power is still off do the following 1 Turn OFF the workstation power switch 2 At the power panel set the analyzer Operate Standby switch to Standby When the electrical power returns do the following 1 Turn ON the workstation power switch 2 When the St...

Page 99: ...f the test items at the System Test List window after initial setup If you reposition any test items at the System Test List window after initial setup results for samples already run could be associated with the wrong test name Loading the reagent trays CAUTION Load each reagent container wedge on the correct reagent tray to avoid erroneous results when using reagent containers without a barcode ...

Page 100: ...rval expires while the system is not running samples the automatic calibration is performed at the beginning of the next run However if the calibration interval has expired and controls are requested at the Start Conditions window the controls are run before the automatic calibration At the start of a run calibration and control samples are run using the following priority order 1 Manual calibrati...

Page 101: ...D value from the old lot to calculate the calibration curve If Auto Calibration with QC is enabled when placing a new lot of reagent on the system while the current lot is still in use monitor the Reagent Inventory window and ensure that a new calibration and QC run is performed on the new lot as soon as it becomes the Primary pack Alternatively pre calibration of a new lot can be performed prior ...

Page 102: ...102 ADVIA 1800 Operator s Guide ...

Page 103: ... determine standard values Refer to the IgA IgG and IgM method sheets for instructions about setting standard values and calibrator handling and preparation NOTE If you are running IgA_2 IgG_2 or IgM_2 this does not apply For multi point calibration methods simplified calibration is available after a valid multi point calibration is performed Use the ISE Parameter Settings window to set up calibra...

Page 104: ...Setting button in the MSTD column of the Procec test no list 2 To view the Multi Standard Setup window select Setting 3 In the TT no area select 98 or 99 4 In the Posi Box of the Blank row enter the cup position for the blank solution 5 For each standard do the following a Using the information in the calibrator package insert enter the Lot No Lot Name and Exp Date b In the Posi box enter the cup ...

Page 105: ...d define Meas time and Container Type 10 Select Save 11 At the Test Select window select the test 12 At the Sample Select window select the calibrators Running calibration Use the Start Conditions window to request a calibration run If needed you can run the calibration samples followed by controls and patient samples as appropriate You can limit calibration to selected calibration samples or to s...

Page 106: ...If the Select option is chosen then select one of the 3 Test Name options Photometric Displays all calibration history data for all photometric methods ISE Tests Displays all calibration history data for all ISE methods Other Activates the test list box to allow specific test selection highlight each test to display 4 Specify a date range to display data for calibrations performed on specific days...

Page 107: ...changes are retained when you exit out and back into the window 8 Select Print to print the data displayed 9 To create a CSV file of the displayed data for archiving or for exporting the data to another application do the following a First select the data you want to save b Select Create CSV c Browse and select a folder in which to save the CSV file d Select Save e Close the window ...

Page 108: ...108 ADVIA 1800 Operator s Guide ...

Page 109: ...ontrol samples Use the Start Conditions window to request control samples You can run control samples alone after calibration or before patient samples You can request to run only specific control samples or selected methods The Ordinary control samp meas list on the Test Select window determines which tests are available to run The Sample Select window determines which controls are available Use ...

Page 110: ...ollowing windows for reviewing QC Use the Real Time QC window to review control performance during the day Use the Daily Precision Control window to review the control results at the end of the day and then to update the cumulative statistics Use the QC Cumulative window to evaluate long term trends in control performance If control results fail to meet the laboratory s established criteria for ac...

Page 111: ...lash shields removed exposing the user to biohazard materials and moving parts Follow your laboratory standards and local environmental rules and regulations to avoid risk of infections when disposing biohazardous materials that come in contact with medical waste such as samples or analyzer parts CAUTIONS Use only the cleaning agents named in the cleaning procedures Using any other materials can c...

Page 112: ... than 100 dialysis samples a month or 330 routine samples a day wash electrode lines once a month Many maintenance procedures require that you set the analyzer to Standby before proceeding and after the procedure is complete return the analyzer to the READY mode To set the analyzer to Standby do the following 1 Save all data and close all open windows on the workstation 2 At the Menu Panel select ...

Page 113: ...rntable interiors Clean or replace reagent containers Clean the dilution bottle Clean the cuvette wash bottle Clean the chiller filter Clean the large water pump LWP filter Every 2 Months Clean the dilution tray cuvettes Clean and replenish the cuvette conditioner bottle Every 3 Months Replace the lamp Wash the ISE electrode lines Every 4 Months Clean the ancillary reagent bottle filters Clean the...

Page 114: ...o file the Audit Trail 1 From the menu panel select Maintenance 2 From the menu select Analytical Parameter Audit Trail In tabular form the Audit Trail provides the name of the screen where the change was initiated the date and time of the change the User Code the test name Version of the Chemistry Method before the change Version of the Chemistry Method after the change Analy Cond No Sub Param th...

Page 115: ...ve equipment Use universal precautions 1 Visually inspect each probe daily 1 Dilution Probe DPP 2 Sample Probe SPP 3 Reagent Probe 1 RPP1 4 Reagent Probe 2 RPP2 Figure 5 1 Location of probes Replace any clogged probes See Replacing the Probes in the online Operator s Guide Clean all probes daily proceed to step 3 TIP Perform the Shutdown Wash and Weekly Wash as scheduled to prevent the probes from...

Page 116: ... shield and remove 5 Unscrew all thumb screws then remove the splash guard protective covers from the wash cups NOTE If the system includes an anti rotation bracket avoid hitting it while removing the splash guard protective cover CAUTION Manually support lift the probe to avoid damaging the probe tip Be careful not to strike the probe against other components on the analyzer 6 Lift and manually r...

Page 117: ... is stable for one week when stored at room temperature CAUTION Do not use excessive force while cleaning to avoid bending the probes 8 Wipe the probe with alcohol prep pads or lint free towels and 5 bleach solution 9 Wipe the probe with lint free towels and deionized water 10 After cleaning ensure that no threads or fibers are left on the probes 11 Replace the splash guards and secure them back i...

Page 118: ...ip in a beaker of DI water and move the syringe plunger back and forth to dislodge the obstruction 9 After unblocking the probe optionally clean the probe with a 10 solution of bleach and perform step 10 Otherwise proceed to step 11 10 If bleach solution was used to clean the probe step 9 then rinse the probe with a syringe filled with DI water to remove any traces of bleach 1 Push In Fitting 2 Tu...

Page 119: ...pull the tubing out No tools are required To install the tubing simply push the tubing in Inspecting and cleaning the mixing rods and mixer wash cups Materials required Lint free towel Deionized water Cotton tipped applicators Time 5 minutes Analyzer mode STANDBY BIOHAZARD Wear personal protective equipment Use universal precautions Figure 5 4 Mixing rods 1 Dilution Mixer 2 Reagent Mixer1 3 Reagen...

Page 120: ...robably on the sensor Dry the sensor To clear the alarm message on the Operation Panel select the alarm icon Checking reagents and system solutions Refer to page 75 Checking the availability of the reagents and wash solutions in the Operating the System section in this manual or for more detail refer to the online Operator s Guide Monitoring Reagent Tray Temperature NOTE This procedure adds a mand...

Page 121: ...otective equipment Use universal precautions 1 Set the analyzer to Standby 2 Inspect the exterior of the reaction cuvette washer WUD and dilution cuvette washer DWUD tubing for cleanliness 3 Check the WUD and DWUD for leaks TIP Perform this inspection in addition to the startup shutdown and weekly washes to keep the WUD and DWUD from clogging In the event of a clog call your local technical suppor...

Page 122: ...al agent To prepare a 5 solution of household bleach dilute one part of bleach with nineteen parts of clean distilled water or clean deionized water The prepared solution is stable for one week when stored at room temperature 6 With alcohol prep pads or lint free paper towel moistened in 5 bleach solution wipe each wash head nozzle 7 Wipe each wash head nozzle with lint free towels moistened with ...

Page 123: ...rify the nozzles are correctly centered e At the DWUD or WUD window select Init then select Exit to raise the washer nozzles 12 At the Operation Panel select Initialize then verify the DWUD and the WUD are in the up position and the instrument is in the READY state Inspecting and cleaning the cuvette splash covers Materials required Lint free towel Deionized water Time 5 minutes Analyzer mode STAN...

Page 124: ... of the probe 1 Dilution Probe Wash Port 2 Sample Probe Wash Port 3 Reagent Probe 1 Wash Port 4 Reagent Probe 2 Wash Port Figure 5 8 Wash ports 1 Visually inspect each probe wash cup for cleanliness If any of the probe wash cups appear dirty clean them as described in the following steps 2 Set the analyzer to Standby 3 Using a Phillips screwdriver remove the screws securing the DPP shield to the a...

Page 125: ... sensor To clear the alarm message on the Operation Panel select the alarm icon 8 Replace the splash guards and secure them in place with the thumb screws 9 Replace the DPP shield and secure it in place 10 Return the analyzer to the READY mode Inspecting the pumps A decrease in liquid flow or the presence of air bubbles in the lines may be due to a leaking pump Inspect the pumps for leaks daily to...

Page 126: ...ted ensure each tubing connection is snug hand tightened c If leaks persist call your local technical support provider or distributor Figure 5 10 Pump plastic cylinder 3 Inspect the other pumps not SP and DIP for leaks The other pumps not SP or DIP are Dilution pump DCP Dilution discharge pump DOP Sample and reagent wash pump SRWP Reagent dispensing pumps RP1 and RP2 a Closely inspect the followin...

Page 127: ...Solution 1 CTT 16 Deionized water 1 CTT 49 10 Cuvette Wash Solution Daily 5 Reagent Probe Wash 3 Weekly 1 CTT 50 Deionized water 1 CTT 51 Deionized water 2 RTT1 53 Reagent Probe Wash 1 2 RTT1 54 Reagent Probe Wash 2 2 RTT1 55 10 Cuvette Wash Solution Daily 5 Reagent Probe Wash 3 Weekly 2 RTT1 56 Deionized water 3 RTT2 53 Reagent Probe Wash 1 3 RTT2 54 Reagent Probe Wash 2 3 RTT2 55 10 Cuvette Wash...

Page 128: ...Select WASH3 b Select 1 for Cycles c Type 51 in the CTT cup position 1st time field d Type 56 in the RTT1 and RTT2 bottle position 1st time field 5 Select Execute Performing the shutdown wash Materials required 10 solution of Cuvette Wash Solution REF 00195330 PN B01 4178 01 Deionized water ISE Detergent REF 01307361 PN B01 4174 01 Time 38 minutes Analyzer mode READY BIOHAZARD Wear personal protec...

Page 129: ...up positions 2nd time fields e Select Execute Performing additional ISE electrode washes Materials required ISE Detergent Solution REF 01307361 PN B01 4174 01 Time 5 minutes Analyzer mode Manual operation BIOHAZARD Wear personal protective equipment Use universal precautions WARNING Read and follow the cautions on the box and label before handling any reagents Some method and system reagents are c...

Page 130: ...e a cup of the ISE Detergent in the identified position on the screen b In the Container field select the type of container for the wash solution The recommended type of container is 6 2mlCUP Adp 4 In the Wash Electrode area select Execute then select Yes when prompted 5 At the ISE Operation window in the Period wash area select ON then select Set 6 Close the window then select Yes when prompted R...

Page 131: ... 1 Weekly wash this procedure 2 Lamp energy check 3 Cuvette blank measurement For location of washes on the CTT and RTT trays refer to Figure 5 12 WARNING Before handling any reagents read the warnings on page 196 1 At the Operation Panel select Wash 2 Ensure the 10 mL tube at CTT position 49 contains a 5 solution of Reagent Probe Wash 3 and that the cup at CTT position 15 contains ISE Detergent 3...

Page 132: ...a week even if the weekly wash is run daily Checking and replenishing the lamp coolant Materials required Lamp coolant additive REF 04533710 PN B01 4496 51 Deionized water Time 5 minutes Analyzer mode READY BIOHAZARD Wear personal protective equipment Use universal precautions The lamp is cooled by circulating liquid coolant As the volume of coolant decreases the heat of the lamp increases NOTE Ch...

Page 133: ...ing call your local technical support provider or distributor Checking lamp energy NOTES Check the lamp energy after cleaning or replacing cuvettes and after replacing the lamp When completing weekly maintenance be sure to perform the procedures in the following sequence 1 Weekly wash 2 Lamp energy check this procedure 3 Cuvette blank measurement Materials required No materials required Time 15 mi...

Page 134: ...e number of times to measure the lamp energy normal setting 1000 b Type 25 in the Meas cycle field Enter the time in µs to elapse after each lamp energy measurement normal setting 25 c Select AD d Select Auto 7 Select Meas Energy The message Execute the lamp energy check displays 8 Select OK 9 On the Lamp Energy Monitor window select Collect Data 10 Calculate the scatter plot a Note the value of t...

Page 135: ...the left of the graph 2 Select a wavelength for which to display data 3 Display the voltage or the AD value 4 Optional Change the vertical scale of the graph Measuring cuvette blanks NOTE When performing weekly maintenance be sure to perform the procedures in the following sequence 1 Weekly wash 2 Lamp energy check 3 Cuvette blank measurement this procedure Materials required No materials required...

Page 136: ...ean value Abnormal cuvettes A list containing abnormal cuvettes is printed as part of the cell blank The list contains marks indicating abnormality Cuvettes on the list are not used for analysis Abnormal cuvettes have the following characteristics Cuvettes exceeding the cell standard value set in the System Parameters System window are marked H or L Cuvettes exceeding the cell breakup limit value ...

Page 137: ...wer switch at the back of the analyzer to avoid catching the toweling in the cooling fans 2 Turn off the 15 A power switch at the back of the system 3 Close the analyzer cover 4 Prepare a 10 solution of bleach and DI water 5 Dampen lint free towels with the solution and wipe the following exterior surfaces top cover side panels front panel bear panel 6 Using deionized water wipe the exteriors agai...

Page 138: ... 5 2 a Using a Phillips screwdriver loosen the screws 1 that secure the DPP shield to the analyzer panel b Push the DPP shield to the right and slowly lift it to approximately a 90 angle c Gently lift the tab of the DPP shield and remove it 3 Remove all the CTT and STT covers a Remove the DPP splash cover secured in place with 3 Phillips screws b Remove CTT cover c Remove the STT evaporation cover...

Page 139: ...ble protective clothing gloves and eye face protection In case of contact with eyes rinse immediately with plenty of water and seek medical advice In case of contact with skin immediately wash with soap and water Avoid inhaling chemical vapors If you inhale chemical vapors promptly leave the area and seek fresh air 1 Remove Reagent tray loader 1 RTT1 a Lift and remove the cover from the reagent tr...

Page 140: ...resh solutions as specified in the table below RTT1 2 Position Wash Solution 53 Probe Wash 1 54 Probe Wash 2 55 10 Cuvette Wash 56 DI Water Cuvette wash and cuvette conditioner usage Cuvette Wash Solution Approximate Volume Used During Wash 2 Number of Aspirations Volume of Undiluted Cuvette Wash Used 10 Cuvette Wash DPP 7 2 mL RPP1 23 mL RPP2 23 mL 240 aspirations from RTT1 and RTT2 pos 55 5 5 mL...

Page 141: ...1 Set the analyzer to Standby CAUTION Note the bottle position on the shelf to avoid mixing up the fluid bottles 2 Lift the cover from the saline diluent bottle 1 and remove the bottle 3 Empty the remaining contents of the bottle 4 Rinse the bottle with deionized water and drain well 5 Refill the bottle with 0 9 saline diluent 6 Replace the bottle in the same position on the shelf in the cabinet 7...

Page 142: ...e universal precautions NOTE The cuvette wash bottle may be cleaned when it is refilled but must be cleaned at least once a month 1 Cuvette Wash Detergent Bottle 2 Level Sensor Connector 3 Filter Cap Figure 5 17 Cuvette wash bottle 1 Set the analyzer to Standby 2 Unscrew the filter cap 3 at the front top of the cuvette wash bottle then pull up the tube with the filter 3 Disconnect the cuvette wash...

Page 143: ... button c At the PRIME Settings dialog box select Prime 2 and then type 10 or more for the number of times in all fields d Select Execute Cleaning the chiller filter Materials required Vacuum cleaner Time 10 minutes Analyzer mode STANDBY BIOHAZARD Wear personal protective equipment Use universal precautions NOTE The chiller filter is located on the right inside bottom shelf of the analyzer cabinet...

Page 144: ...d cuvettes CAUTION Turn the analyzer OFF while cleaning the LWP filter 1 At the Operation Panel select System s then select Exit 2 When the Startup window opens switch the analyzer to OFF 3 Using a Phillips screwdriver remove the 2 screws 2 from metal bracket securing the water filter 1 Metal Filter Bracket 2 Phillips Screw 3 LWP Filter Figure 5 18 Location of LWP filter IMPORTANT Be sure to label...

Page 145: ...f the filter making sure the black o ring is in place 9 Reinstall the filter in the system a Maintaining proper tube to filter orientation push one of the tubes into the elbow as far as it will go b Repeat for the other tube c Do not replace the metal bracket at this time 10 At the StartUp window select New Start or Restart 11 Return the analyzer to the WAIT mode 12 Check the system for leaks a At...

Page 146: ...es Probe Wash 3 is a corrosive material that can cause burns Wear suitable protective clothing gloves and eye face protection In case of contact with eyes rinse immediately with plenty of water and seek medical advice 1 Prepare 1 5 liters of 5 Probe Wash 3 solution diluted with deionized water 2 Set the analyzer to Standby 3 Remove the 6 cuvette segments on the dilution tray DTT a Unfasten the 2 t...

Page 147: ... mode field displays READY before performing any further actions 10 At the Operation Panel select WASH 11 Perform the daily shutdown wash routine then verify the operation Cleaning and replenishing the cuvette conditioner bottle Materials required Deionized water Cuvette conditioner Time 10 minutes Analyzer mode STANDBY BIOHAZARD Wear personal protective equipment Use universal precautions NOTE Th...

Page 148: ...at the level sensor connector 2 does not get wet to avoid damaging it 8 Refill the bottle with cuvette conditioner 9 Return the bottle to the same position on the shelf in the cabinet 10 Connect the cuvette conditioner bottle level sensor connector then push the connector in and turn clockwise 11 Insert the filter and hose then fasten the cap NOTE Make sure that the filter holder is located at the...

Page 149: ... points are outside the 40 range of the scatter plot center line or the volts for any of the wavelengths are outside the range of 5 0 to 9 0 volts If the ATTENU for any of the 14 wavelengths on the Lamp Check Energy window falls below 80 1 Lead Wire Connector 2 Lead Wire Connector 3 Lamp Screws 4 Lamp Plate 5 Alignment Hole and Pin Figure 5 22 Components of the lamp 1 Set the analyzer to Standby 2...

Page 150: ...nol 6 Install the lamp screws 7 Install the lead wires and fasten the knobs 8 Replace the access panel 9 Return the analyzer to the READY mode if necessary 10 Wait 40 minutes for the lamp to stabilize NOTE You can perform the daily shutdown 2 while you are waiting 11 Check the lamp energy see the Weekly Maintenance section 12 Register the data and verify that attenuations register at 100 voltages ...

Page 151: ... the Menu Panel select Maint then select ISE Operation 2 Remove the Na K Cl and Reference electrodes and place in ISE buffer solution 3 Install the dummy electrode 2 in place of the 4 electrodes removed in step 2 4 Secure the dummy electrode in place by positioning the retaining bracket 3 over the electrode then tightening the thumbscrew 4 Figure 5 24 Replacing the electrodes with a dummy electrod...

Page 152: ...M STOP button on the analyzer display panel This step takes approximately 17 minutes to complete This step takes about 17 minutes 8 When step 1 of the wash completes replace the dummy electrode with the original Na K Cl and Ref electrodes 9 At the ISE Operation window in the ISE line wash area select Execute STEP 2 The wash starts and buffer prime is performed 10 times The message Line Wash 2 Runn...

Page 153: ...ticles or dirt 5 If dirty clean the filters as follows NOTE An additional set of filters is included with the analyzer Locate the spare filters and place them on the system to avoid downtime while the dirty filters are cleaned a Place the filters in a beaker filled with a freshly made 10 solution of household bleach and water b After 30 minutes remove the filters c Rinse them in deionized water d ...

Page 154: ...ew one resume operation and then clean and store the removed filter for the next scheduled maintenance 1 Silicon Return Hose 2 Pure water bottle Figure 5 25 Pure water bottle 1 Set the analyzer to Standby 2 Remove the silicon return hose 1 from the top front of the pure water bottle 2 The filter is contained in a metal filter holder attached to the end of the return hose 1 Metal Filter Holder 2 Si...

Page 155: ... soaked in alcohol clean the outside surfaces of the filter holder and hose 9 Insert the silicon filter hose into the water bottle 10 Prime the lines a Return the analyzer to the READY mode b At the Operation Panel select the PRIME button c In the PRIME Set dialog box select PRIME 2 and type 10 or more for the number of times in all fields d Select Execute Replacing the reaction and dilution cuvet...

Page 156: ...instrument Do not remove the cuvette if it is in front of the detector 3 b Hold the cuvette set by the tab 2 and lift it from the tray c To remove the cuvette sets located by the detector unit or under the cuvette wash station WUD rotate the reaction tray by hand until the cuvettes are in an accessible location 3 Inspect the reaction bath oil around the bath ring removing any particulate matter wi...

Page 157: ... are clear 6 Install the new cuvette sets on the DTT and fasten the set screws by hand 7 Return the analyzer to the READY mode 8 Perform the daily Shutdown wash WASH2 routine and verify the operation 9 Perform the lamp energy check procedure 10 Perform the cell blank measurement and if the cell blank run was completed successfully save the results ...

Page 158: ...ted format the disk as follows a Close the ADVIA software then at the main Startup window select Cancel b Insert the labeled disk into the CD DVD drive c At the Windows taskbar right select Start then select Explore d In the left pane of the Explorer window locate and right select the CD DVD drive E or X e Select Format f On the Drag to Disc Format Options window select Full Format g Select OK h O...

Page 159: ...e Data Files checkbox at the ADVIA Backup window This deletes any current data files on the PC hard drive before the backed up system and data files are restored If the current data files are needed perform a backup before restoring previous files The restore feature restores all files system and or data files that were previously backed up If this is the case close the ADVIA Backup window and per...

Page 160: ...PP probes with crash detection 1 Dilution Probe DPP 2 Sample Probe SPP 3 Reagent Probe 1 RPP1 4 Reagent Probe 2 RPP2 Figure 5 28 Probes Removing a probe 1 Set the analyzer to Standby CAUTION Manually support the probe and be careful not to strike it against anything on the analyzer to avoid damaging the probe tip when the power is off 2 Cover the cuvettes wash cups and other analyzer surfaces with...

Page 161: ...ts 5 Cover the 12 volt LLS amplifier and wires with a lint free paper towel 6 Using the pliers loosen the joint connector 2 turning counterclockwise then unfasten and remove it by hand 7 Loosen but do not remove the 4 Phillips screws 4 NOTE Be careful not to drip any fluid from the probe onto the amplifier If needed drain fluid into a container ...

Page 162: ... the joint holder CAUTION Do not cross thread or force the joint connector in too far to avoid damaging the threads or introducing leaks or air bubbles 4 Finger tighten the joint connector 2 5 Check that water is not leaking from the Joint Connector 6 Remove the lint free paper towel 7 Replace the probe arm cover and tighten the two probe cover screws 8 Lift up the probe arm to the end of its trav...

Page 163: ...els Time 10 minutes Analyzer mode STANDBY BIOHAZARD Wear personal protective equipment Use universal precautions 1 Dilution Probe DPP Figure 5 31 Dilution probe Removing the DPP probe cover 1 Set the analyzer to Standby 2 Using a Phillips screwdriver remove the screws 1 that secure the DPP shield to the analyzer panel 3 Push the DPP shield to the right and slowly lift it until it reaches approxima...

Page 164: ...ut do not remove the screws on each side of the probe cover 1 9 Lift the cover from the probe arm and set it aside Removing the probe from the probe arm 1 Probe Tubing 2 Joint Connector 3 Joint Holder 4 Probe Wire Screw 5 Black Wire 6 Spring Clips 7 Probe Guide 8 Probe 9 Wire Lock Screw Figure 5 32 DPP probe without cover 1 Gently loosen the probe joint connector 2 use pliers if necessary then sli...

Page 165: ...int connector 2 into the back end of the probe and carefully tighten until snug 2 Press the joint end of the probe into the joint holder 3 CAUTION Do not cross thread or force the joint connector in too far to avoid damaging the threads or introducing leaks or air bubbles 3 Carefully close each spring clip 6 over the probe CAUTION Do not allow the clips to snap on the probe shaft This may cause da...

Page 166: ... SPP RPP1 and RPP2 over cuvettes DPP should be over cuvette 1 on the DTT 4 Ensure that the probe is perpendicular to the arm and centered over the cuvette If it is not call your local technical support provider or distributor 5 At the Operation Panel select Prime then PRIME 2 then Execute to ensure proper water flow through the probe 6 Verify that water is not leaking from the joint connector 2 Re...

Page 167: ...TION Make a note of the bottle position on the shelf to avoid mixing up the fluid bottles 4 Remove the RRV bath oil bottle 1 CAUTION Ensure that level sensor connector 2 does not get wet to avoid damaging it 5 Refill the bottle with RRV reaction bath oil 6 Replace the bottle on the shelf in the cabinet 7 Connect the RRV bath oil bottle level sensor connector 2 by pushing the connector in and turni...

Page 168: ...and eyes Probe Wash 3 is a corrosive material that can cause burns In case of contact with eyes rinse immediately with plenty of water and seek medical advice Wear protective clothing gloves and safety glasses when handling bleach It is harmful if swallowed and may cause eye or skin irritation Household bleach is 5 or 6 sodium hypochlorite In case of contact with eyes rinse immediately with plenty...

Page 169: ...e movements can cause injury or damage to the nozzles 2 Prepare the WUD DWUD for cleaning a With the system in READY mode log on as supervisor b Place paper towels on top of the RRV and DTT cuvettes directly under the WUD DWUD nozzles as a precaution c Using a 4 mm hex wrench loosen the captive screw 1 that secures the WUD DWUD wash head to the WUD DWUD mechanism Figure 5 34 WUD and DWUD captive s...

Page 170: ...kes about 65 70 seconds This sequence activates the appropriate devices so all the WUD DWUD aspiration nozzles and overflow nozzles are pulling vacuum The overflow lines short nozzles aspirate air after a short while as the liquid in the container lowers This is normal behavior 6 When the operation mode returns to READY lift the WUD DWUD wash head out of the tray and temporarily place it on top of...

Page 171: ...tion then place it on paper towels under the WUD DWUD nozzles 14 Place the WUD DWUD wash head into the tray then fill the tray with 150 mL of deionized water 15 Repeat step 5 twice to flush out the cleaning solution with deionized water 16 When the operation mode returns to READY move the WUD DWUD wash head on top of the WUD DWUD assembly and secure it by tightening the 4 mm captive hex screw 17 R...

Page 172: ...utions 1 At the Menu Panel select Maint then select ISE Operation 2 In the Period wash area select OFF then select Set 3 Open the front doors and replace the buffer solution 1 with another buffer bottle containing 500 mL of deionized water Figurer 5 36 Location of ISE Buffer bottle 4 Loosen the thumb screw and lift the ISE cover 5 Disconnect the electrode connectors 6 Remove the thumbscrew 1 to re...

Page 173: ...olution 2 At the ISE Operation window in the Bufferprime area enter 50 in the Times field 3 Select Execute 4 When prompted select Yes to execute the buffer prime Rinsing the lines 1 Replace the probe wash 3 solution bottle with a bottle of deionized water 2 In the Bufferprime area enter 50 in the Times field then select Execute 3 Remove the dummy electrode 4 Reinstall the Na K and Cl electrodes 5 ...

Page 174: ...ions Replace the Na K and the Cl electrodes if the slope is incorrect or calibration continuously fails The acceptable ISE slope is between 45 0 and 63 0 Slopes outside of this range are flagged as shown in the table A flagged slope fails the calibration The slope limits are defined at the ISE Parameter Settings window Mark ISE Slope Range H 65 0 h 63 1 to 65 0 l 38 0 44 9 L 38 0 Replace the refer...

Page 175: ...ctrode and that the ridges on the side of each electrode fits into the depressions on the side of the electrode next to it CAUTION Do not force the electrode If a space exists between the electrode connections the plate retaining the electrodes cannot close If you cannot close it move each electrode left and right little by little Fasten the thumbscrew tightly If the retaining plate loosens during...

Page 176: ... is automatically turned on 11 After initialization is complete select Exit then select Yes Calibrating the ISEs 1 At the Operation Panel select Initialize 2 At the Menu Panel select Maint then select ISE Operation 3 At the ISE Operation window in the Calibration area select Execute 4 When prompted select Yes to execute calibration 5 If the calibration fails repeat calibration again and if data co...

Page 177: ... Prepare a 1 4 dilution of pool serum using ISE buffer solution 2 Remove the new electrode from its case NOTE The ion electrode contains an inner solution which can be confirmed by shaking the electrode This solution decreases little by little with time If you do not feel any response in your shaking measure its weight If the electrode weighs less than 9 g do not use it 3 Remove the sponge from th...

Page 178: ...l protective equipment Use universal precautions Cleaning the dilution bowl 1 At the Menu Panel select Maint then select ISE Operation 2 At the ISE Operation window in the Period wash area select OFF then select Set 3 Using a Phillips screwdriver remove the screws 1 see Figure 5 2 that secure the DPP shield to the analyzer panel 4 Push the DPP shield to the right and slowly lift the DPP shield unt...

Page 179: ...n a lint free gauze and wipe off any crystals remaining on the nozzle 16 Using deionized water moisten a lint free gauze and wipe up water and dirt particles remaining in the dilution bowl 17 Replace the nozzle with its guide and secure it with the thumb screw 18 At the ISE Operation window enter 5 in the Bufferprime Times box then select Execute 19 When prompted select Yes to execute a buffer pri...

Page 180: ...e ISE unit by sliding it into place then secure it with the retaining screw CAUTION When sliding the cover be careful not scratch the tubes and dilution bowl Also when fastening the screw verify that the cover is not caught in the groove and is not loose 2 Reinstall the ISE cover and tighten the screws 3 Reinstall the DPP probe shield 4 At the ISE Operation window in the Initialize area select Exe...

Page 181: ...ts listed below refer to the Troubleshooting section of the online Operator s Guide System error messages NOTE The error message log on the analyzer also has information to guide you through resolving error messages Sample dilution checking DPP waveform Reagents RPP reagent detection ...

Page 182: ...182 ADVIA 1800 Operator s Guide ...

Page 183: ...as follows a At the Windows taskbar select Start then select Settings b Select Printers and Faxes c At the Printers and Faxes window right select the printer marked with a checkmark default printer d Select Cancel All Documents e When prompted select Yes f Close the Printer and the Printer and Fax windows 9 Turn the printer on 10 Copy the file to a CD or a DVD as follows a Place a formatted CD or ...

Page 184: ... You can open the file using a spread sheet program such as Microsoft Excel You can save the file to a diskette CD or to the system PC hard drive Saving test data 1 Verify that the analyzer is in READY or WAIT mode 2 Insert a formatted CD or DVD into the CD DVD ROM drive 3 Select the Drag to Disc icon located to the left of the time display in the lower right corner of the window 4 Select Request ...

Page 185: ...me display in the lower right corner of the window 4 Select Request then Review Edit and make a note of the filing date of the samples you want to save Saving by order number works best but you can use sample Based on when you performed a New Start the system stores data for 7 filing dates After that the data with the oldest filing date is deleted 5 Select Request then Reaction Monitor 6 Select th...

Page 186: ... to save all 7 filing dates at one time weekly and create a system backup at the same time 1 Verify that the analyzer is in READY or WAIT mode 2 Place a formatted CD or DVD into the DVD CD RW drive on your PC 3 Select Request then select Review Edit and note the filing date of the samples to save 4 The system stores data for 7 filing dates based on when a New Start is performed After that the data...

Page 187: ...to the DVD CD RW drive on your PC 3 Select Request then select Review Edit 4 Select Archive from the filing option in the pull down menu The Filing button becomes active 5 Select the Filing button and select the CD DVD 6 Select on the file date of the data to view 7 Follow the same steps to view the reaction data at the Reaction Monitor window ...

Page 188: ...188 ADVIA 1800 Operator s Guide ...

Page 189: ...Order Entry window 4 Use the Item Setting dialog box at the Online Setting window to determine which test results to transmit and to assign host test numbers 5 Use the Data Clean Setting dialog box at the Online Settings window to have the system automatically validate the sample results before they are transmitted Use the Transfer Results List dialog box of the Review Edit to review the data clea...

Page 190: ...perational or cancelled Chemistry ISE Unused Labo Auto Sys Rack Handler Clot Detection settings 1 In the Clot detect area select Avail to use the clot detection feature or N A to disable it 2 In the Clot sensitivity area select Low Middle or High to select the sensitivity of the clot detection sensor Setting up the ISE This section describes the steps required if the present configuration for the ...

Page 191: ...rd deviation from the product package insert ISE calibration Verify that the CTT position setting at the ISE Parameter Settings window agrees with the actual positions where you place the ISE standard on the CTT Run the ISE calibration using one of the following modes Start button single point calibration ISE Operation window Use the ISE Monitor window to review the calibration Checking ISE calibr...

Page 192: ...le Buffer 388 5 ELASTDSL013 Na Sample Buffer 387 0 Difference 1 5 Exceeds clearance value of 1 0 another aspiration occurs 4 Steps 2 and 3 are repeated for the ISE low calibrator A maximum of 8 sample aspirations can occur 5 Twelve seconds after the last ISE low calibrator is aspirated the system takes one additional aspiration and uses it to determine the chloride bias 6 The third check is for th...

Page 193: ...on u or d that is defined in the Reanalysis conditions area Automatic use of an alternate diluent is also available Use Rerun Condition in the ISE Parameter Settings window to request a rerun if an ISE result is flagged Use the Rerun Condition feature in the Ratio Parameters window to request a rerun if a ratio is flagged Processing the rerun automatically Use Auto Retest on the System Specificati...

Page 194: ...194 ADVIA 1800 Operator s Guide ...

Page 195: ...tion 2005 CLSI Document M29 A3 This document contains complete information on user protection and it can be used as reference material for instructions on laboratory safety Electrical warning ELECTRICAL WARNING To avoid exposure to shock hazards and or damage to the instrument while performing this procedure power off the analyzer before proceeding Laser warning LASER WARNING To avoid damage to th...

Page 196: ... solution of household bleach dilute one part of bleach with three parts of clean distilled water or clean deionized water The prepared solution is stable for one week when stored at room temperature Ancillary and method reagents warnings WARNINGS Read and follow the cautions on the box and label before handling any reagents Some method and ancillary reagents are classified as hazardous material A...

Page 197: ...sified as a Class II laser device having a maximum power output of 1 2 mW at a wavelength of 670 nm a pulse duration of 127 ns and 4 78 mr units of beam divergence The analyzer reagent tray barcode readers RTT1 RTT2 are classified as Class I LED devices having a maximum power output of 25 5 mW at a wavelength of 655 nm and a pulse duration of 200 ns 1 Reagent Barcode Reader RTT2 2 Reagent Barcode ...

Page 198: ...198 ADVIA 1800 Operator s Guide ...

Page 199: ...resentative or authorized distributor will inform the customer of the type of service available for the customer s instrument and will instruct the customer as to how to obtain that service CAUTION Please observe the warning and hazard statements appearing throughout the online operator s guide If the ADVIA 1800 Chemistry system is used in a manner not specified by Siemens the protection provided ...

Page 200: ...rized distributor Service performed outside normal hours is subject to a surcharge unless the customer has in place a service product option that provides service at the time s requested Replacement of parts In performing service Siemens or its authorized distributors will provide appropriate parts to repair the instrument or will arrange for the exchange of the instrument or affected parts at no ...

Page 201: ... the system operator s manuals 12 Damage was caused by water from any source external to the instrument 13 The customer has purchased an alternative agreement whose terms of warranty or service supersede these provisions 14 Injury or infectious disease caused by transportation or disposal without supervision by a Siemens representative Siemens or its authorized distributors will invoice customers ...

Page 202: ...t the instrument s performance characteristics OSHA requirements When service is required at a customer location the customer must provide the Siemens representative with adequate facilities that comply with the regulations of the Secretary of Labor under the Occupational Safety and Health Act OSHA of 1970 as amended Software License No title or ownership of software is transferred to the customer...

Page 203: ...ated in the United States you can contact the Customer Service Department by calling toll free 1 877 229 3711 If you are located outside the United States please contact the Siemens office nearest you Siemens Offices Worldwide www siemens com diagnostics ...

Page 204: ...204 ADVIA 1800 Operator s Guide ...

Page 205: ...4 01 01448895 Pure water bottle Filter set LWP 094 0037 01 04872841 Guide sample cup STT CTT 073 0346 01 08056461 ISE cell base assembly 094 0024 01 07096842 ISE dummy electrode 073 0646 01 05938765 ISE ground assembly 094 B015 01 04412484 ISE screw probe guide 094 0089 01 06616737 ISE screw seal retainer 094 0090 01 01467717 ISE screw waste nozzle 094 0091 01 05094109 Lamp Halogen 12V 50W 073 009...

Page 206: ...3 01 00311764 Sample cup 1000 PKG 073 0157 02 01390706 Screw thumb cuvettes 4x6 073 0384 01 07199951 Screw thumb 3x6 073 0385 01 02291299 Shield DPP 073 0951 01 04457097 Splash cover RPP1 073 0859 01 02122926 Splash cover RPP2 073 0860 01 08425947 Splash cover SPP 073 0861 01 03102155 Splash cover CTT STT 073 0950 01 08176645 Waste bottle 073 0383 01 09457923 ...

Page 207: ...y Hitachi 2 mL sample cups and Ez Nest 2 mL sample cups in 7 mL 16 x 75 mm collection tubes URH or STT sample adapter dead volume for sample cups is 50 µL Trays STT Used for general samples and calibrators for multipoint calibration assays Two lines outer and inner of 42 samples each Total positions in STT tray 84 Sample barcode 13 digits Code 39 Codabar and Interleaved 2 of 5 Code 128 CTT URH Use...

Page 208: ...ion Reagents on each tray are cooled to between 6 C and 14 C Container capacity 20 40 or 70 mL Refrigerator All method reagents Reagent volume item 15 to 150 µL 0 1 µL increments Dilution reagent volume 15 to 150 µL 0 1 µL increments Reagent inventory Computed by the liquid level sensing Barcode Interleaved 2 of 5 Reaction Reaction tray RRV Turntable system Number of cuvettes 221 13 sets of 17 cuv...

Page 209: ...ding option Sample blank correction Reassay mechanism Automatic or manual selectable Automatic correction Blood serum blank cell blank measurement point change sample volume change in reassay ISE Method Na K Cl ion selective electrolyte assay Dilution measurement method Analysis item Simultaneous 3 item measurement of Na K and Cl Electrode Na Crown ether membrane K Crown ether membrane Cl Super la...

Page 210: ...ion with Class III grounding The following input voltages can be tapped 200 220 230 or 240 VAC at 50 60 Hz Main supply voltage fluctuations not to exceed 10 percent of the nominal voltage Maximum current draw at in rush is 15 amps at 200 VAC or 13 amps at 240 VAC For the optional universal rack handler the requirements are 110 Vac 50 60 Hz 0 6 A Facility Switch Box Should contain a circuit breaker...

Page 211: ...s to ensure proper operation as per the Site Survey for each ADVIA Chemistry system Resistivity 10 0 Megaohm cm 25 C Bacteria 10 cfu mL Silica 0 05 mg L Total Organic Carbon 200 µg L Total Dissolved Solids 1 0 mg L In addition the following specifications should be met to ensure proper operation Temperature of water entering the system is between 10 C and 30 C Dissolved Oxygen 7 0 mg L Direct plum...

Page 212: ...212 ADVIA 1800 Operator s Guide ...

Page 213: ...symbol indicates a moving component that can cause injury This symbol alerts you to a potential electrical hazard This symbol alerts you to the risk of exposure to lasers The onboard sampler is equipped with a laser barcode reader When covers are opened there is a risk of radiation exposure Do not stare into the beam This symbol alerts you to a potential biohazard Biohazard labels are also placed ...

Page 214: ...Standby symbol Some parts of the system are on Some parts of the system are off Alarm symbol Stop button Reset button Prime button Error log Indicates consult online instructions Operator s guide Wash button I indicates closed circuit or On O indicates open circuit or Off ...

Page 215: ...Revision letter of a part or product Serial number of part or product Number used for ordering a part or product An in vitro diagnostic device Product is a Class 1 laser product under the provisions of 21 CFR 1040 10 The WEEE symbol indicates that this equipment is classified as Waste Electrical and Electronic Equipment under the European WEEE Directive It must be recycled or disposed of in accord...

Page 216: ...zer Computer monitor Computer workstation Vacuum pump pressure gage Reagent tray 1 Reagent tray 2 Controls and calibrators tray Sample tray Use these arrow symbols to align the tray covers Ancillary reagent symbols Deionized water symbol on the reagent and sample trays 10 cuvette wash Probe wash 1 Probe wash 2 ISE De ISE detergent ...

Page 217: ... Isotonic saline diluent connector Incubation bath oil connector Cuvette wash connector Cuvette conditioner connector ISE buffer connector Strong concentrated drain bottle sensor connector Concentrated drain bottle sensor connector ...

Page 218: ...maximum storage temperature for the package The specified range may vary Contents of the package should be protected from heat and light Product or container should be oriented in the direction of the arrows Package is printed with soy ink Contents of the package must not be frozen Number of tests available from the contents of this package Packaging materials can be or are recovered and recycled ...

Page 219: ...r A clot is detected N N N b Pack switch A pack was switched during calibration N Y C Calibration error Photometric tests no or faulty calibration ISE tests ISE calibration range error Y cal error Y cal error N cal error d Photometric tests Abnormal reaction absorbance lower ISE tests dilution error refernce electrode value is less than 500 Y N Y Y N N D Absorbance limit lower Lamp energy low duri...

Page 220: ...eeded Y Y K Maximum absorbance limit exceeded The maximum absorbance limit is exceeded NOTE This flag is linked to the Max Limit field at the Analytical Parameters Chemistry window Y Y k Exceeded the calibration low range The calibration low range is exceeded Y Y M Mix error A mixer motion error is detected Y Y N n Abnormal number of effective points Insufficient valid data points Y Y N N Cell bla...

Page 221: ... system error Y Y N t Insufficient diluent Y Y N T Thermistor ISE Abnormal thermistor Y Y N r Photometric test insufficient reagent Y Y N R Rerun result Indicates that a test result is a rerun Y Y Y u Photometric tests abnormal reaction absorbance upper Y Y N U Absorbance upper Lamp energy high during cell blank measurement check Photometric tests abnormal reaction absorbance upper Y Y N ...

Page 222: ...6050 B JEOL Ltd 1 2 Musashino 3 Chome Akishima Tokyo 196 8558 Japan Tel 81 42 542 2303 Fax 81 42 542 3132 Manufacturer of ADVIA 1800 System Siemens Healthcare Diagnostics Inc 511 Benedict Avenue Tarrytown NY 10591 5097 USA Tel 914 524 3001 Fax 914 524 2088 ...

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