Roche CoaguChek XS Pro, Operator'S Manual

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Introduction •
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The meter guides you through the test, step by step,
using icons and instructions on the display. Each box of
test strips has its own code chip that you insert into the
meter. This code chip contains lot-specific information
about its test strips, such as the expiration date and cali-
bration data. Optional liquid controls for the system are
also available.
The CoaguChek XS Pro meter has the ability to connect
to a data management system (DMS) through the Hand-
held Base Unit from Roche (available separately). The
CoaguChek XS Pro meter supports data exchange via the
POCT1A standard. Data management systems may have
the ability to expand the security features of the meter,
such as enabling operator lockouts. Data management
systems may also enable data transfer to an LIS or HIS.
Refer to the manuals of the Handheld Base Unit and of
your DMS for technical details.
Test principle
The CoaguChek XS PT Test contains a lyophilized rea-
gent. The reactive components of this reagent consist of
thromboplastin and a peptide substrate. When a sample
is applied, thromboplastin activates coagulation, which
leads to the formation of thrombin. At the same time the
meter starts to measure the time. The enzyme thrombin
cleaves the peptide substrate, generating an electro-
chemical signal. Depending on the time elapsed when it
first appears, this signal is then converted by means of an
algorithm into customary coagulation units (INR, %Quick,
seconds) and the result is displayed.