MNL-1017 Rev A
9
Cleaning the Flow-Cell
A clean flow-cell is important for accurate measurements. Scale, debris, scratches, and other detritus can degrade the signal. If the
flow-cell is chipped, scratched, or the transparency is otherwise compromised it will need to be replaced. To prevent unnecessary
replacement, ensure your flow-cell is clean after use. After sampling, prior to filling with clean water, the flow-cell should be flushed
clean with a solution appropriate for the sample being measured. See below for recommended cleaning solutions.
Solvent
Material
Suggested Cleaning Methods
Aqueous
Protein, DNA, Biologics
Warm water with detergent, Dilute acid rinse, Copious water rinse
Aqueous
Salt solution Warm water Acid rinse, copious water rinse
Aqueous
Basic solutions
Warm water with detergent, Dilute acid rinse, Copious water rinse
Organic
Oil based
Rinse with solvent, Warm water with detergent, Dilute acid rinse, Copious water rinse
Organic
Alcohol solutions
Rinse with solvent, Copious water rinse
Organic
Acidic solutions
Rinse with solvent, Copious water rinse
Organic
Basic solutions
Rinse with solvent, Dilute acid rinse, Copious water rinse
The use of RO, or distilled water, is highly recommended to prevent scale. After cleaning, the flow-cell should not be allowed to dry out
and should be stored filled with RO or distilled water.
Summary of Contents for LTMS
Page 2: ......