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Description
This chapter provides background information on the system, including
descriptions of the principal components and overviews of how the
system functions. It is divided into the following sections:
•
•
How To Use This User Guide, see page 9
•
Safety Information, see page 9
•
•
System Components, see page 15
•
Overview of Operation, see page 32
•
Theory of Operation, see page 33
•
SoftMax Pro Software, see page 41
Introduction
The FlexStation® 3 Benchtop Multi-Mode Microplate Reader combines
the performance of the Molecular Devices SpectraMax® M5e Multi-
Mode Microplate Reader with an integrated 8-channel or 16-channel
pipettor into one compact benchtop reader. This integrated system
provides users with a multi-detection platform capable of increasing the
liquid handling throughput and flexibility for biochemical-based and cell-
based assays. Using an integrated 8-channel or 16-channel pipettor
increases assay flexibility by transferring reagents from 96 or 384 distinct
wells in a source plate to the read plate. This method enables users to
define individual reagents or compound concentrations to be delivered
to each well during the assay. The direct transfer from a source
microplate reduces consumption and allows more assay conditions to be
explored in a single microplate, making the system equally amenable to
agonist and antagonist assay formats. These additions can either occur
concurrently with kinetic analysis of reactions or before an assay to
automate reagent additions. Combined fluid transfer with multi-
detection optics provides a single reader capable of performing a broad
span of applications that pass through drug discovery and research
environments.
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