Millipore Sigma Pellicon 3 Cassettes Installation And User Manual Download Page 4

Pellicon

®

 3 Cassettes Installation and User Guide 

4

11.  Using the  torque wrench and 15/16 in. 

deep hex socket, turn each nut 1/8 turn 

in the sequence shown here. When the 

wrench clicks, this indicates that the set 

force has been reached.  DO NOT OVER 

TORQUE.  Evenness of torque is critical 

to system performance. 

NOTE 

Depending on the results of the 

Integrity Test, the torque may need 

to be increased at intervals of 50 

in-lb (5.6 Nm) up to a maximum of 

550 in-lb (62 Nm).

12.  Recheck the torque prior to use.

NOTE 

If the filter holder is tightened in a 

cold area and moved to a warmer 

area, loosen the nuts entirely, let 

the filter holder warm up, and then 

retighten to prevent warping of the 

end plates.

Pellicon

® 

 Holder Tightening Sequence

Exploded View of Stainless Steel Pellicon

® 

  

Cassette Filter Holder.

retentate

outlet port

permeate

outlet port

top

plate

manifold

threaded

tie rod

threaded

holes for

insertion

of tie rods

bottom

plate

manifold

1in. sanitary

Tri-Clover®

connection

feed inlet

port

3/4 in. sanitary

Tri-Clover

connection

Pellicon

Cassette

hex nut

washer

stainless steel

bushing

handle

PERMEA

TE

RE

TENT

ATE

FEED

Pellicon10_2_06_2.eps 

Gasket Plate

manifold adapter 

plate

®

®

nut

PER

MEA

TE

RETENT

ATE

FEE

D

MILLIPORE

washer

stainless steel

bushing

top

pressure plate

tie rod

permeate

manifolds

(four holes)

pressure

gauge

bottom

pressure plate

bottom

manifold plate

Pellicon

Filter

top acrylic

pressure plate

Pellicon10_2_06_1.eps

Gasket Plate

Exploded View of Acrylic Pellicon

® 

  

Cassette Filter Holder.

manifold adapter 

plate

®

Manual Process-Scale Holder Installation

1.  Loosen the nuts on the tie rods of the holder and remove the nuts, washers and 

end plate.

2.  Inspect the tie rods and nuts for signs of burrs or stripped threads. Replace any 

damaged components. Nuts must turn freely on the tie rods to ensure proper 

tightening of the holder.

3.  Clean the manifold adapter plate (XXPEL3MAP) with an alcohol wipe.
4.  Slide the manifold adapter plate onto the holder against the holder’s manifold plate, 

with the solid light grey side labeled “Manifold Side” towards the manifold, and the 

wings resting on the tie rods.  Slide the manifold adapter plate directly up against the 

stainless steel manifold.

Summary of Contents for Pellicon 3 Cassettes

Page 1: ...ale Holder Installation 4 Hydraulic Process Scale Holder Installation 5 Maintenance 7 Flushing and Cleaning 7 Flushing 8 Cleaning 8 Sanitization 9 Depyrogenation 10 Integrity Testing 10 Measurement of...

Page 2: ...TE Pellicon 3 88 cm2 and 0 11 m2 Cassettes must be installed in a Pellicon Cassette Holder Catalog Number XX42PMINI Holder Installation 1 Loosen the nuts on the tie rods of the holder and remove the n...

Page 3: ...wipe 4 Slide the manifold adapter plate onto the holder against the holder s manifold plate with the solid light grey side labeled Manifold Side towards the manifold and the wings resting on the tie...

Page 4: ...ary Tri Clover connection Pellicon Cassette hex nut washer stainless steel bushing handle PERMEATE RETENTATE FEED Pellicon10_2_06_2 eps Gasket Plate manifold adapter plate nut PERMEATE R E T E N T A T...

Page 5: ...wrench and 15 16 in deep hex socket turn each nut 1 8 turn in the sequence shown in Figure 4 When the wrench clicks this indicates that the set force has been reached DO NOT OVER TORQUE Evenness of to...

Page 6: ...d tight 4 Turn on the air supply to the Hydraulic Power Unit A minimum of 80 psig air pressure should be available Check the air pressure on the pressure gauge PI 1 on Hydraulic Power Unit front panel...

Page 7: ...ut replacement of nuts and washers should be considered after every ten installations to maintain high sealing force in the holder 7 When new nuts do not spin freely refurbish the threaded rods with a...

Page 8: ...se the tank drain valve V1 and the tank valve V2 2 Fill the tank with the flushing solution 3 Fully open the retentate valve V4 and permeate valve V5 if present and direct both the retentate and filtr...

Page 9: ...iofilms Biopolymer Proteins and Polyphenolic Membrane Cleaning Agent Concentration Temperature C pH Time min Ultracel NaOH 0 1 N 0 5 N 25 50 13 13 7 30 60 Biomax NaOH 0 1 N 0 5 N 25 50 13 13 7 30 60 N...

Page 10: ...c Acid 0 1M 30 50 1 30 NaOH 0 1N 25 50 13 30 Ultracel NaOH 0 1N 25 50 13 30 Use milder conditions if effectiveness of agent is still observed Better membrane life is expected with lower concentration...

Page 11: ...l the tank with filtered deionized water water for injection or reverse osmosis permeate The flush water must be extremely pure to avoid fouling the membranes or introducing other contaminants into th...

Page 12: ...0 40 0 734 75 2 24 1 023 46 4 8 1 551 102 2 39 0 748 73 4 23 1 047 44 6 7 1 598 100 4 38 0 762 71 6 22 1 072 42 8 6 1 648 98 6 37 0 777 69 8 21 1 098 41 0 5 1 699 Based on Water Fluidity Relative to...

Page 13: ...ess compression and ensures that the units will not leak externally NOTE The storage agent used must comply with applicable local regulations Recommended Storage Solutions for Pellicon 3 Cassette Filt...

Page 14: ...completely flushed Flush system and cassette System and cassette not completely cleaned Clean system and cassette Symptom Possible Cause Remedy High NWP Damage to membrane or cassette Integrity test...

Page 15: ...xed below fluid air interface Vortex in feed container Add baffle to break vortex or reduce mixing speed Retentate splashing Fix retentate line below fluid in feed air interface container Pump cavitat...

Page 16: ...atory matters to the best of our knowledge and ability but without obligation or liability Existing laws and regulations are to be observed in all cases by our customers This also applies in respect t...

Reviews: