Pellicon
®
3 Cassettes Installation and User Guide
2
Introduction
This guide provides installation and
maintenance procedures for Pellicon
®
3
cassettes. It is not intended to provide
validation protocols or supporting data
for validation purposes. Please refer
to the cassette Validation Guide for
this information. Please refer to the
Certificate of Quality supplied with each
cassette for specifications.
Membrane Type
Install filters containing only one type
of membrane in the filter holder at one
time. Do not mix filters with different
pore sizes or nominal molecular weight
cutoffs. The area of membrane used
depends on the filter surface area
required for your particular application.
Pump Capacity
When operating Pellicon
®
3 cassettes,
select a pump with adequate capacity.
Recommended feed crossflow rate for
cassettes is 4 - 6 liter/min/m
2
. Optimal
cross flow will depend on the actual
solution being filtered.
Water Quality
Reverse osmosis (RO) water or water for
injection (WFI) is recommended
Installation
Pellicon
®
3 88 cm
2
and 0.11 m
2
Cassette Holder Installation
NOTE
Pellicon
®
3 88 cm
2
and 0.11 m
2
Cassettes must be installed in a Pellicon
®
Cassette Holder, Catalog Number XX42PMINI.
Holder Installation
1. Loosen the nuts on the tie rods of the
holder and remove the nuts, washers,
tie rod spacers and end plate.
2. Inspect the tie rods and nuts for signs
of burrs or stripped threads. Replace
any damaged components. Nuts must
turn freely on the tie rods to ensure
proper tightening of the holder.
3. Slide the Pellicon
®
3 Cassette onto
holder so that the tie rods pass
through the cutouts in the Pellicon
®
3 Cassette. Repeat to install one or
two additional Pellicon
®
3 Cassettes
if required.
4. Slide the end plate onto the tie rods
and press the end plate against the
cassette.
5. Install the tie rod spacers, washers and nuts. Hand-tighten the nuts, alternating from one
nut to the other nut.
NOTE
Uneven tightening of the nuts can damage the Pellicon
®
Cassette. Nonparallel
plates or compression of the filters at one end can cause leakage.
6. Tighten the nuts using the torque wrench and 9/16 in. socket supplied with the
Pellicon
®
Cassette Holder. If your wrench has a ratchet head, move the lever to the
right lock position to tighten the nuts or to the left lock position to loosen the nuts.
Pellicon
®
3 Cassette
Pellicon
®
Cassette Holder, XX42PMINI
