
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PLC with inteGrateD eLSD ConfiGuration
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PLC 2050/2250/2500 PurifiCation SyStemS
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Clean the Nebulizer
with time, the nebulizer can get clogged by sample and mobile phase materials. a dirty or
clogged nebulizer can cause increased baseline noise and decreased sensitivity. the following
procedure can be used to clean the nebulizer.
the nebulizer is a consumable component. nebulizer lifespan depends directly on
the conditions of use and care. this section provides general directions for nebulizer
maintenance, but if cleaning procedures are ineffective, consider a nebulizer replacement.
NOTICE
Handle the nebulizer carefully, and do not disassemble the rear component protected by a
white, heat-shrinking tubing. Improper handling of the nebulizer will permanently damage it.
The nebulizer rear part results from a very tricky setting which must not be disassembled
for any reason. If it has been removed or unscrewed, the only solution is to proceed to a
nebulizer replacement.
Remove the Nebulizer
1. Switch off the PLC Purification System.
2. Disconnect the PLC Purification System from the mains.
3. Stop the flow of gas to the PLC Purification System.
4. remove the chamber shield.
5. Disconnect the nebulizer liquid inlet from the splitter tubing.
6. Disconnect the gas inlet tubing from the nebulizer.
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to remove the tube, apply manual pressure to the white push sleeve to disengage the
grab ring, and then withdraw the tube from the fitting.
7. hold the nebulizer with one hand, and then unscrew the black plastic nut to remove the
nebulizer from the glass chamber with the other hand. Do not pull or twist the nebulizer
capillary.
8. remove the gas inlet fitting and the black plastic nut to avoid damaging the seals with the
cleaning solvent.
Clean the Nebulizer
1. fill an ultrasonic bath with water. fill a beaker (50 or 100 mL) with approximately 2 cm of
appropriate solvent. the solvent is dependent on the nature of the material that is present
in the nebulizer. in most cases, ethanol is a satisfactory solvent.
2. Place the nebulizer vertically in the beaker. the nebulizer outlet should be placed at the
bottom of the bath and the nebulizer inlet liquid tubing should be pointing up. take care
to ensure that the rear component of the nebulizer is not in contact with the solvent.
3. Clean the nebulizer for approximately 30 minutes.
4. replace the solvent with water and clean for an additional 30 minutes.