
5.1.5
Final checks
Checklist
Make sure that the actions listed below are completed before the system is started.
•
Check the condition of all connections and gaskets.
•
Check that no chemicals that may be harmful to the system will be used.
•
Check that the pump is filled with the correct lubricant oil. Refer to the pump supplier
information included in the ÄKTAprocess documentation package for details.
•
Check that all inlets and outlets to the system are connected, closed or in the state
that they are supposed to be before the system is started.
-
Inlets that are not in use must be closed.
-
Outlets that are not in use must be capped with blind caps or fitted with tubing
directed to waste.
•
For systems that have a sample pump, check that all protection caps are mounted
on the sample pump cable connectors and that a blind plug is mounted on the
pneumatic connector if the system is run with the sample pump disconnected.
•
If the sample pump is disconnected, the alarm for the sample inlet valves must be
disabled. To avoid having to repeat this instruction, the alarm should be disabled in
the System Settings in UNICORN: System:Settings:Alarms:InletSam-
ple_Valves_Alarm:Disable. Do not forget to enable the alarm when the sample
pump is connected again.
•
Check that the column connection complies with the requirements in the column
instruction manual.
•
Check that the air sensor alarm function is enabled when a column is connected. If
air is detected an alarm will sound and the system will pause the current operation,
thereby protecting the column from air.
•
Perform an alarm test according to Alarm test, on page 80.
High pressure safety monitoring
The ALP-900 safety module that monitors the pump/system pressure is a protection
for the system and not the column.
If the pressure limit of the column is lower than that of the system the high pressure
alarm settings in UNICORN must be changed accordingly.
Column protection from overpressure can be accomplished, for example, by adding a
relief valve or burst disc before the column.
ÄKTAprocess Operating Instructions 29-0252-49 AA
123
5 Operation
5.1 Prepare the system
5.1.5 Final checks
Summary of Contents for AKTAprocess
Page 1: ...GE Healthcare Life Sciences ÄKTAprocess Operating Instructions Original instructions ...
Page 2: ......
Page 179: ......