FTS LYOSTAR 3, Operator'S Manual

Page: 57 / 82

Rev 006, 01/14 47
© SP Scientific 2014
Chapter
9
Praxair’s ControLyo™ Nucleation
On-Demand Technology
THE FOLLOWING SECTION IS INTENDED FOR LYOSTAR™ 3 LYOPHILIZERS CONFIGURED
WITH PRAXAIR'S CONTROLYO™ NUCLEATION ON-DEMAND TECHNOLOGY. FOR
ADDITIONAL INFORMATION, REFER TO YOUR CONTROL SYSTEM OPERATOR’S MANUAL.
ControLyo™ Nucleation On-Demand Technology is a new technology developed by
Praxair, Inc., which utilizes a series of pressurization and depressurization events
within the product-drying chamber using a gas to enable controllable instantaneous
and homogeneous nucleation of the freezing event for all product containers in the
chamber.
Note: For information on Praxair's ControLyo™ Nucleation On-Demand Technology, read the
following section and refer to your control system operator’s manual.
WARNING! WITHOUT PROPER VENTILATION, OPERATION OF CONTROLYO™ MAY CAUSE
THE OXYGEN CONCENTRATION OF AMBIENT AIR TO DROP BELOW ACCEPTABLE LEVELS.
TO ENSURE THAT VENTILATION IS ADEQUATE FOR THE DEPRESSURIZATION PROCESS,
THE VOLUME TO VENT PERCENTAGE RATIO (V
V
/V
R
) MUST BE LESS THAN 6.5%, WHERE V
V
EQUALS THE PRODUCT CHAMBER VOLUME MULTIPLIED BY 10, AND V
R
EQUALS THE
TOTAL VOLUME OF THE ROOM IN WHICH THE LYOPHILIZER IS LOCATED. IN ADDITION,
SP SCIENTIFIC RECOMMENDS THE USE OF AN O
2
SENSOR TO MONITOR OXYGEN
CONCENTRATION WHILE OPERATING CONTROLYO™.
Note: The volume of a standard LyoStar™ 3 chamber is 3.99 ft
3
/ .113 m
3
.
NOISE FROM THE EQUIPMENT UNDER NORMAL OPERATING CONDITIONS SHALL NOT
EXCEED 85 DBA WHEN MEASURED AT ANY POINT THREE (3) FEET AWAY FROM THE
EQUIPMENT. LYOPHILIZERS EQUIPPED WITH CONTROLYO™ SHALL EXCEED THE
SPECIFIED NOISE LEVEL RATING FOR APPROXIMATELY 3 TO 5 SECONDS DURING
DEPRESSURIZATION. SP SCIENTIFIC RECOMMENDS THE USE OF BOTH HEARING AND
EYE PROTECTION DURING THE CONTROLYO™ PROCESS.