MIRI
®
TL family`s multiroom IVF incubators User Manual Rev. 1.0
23
VOCs are typically measured in parts per million (ppm.) They can also be reported in
parts per billion (ppb.) For IVF, the recommended count below 0.5 ppm; the total quantity
of VOCs should be below <0.2 ppm or preferably zero.
High levels of VOCs (over 1 ppm) are toxic to embryos, resulting in poor embryo devel-
opment and even probable failure to reach the blastocyst stage.
VOC levels in the 0.5 ppm range will typically allow an acceptable blastocyst development
and reasonable pregnancy rates but will likely result in a high percentage of miscarriages.
A combined HEPA and VOC filter (carbon filter) are integrated into the construction of
the MIRI
®
TL6 and MIRI
®
TL12 multiroom IVF incubator. Before entering the multiroom
IVF incubator, the gas is sent through the filter in a single pass. Then, upon return from
the compartment, the gas is filtered again. The recirculation system constantly filters gas
in the multiroom IVF incubator.
The combined HEPA and VOC filter are mounted on the device's back to ease access and
replacement.
12.1 Installation of a new filter capsule
Two blue caps that are installed on the filter can be discarded during unwrapping. Correct
filter performance is crucial for the system's performance.
The filter element must be changed every 3 months. Mark the date when it is
put on, and make sure to keep this interval!
Start by putting the blue fittings on the filter into the filter holder sockets. The flow arrow
on the MIRI
®
TL6 and MIRI
®
TL12 multiroom IVF incubator and the filter should point in
the same direction.
Figure 12.1
The flow arrow on the multiroom IVF incubator
Figure 12.2
The direction of pulling the filter