Detector calibration
PlasmaQuant MS product family
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9
Detector calibration
The PlasmaQuant MS features a unique all-digital extended dynamic range detector. If
the option of auto attenuation is selected, the ASpect MS software automatically
chooses a suitable attenuation mode for the detector. The auto attenuation offers a
wide calibration range with the lowest possible detection limit. When the detector
signal is low, the software automatically turns the attenuation off. This gives the
highest possible sensitivities for the analytes at a low concentration level, achieving
the lowest possible detection limit.
Setup of attenuation factors covers these topics:
Attenuation Modes
Instrument Initialization and Solution Preparations
Detector Calibration Worksheet
Scan Settings for Attenuation Calibration
Detector Calibration
Attenuation Factors on the existing Worksheet
Attenuation Factors Calibration Troubleshooting
9.1
Attenuation modes
Fig. 47 Schematic of detector attenuation
Attenuation of the detector in the PlasmaQuant MS makes use of a control section and
a gain control as illustrated above. The gain control sets the voltage on the dynode
that is known as the control section of the detector. By modifying the response of the
control section dynode, the number of electrons generated by it when it is struck by
incoming electrons can be modified. There are three different voltage settings that can
be applied to the control section:
No attenuation
Medium attenuation
High attenuation