Covidien INVOS 5100C, Operator'S Manual

Page: 168 / 178

Clinical Studies
B-4 Operator's Manual
Figure B-2. Trend Data, 22 Subjects, 90 Points
B.4
Interventional Studies
In controlled studies of carotid endarterectomy (references 1-3), changes in the rSO2 of 12-20
points (absolute) or 20% to 30% (relative) correlated with changes in the patient’s neurological
status. In these studies, as well as in other interventional studies of general and cardiac surgery
patients (references 4-10), rSO
2
values less than 50 were associated with higher probabilities of a
poor outcome.
1.
Cho H, Nemoto EM, Yonas H, Balzer J: Cerebral monitoring by oximetry And Somatosensory Evoked
Potentials (SSEP) during Carotid Endarterectomy. J Neurosurg, 89:533-38, 1998.
2.
Roberts KW, Crnkowic AP, Linneman LJ: Near infrared spectroscopy detects critical cerebral hypoxia
during carotid endarterectomy in awake patients. Anesthesiology 1998;89(3A):A934.
3.
Samra S, Dy E, Welch K, Dorje P, Zelenock G, Stanley J: Evaluation of a cerebral oximeter as a monitor of
cerebral ischemia during carotid endarterectomy. Anesthesiology 2000;93:964-70.
4.
Murkin JM, Adams SJ, Novick RJ, Quantz M, Bainbridge D, Iglesias I, Cleland A, Schaefer B, Irwin B, Fox S.
Monitoring brain oxygen saturation during coronary bypass surgery: a randomized, prospective study.
Anesth Analg. 2007 Jan;104(1):51-8.
5.
Casati A, Fanelli G, Pietropaoli P, Proietti R, Tufano R, Montanini S. Monitoring cerebral oxygen satura-
tion in elderly patients undergoing general abdominal surgery: a prospective cohort study. Eur J
Anaesthesiol. 2006 Jul 7;:1-7 [Epub ahead of print].
6.
Casati A, Fanelli G, Pietropaoli P, Proietti R, Tufano R, Danelli G, Fierro G, De Cosmo G, Servillo G. Contin-
uous monitoring of cerebral oxygen saturation in elderly patients undergoing major abdominal
surgery minimizes brain exposure to potential hypoxia. Anesth Analg. 2005 Sep;101(3):740-7.
22 patients, 90 points. y=1.0372x–0.0062, R
2
=0.9609, bias=–0.02, standard devi-
ation=1.63.